Zobrazeno 1 - 10
of 124
pro vyhledávání: '"G. STANLEY MCKNIGHT"'
Autor:
Jordan L Pauli, Jane Y Chen, Marcus L Basiri, Sekun Park, Matthew E Carter, Elisenda Sanz, G Stanley McKnight, Garret D Stuber, Richard D Palmiter
Publikováno v:
eLife, Vol 11 (2022)
The parabrachial nucleus (PBN) is a major hub that receives sensory information from both internal and external environments. Specific populations of PBN neurons are involved in behaviors including food and water intake, nociceptive responses, breath
Externí odkaz:
https://doaj.org/article/ee8ce862de90472d976a0c522ff83497
Autor:
Xiaofang Wang, Li Jiang, Ka Thao, Caroline R. Sussman, Timothy LaBranche, Michael Palmer, Peter C. Harris, G. Stanley McKnight, Klaus P. Hoeflich, Stefanie Schalm, Vicente E. Torres
Publikováno v:
J Am Soc Nephrol
BACKGROUND: Upregulation of cAMP-dependent and cAMP-independent PKA signaling is thought to promote cystogenesis in polycystic kidney disease (PKD). PKA-I regulatory subunit RIα is increased in kidneys of orthologous mouse models. Kidney-specific kn
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4d80c427f549873fee3233309ffbae68
https://doi.org/10.1681/asn.2021081125
https://doi.org/10.1681/asn.2021081125
Autor:
Marcus L Basiri, Jane Y Chen, Jordan L Pauli, Sekun Park, Matthew E Carter, Elisenda Sanz, G Stanley McKnight, Garret D Stuber, Richard D Palmiter
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f72339f214aee0f92a159d8f01574d06
https://doi.org/10.7554/elife.81868.sa2
https://doi.org/10.7554/elife.81868.sa2
Autor:
Brian W Jones, Jennifer Deem, Thomas J Younts, Michael Weisenhaus, Christina A Sanford, Margaret C Slack, Jenesa Chin, Daniela Nachmanson, Alex McKennon, Pablo E Castillo, G Stanley McKnight
Publikováno v:
eLife, Vol 5 (2016)
Protein Kinase A (PKA) mediates synaptic plasticity and is widely implicated in learning and memory. The hippocampal dentate gyrus (DG) is thought to be responsible for processing and encoding distinct contextual associations in response to highly si
Externí odkaz:
https://doaj.org/article/ccb6d67e37424b3596d95ff7b4e0d75b
Autor:
Elisenda Sanz, Ryan Evanoff, Albert Quintana, Elizabeth Evans, Jeremy A Miller, Chemyong Ko, Paul S Amieux, Michael D Griswold, G Stanley McKnight
Publikováno v:
PLoS ONE, Vol 8, Iss 6, p e66179 (2013)
Male spermatogenesis is a complex biological process that is regulated by hormonal signals from the hypothalamus (GnRH), the pituitary gonadotropins (LH and FSH) and the testis (androgens, inhibin). The two key somatic cell types of the testis, Leydi
Externí odkaz:
https://doaj.org/article/c2087f484e47478eaf2325c594e5f822
Kisspeptin-expressing neurons in the rostral periventricular region of the third ventricle (RP3V) play an essential role in female reproduction. However, adult male mice were reported to have very few Kisspeptin-expressing neurons in the RP3V compare
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::acd7942dbbc66db44bfd20c824a7419f
https://doi.org/10.1101/2020.12.03.410878
https://doi.org/10.1101/2020.12.03.410878
Publikováno v:
PLoS ONE, Vol 6, Iss 4, p e18772 (2011)
We employed the Cre recombinase/loxP system to create a mouse line in which PKA activity can be inhibited in any cell-type that expresses Cre recombinase. The mouse line carries a mutant Prkar1a allele encoding a glycine to aspartate substitution at
Externí odkaz:
https://doaj.org/article/8f9cb610f0424c65be1986e4c1722076
Autor:
Michael Weisenhaus, Margaret L Allen, Linghai Yang, Yuan Lu, C Blake Nichols, Thomas Su, Johannes W Hell, G Stanley McKnight
Publikováno v:
PLoS ONE, Vol 5, Iss 4, p e10325 (2010)
AKAP5 (also referred to as AKAP150 in rodents and AKAP79 in humans) is a scaffolding protein that is highly expressed in neurons and targets a variety of signaling molecules to dendritic membranes. AKAP5 interacts with PKA holoenzymes containing RIIa
Externí odkaz:
https://doaj.org/article/f5f83e536db14ac4a3ae330247768049
Autor:
Catherine W Morgans, Patricia Kensel-Hammes, James B Hurley, Kimberly Burton, Rejean Idzerda, G Stanley McKnight, Sandra M Bajjalieh
Publikováno v:
PLoS ONE, Vol 4, Iss 4, p e5230 (2009)
The Synaptic Vesicle Protein 2 (SV2) family of transporter-like proteins is expressed exclusively in vesicles that undergo calcium-regulated exocytosis. Of the three isoforms expressed in mammals, SV2B is the most divergent. Here we report studies of
Externí odkaz:
https://doaj.org/article/4b28ed2fa81c40f085348edb49409863
Autor:
Haifeng Yin, Jing Li, L. Fernando Santana, Yi Chen, Stephen W. Luckey, Merle L. Gilbert, Xiaoyun Guo, Lei Li, G. Stanley McKnight, John D. Scott, Qinghang Liu, Benjamin M.L. Drum
Publikováno v:
Cardiovascular research, vol 113, iss 2
Li, L; Li, J; Drum, BM; Chen, Y; Yin, H; Guo, X; et al.(2017). Loss of AKAP150 promotes pathological remodelling and heart failure propensity by disrupting calcium cycling and contractile reserve. Cardiovascular Research, 113(2), 147-159. doi: 10.1093/cvr/cvw221. UC Davis: Retrieved from: http://www.escholarship.org/uc/item/0912z16q
Li, L; Li, J; Drum, BM; Chen, Y; Yin, H; Guo, X; et al.(2017). Loss of AKAP150 promotes pathological remodelling and heart failure propensity by disrupting calcium cycling and contractile reserve. Cardiovascular Research, 113(2), 147-159. doi: 10.1093/cvr/cvw221. UC Davis: Retrieved from: http://www.escholarship.org/uc/item/0912z16q
© 2016 The Author. Aims Impaired Ca2+cycling and myocyte contractility are a hallmark of heart failure triggered by pathological stress such as hemodynamic overload. The A-Kinase anchoring protein AKAP150 has been shown to coordinate key aspects of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ed411433a7cd22b2f8adb9f95e09c1c8
https://doi.org/10.1093/cvr/cvw221
https://doi.org/10.1093/cvr/cvw221