Výsledky vyhledávání - "G. S. R. Subba Rao"

Synthetic Triterpenoid Cyano Enone of Methyl Boswellate Activates Intrinsic, Extrinsic, and Endoplasmic Reticulum Stress Cell Death Pathways in Tumor Cell Lines

Autor: John C. Reed, Sanjay Singh, Michael Cuddy, Palaniyandi Ravanan, Shu-ichi Matsuzawa, Priti Talwar, Satoshi Ogasawara, Renata Sano, Paturu Kondaiah, G. S. R. Subba Rao

Publikováno v: Molecular Cancer Therapeutics. 10:1635-1643

We explored the effect of a novel synthetic triterpenoid compound cyano enone of methyl boswellates (CEMB) on various prostate cancer and glioma cancer cell lines. CEMB displayed concentration-dependent cytotoxic activity with submicromolar lethal do

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::977fe6bb5963d2c0ef53a1239b341017
https://doi.org/10.1158/1535-7163.mct-10-0887

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Synthetic studies towards the nor-triterpene pfaffic acid: Synthesis of DEF ring fragment via tandem radical cyclization rearrangement reactions

Autor: Krishna P. Kaliappan, G. S. R. Subba Rao, Purakkattle J. Biju

Publikováno v: ARKIVOC, Vol 2004, Iss 8, Pp 37-45 (2004)

A tandem 5-exo-trig-vinyl-3-exo-radical cyclization-rearrangement reaction and its allylic radical version was developed (8 & 15 to 9 & 16 respectively) for the synthesis of DEF ring system of the nor-tritepene Pfaffic acid 1.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f40bd241fb2630f8ba46e9a1a0453e83
https://doi.org/10.3998/ark.5550190.0005.806

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Synthesis based on cyclohexadienes Part 36: an efficient methodology for the construction of spiro[4.5]decanes: a formal synthesis of acorone

Autor: K. Pramod, P. John Biju, G. S. R. Subba Rao

Publikováno v: ARKIVOC, Vol 2003, Iss 3, Pp 88-103 (2003)

An efficient strategy for the contruction of spiro[4.5] decanes is described and involves a bridgehead substitution of a methoxyl group by a methyl group followed by an oxidative cleavage of the tricyclo[5.2.2.0(1,5)] undecane 25 to produce the spiro

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::653619bcf53660520a181d9869190aa2
https://www.arkat-usa.org/arkivoc-journal/browse-arkivoc/ark.5550190.0004.310

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Synthesis based on cyclohexadienes. Part 35: Synthesis of some polyquinane derivatives

Autor: P. John Biju, G. S. R. Subba Rao, M. S. Laxmisha

Publikováno v: Journal of the Chemical Society, Perkin Transactions 1. :4512-4519

A new strategy for the synthesis of a [4.3.3]propellane derivative and an angular triquinane is described starting from the tetracyclic compounds 8 and 15. The synthesis of the [4.3.3]propellane involved a radical cyclisation and a Beckmann fragmenta

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::814b66b729ddb3f5061bcc0ddf54d749
https://doi.org/10.1039/b003548n

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Synthesis based on cyclohexadienes. Part 34. A tandem cationic rearrangement–ene cyclisation route to 2-pupukeanone

Autor: M. S. Laxmisha, G. S. R. Subba Rao, P. John Biju, Krishna P. Kaliappan

Publikováno v: Journal of the Chemical Society, Perkin Transactions 1. :3714-3718

A new strategy for the construction of the isotwistane skeleton is reported from easily available cyclohexadienes, which involves a one-pot cationic skeletal rearrangement and ene cyclisation of a bicyclo[2.2.2]octenone derivative and a cationic rear

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::bbb2a9daafd011610e10201ad4bfccdf
https://doi.org/10.1039/b003409f

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Aromatics to polyquinanes: A general method for the construction of tricyclo[6.3.0.04,8]-and tricyclo[6.3.0.02,6]undecanes

Autor: G. S. R. Subba Rao, P. John Biju

Publikováno v: Tetrahedron Letters. 40:9379-9382

The conversion of aromatic compounds to linear and angular triquinanes is described and involves a 5-exo-trig-allyl radical cyclization as the key reaction for constructing the strained ketones 9 and 18 , which are then transformed into the quinanes

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::1314c91598b172c12b4f42d47e8754fa
https://doi.org/10.1016/s0040-4039(99)02026-2

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A highly flexible route to tricyclo[4.3.1.03.7]-, and tricyclo[4.3.0.04,10]decanes A short synthesis of pupukean-2-one

Autor: G. S. R. Subba Rao, P. John Biju

Publikováno v: Tetrahedron Letters. 40:181-184

An efficient strategy for the construction of tricyclo[4.3.1.03,7]-, and tricyclo[4.3.0.04,10]decanes is described which involves a novel one-pot tandem acid-catalyzed rearrangement followed by an ene cyclization as key step and is exemplified by the

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::813fa74e02f023804f1207fea9241b96
https://doi.org/10.1016/s0040-4039(98)80053-1

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