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Autor:
Mariana Oksdath Mansilla, Camilo Salazar-Hernandez, Sally L. Perrin, Kaitlin G. Scheer, Gökhan Cildir, John Toubia, Kristyna Sedivakova, Melinda N. Tea, Sakthi Lenin, Elise Ponthier, Erica C. F. Yeo, Vinay Tergaonkar, Santosh Poonnoose, Rebecca J. Ormsby, Stuart M. Pitson, Michael P. Brown, Lisa M. Ebert, Guillermo A. Gomez
Publikováno v:
BMC Biomedical Engineering, Vol 3, Iss 1, Pp 1-14 (2021)
Abstract Background Organoids are a reliable model used in the study of human brain development and under pathological conditions. However, current methods for brain organoid culture generate tissues that range from 0.5 to 2 mm of size, which need to
Externí odkaz:
https://doaj.org/article/bb2b7d7fa4cd4072a534f3d2e82c57e7
Autor:
Lisa M Ebert, Wenbo Yu, Tessa Gargett, John Toubia, Paris M Kollis, Melinda N Tea, Brenton W Ebert, Cedric Bardy, Mark van den Hurk, Claudine S Bonder, Jim Manavis, Kathleen S Ensbey, Mariana Oksdath Mansilla, Kaitlin G Scheer, Sally L Perrin, Rebecca J Ormsby, Santosh Poonnoose, Barbara Koszyca, Stuart M Pitson, Bryan W Day, Guillermo A Gomez, Michael P Brown
Publikováno v:
Clinical & Translational Immunology, Vol 9, Iss 10, Pp n/a-n/a (2020)
Abstract Objectives Targeted immunotherapies such as chimeric antigen receptor (CAR)‐T cells are emerging as attractive treatment options for glioblastoma, but rely on identification of a suitable tumor antigen. We validated a new target antigen fo
Externí odkaz:
https://doaj.org/article/d95e2e808e74470a9794a5b6b9f9e770
Publikováno v:
Physical Review A. 107
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bdb35ec1cfd3e4df2d36c6adc53c39a0
https://doi.org/10.1103/physreva.107.053704
https://doi.org/10.1103/physreva.107.053704
Autor:
Sakthi Lenin, Elise Ponthier, Kaitlin G. Scheer, Erica C. F. Yeo, Melinda N. Tea, Lisa M. Ebert, Mariana Oksdath Mansilla, Santosh Poonnoose, Ulrich Baumgartner, Bryan W. Day, Rebecca J. Ormsby, Stuart M. Pitson, Guillermo A. Gomez
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 9, p 4322 (2021)
Glioblastoma is one of the most common and lethal types of primary brain tumor. Despite aggressive treatment with chemotherapy and radiotherapy, tumor recurrence within 6–9 months is common. To overcome this, more effective therapies targeting canc
Externí odkaz:
https://doaj.org/article/55bd8747d563491eb5b4e5dad723bbb9
Autor:
Mahdi Yaghoobi, Michael S. Samuel, Rebecca J. Ormsby, Damon J. Tumes, Guillermo A. Gomez, Kaitlin G. Scheer, Narjes Sadat Bagherian, Santosh Poonnoose, Eric Fornaciari, Mark D. McDonnell, Amin Zadeh Shirazi
Publikováno v:
British Journal of Cancer
BackgroundGlioblastoma is the most aggressive type of brain cancer with high-levels of intra- and inter-tumour heterogeneity that contribute to its rapid growth and invasion within the brain. However, a spatial characterisation of gene signatures and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::70e5a7f52a8856ff71a038d688355bdf
https://doi.org/10.1038/s41416-021-01394-x
https://doi.org/10.1038/s41416-021-01394-x
The Bistritzer-MacDonald continuum model (BM model) describes the low-energy moir\'e bands for twisted bilayer graphene (TBG) at small twist angles. We derive a generalized continuum model for TBG near any commensurate twist angle, which is character
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::efa6d22126450b1010b1917472fcc336
http://arxiv.org/abs/2203.06163
http://arxiv.org/abs/2203.06163
Autor:
Lisa M. Ebert, Sakthi Lenin, Santosh Poonnoose, Ulrich Baumgartner, Stuart M. Pitson, Melinda N Tea, Erica C. F. Yeo, Kaitlin G. Scheer, Guillermo A. Gomez, Elise Ponthier, Rebecca J. Ormsby, Bryan W. Day, Mariana Oksdath Mansilla
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 4322, p 4322 (2021)
International Journal of Molecular Sciences
Volume 22
Issue 9
International Journal of Molecular Sciences
Volume 22
Issue 9
Glioblastoma is one of the most common and lethal types of primary brain tumor. Despite aggressive treatment with chemotherapy and radiotherapy, tumor recurrence within 6–9 months is common. To overcome this, more effective therapies targeting canc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::613844e9dc89e7c30d3e59c749d972a5
https://www.mdpi.com/1422-0067/22/9/4322
https://www.mdpi.com/1422-0067/22/9/4322
Autor:
Gökhan Cildir, Mariana Oksdath Mansilla, Melinda N. Tea, Elise Ponthier, Sally L. Perrin, Guillermo A. Gomez, Sakthi Lenin, Michael P. Brown, John Toubia, Rebecca J. Ormsby, Stuart M. Pitson, Camilo Salazar-Hernandez, Kaitlin G. Scheer, Kristyna Sedivakova, Lisa M. Ebert, Santosh Poonnoose, Vinay Tergaonkar, Erica C. F. Yeo
Publikováno v:
BMC Biomedical Engineering, Vol 3, Iss 1, Pp 1-14 (2021)
BMC Biomedical Engineering
BMC Biomedical Engineering
BackgroundOrganoids are a reliable model used in the study of human brain development and under pathological conditions. However, current methods for brain organoid culture generate tissues that range from 0.5 to 2 mm of size, which need to be consta
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::db9b05b0e2629c336f9d1f33fc87bc3e
https://doi.org/10.1186/s42490-021-00049-5
https://doi.org/10.1186/s42490-021-00049-5
Autor:
Narjes Sadat Bagherian, Mahdi Yaghoobi, Amin Zadeh Shirazi, Michael S. Samuel, Rebecca J. Ormsby, Damon J. Tumes, Guillermo A. Gomez, Mark D. McDonnell, Santosh Poonnoose, Eric Fornaciari, Kaitlin G. Scheer
Publikováno v:
Clinical Cancer Research. 27:PO-004
Glioblastoma is the most aggressive type of brain cancer with high-levels of intra- and inter-tumour heterogeneity that contribute to its rapid growth and invasion within the brain. Here, we have used a deep convolutional neural network (DCNN) as a s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e140870d383eeb16f05254b4ea660301
https://doi.org/10.1158/1557-3265.adi21-po-004
https://doi.org/10.1158/1557-3265.adi21-po-004