Zobrazeno 1 - 10
of 10
pro vyhledávání: '"G. S. Shepelkova"'
Autor:
G. S. Shepelkova, A. S. Zaytseva, V. V. Evstifeev, E. N. Adamovskaya, E. I. Shmelev, V. V. Yeremeev
Publikováno v:
Медицинская иммунология, Vol 26, Iss 3, Pp 607-612 (2024)
Hypersensitivity pneumonitis (HP) is a complex interstitial pulmonary syndrome. This clinical entity is characterized by sensitization to a specific antigen. Early detection of this antigen is associated with an increased likelihood of a favorable ou
Externí odkaz:
https://doaj.org/article/5d4deaf677f6486788ab36976925350a
Publikováno v:
Инфекция и иммунитет, Vol 11, Iss 3, Pp 473-480 (2021)
The protection against tuberculosis infection is largely determined by the ability of host tissue macrophages to limit the growth and spread of mycobacteria. Able to multiply within the host macrophages, mycobacteria have developed a number of protec
Externí odkaz:
https://doaj.org/article/7c837d3104524d8388a10a3e8c4837e4
Publikováno v:
Медицинская иммунология, Vol 21, Iss 6, Pp 1015-1022 (2020)
Decades of research on the mechanisms of immunological protection against Mycobacterium tuberculosis, the causative agent of tuberculosis (ТВ), did not allow us to draw a final conclusion about the relative importance of specific pathways when form
Externí odkaz:
https://doaj.org/article/4a39108113b1424ab76fc8ed87b4d9c9
Publikováno v:
Медицинская иммунология, Vol 21, Iss 3, Pp 555-558 (2019)
Since 1924, BCG vaccine is used to protect children from the most severe forms of tuberculosis. At the same time, the protective effect of BCG in adults is variable. The potential for revaccination with live vaccine is further limited by the rapid sp
Externí odkaz:
https://doaj.org/article/106f0cdfdf5d42be9b453ae931a7cb92
Publikováno v:
Инфекция и иммунитет, Vol 8, Iss 3, Pp 309-315 (2018)
In 2015, more than 10% of tuberculosis (TB)-related deaths were attributable to M. tuberculosis with multiple drug-resistance (MDR-TB) and extensively drug-resistance (XDR-TB) (WHO 2016). In combination with insufficient commitment to the treatment r
Externí odkaz:
https://doaj.org/article/8f1cabfc42b147ab88f4c0f282339361
DURATION OF IMMUNE RESPONSE INDUCED BY THE VACCINE BASED ON RECOMBINANT Ag85, TB10 AND FliC PROTEINS
Autor:
V. V. Yeremeev, I. V. Dukhovlinov, A. I. Orlov, G. S. Shepelkova, E. A. Fedorova, M. B. Balazovsky, V. Ya. Gergert
Publikováno v:
Медицинская иммунология, Vol 20, Iss 2, Pp 271-276 (2018)
Already about one hundred years BCG remains the only widely used tuberculosis (TB) vaccine. It is known that intensity of the BCG-induced Th1 immune response decreases over time and comes to naught within 10-15 years. It significantly distinguishes B
Externí odkaz:
https://doaj.org/article/43957476b69644db91835395497686c3
Publikováno v:
Медицинская иммунология, Vol 0, Iss 0 (2019)
Since 1924, BCG vaccine is used to protect children from the most severe forms of tuberculosis. At the same time, the protective effect of BCG in adults is variable. The potential for revaccination with live vaccine is further limited by the rapid sp
Externí odkaz:
https://doaj.org/article/38d15a5f9bf140ee86ca03254183a285
DURATION OF IMMUNE RESPONSE INDUCED BY THE VACCINE BASED ON RECOMBINANT Ag85, TB10 AND FliC PROTEINS
Autor:
Vladimir Yeremeev, V. Ya. Gergert, M. B. Balazovsky, A. I. Orlov, I. V. Dukhovlinov, E. A. Fedorova, G. S. Shepelkova
Publikováno v:
Medicinskaâ Immunologiâ, Vol 20, Iss 2, Pp 271-276 (2018)
Already about one hundred years BCG remains the only widely used tuberculosis (TB) vaccine. It is known that intensity of the BCG-induced Th1 immune response decreases over time and comes to naught within 10-15 years. It significantly distinguishes B
Autor:
Konstantin B. Shumaev, Yu N Belenkov, A. K. Tikhaze, Valery I. Kapelko, Galina G. Konovalova, Vadim Z. Lankin, G. S. Shepelkova, O M Panasenko
Publikováno v:
Biochemistry (Moscow). 72:1081-1090
Low-molecular-weight aldehydes (glyoxal, methylglyoxal, 3-deoxyglucosone) generated on autooxidation of glucose under conditions of carbonyl stress react much more actively with amino groups of L-lysine and epsilon-amino groups of lysine residues of
Autor:
Konstantin B. Shumaev, Elena Kumskova, G. S. Shepelkova, S. A. Gubkina, Enno K. Ruuge, Vadim Z. Lankin
Publikováno v:
Biochemistry. Biokhimiia. 74(4)
The EPR signal recorded in reaction medium containing L-lysine and methylglyoxal is supposed to come from the anion radical (semidione) of methylglyoxal and cation radical of methylglyoxal dialkylimine. These free radical inter-mediates might be form