Zobrazeno 1 - 10
of 29
pro vyhledávání: '"G. S. Posterino"'
Publikováno v:
Journal of Physiology and Biochemistry. 76:111-121
Intrauterine growth restriction (IUGR) affects vascular reactivity in older rats, but at present the causative factors for this change are unknown. Therefore, we investigated downstream events associated with vascular reactivity, specifically, Ca2+-r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c0f65afa4ff86a3f0ab7c2c61897d614
https://doi.org/10.1007/s13105-020-00724-6
https://doi.org/10.1007/s13105-020-00724-6
Autor:
G. S. Posterino, Janelle P. Mollica, Graham D. Lamb, Cedric R. Lamboley, David W. Greening, Travis L. Dutka, Robyn M. Murphy, VC Weerakkody
Publikováno v:
American Journal of Physiology-Cell Physiology. 312:C316-C327
Nitric oxide is generated in skeletal muscle with activity and decreases Ca2+sensitivity of the contractile apparatus, putatively by S-nitrosylation of an unidentified protein. We investigated the mechanistic basis of this effect and its relationship
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d75f7c1b309c37ff911e8d23bbbe2cf2
https://doi.org/10.1152/ajpcell.00334.2016
https://doi.org/10.1152/ajpcell.00334.2016
Publikováno v:
Physiological Reports. 6:e13954
Intrauterine growth restriction (IUGR) is known to alter vascular smooth muscle reactivity, but it is currently unknown whether these changes are driven by downstream events that lead to force development, specifically, Ca2+ -regulated activation of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::459bbef5d3d49458909fa201fed2dfd1
https://doi.org/10.14814/phy2.13954
https://doi.org/10.14814/phy2.13954
Autor:
Doug A. Brooks, N. Cutri, Janna L. Morrison, Kimberley J. Botting, G. S. Posterino, Leewen Rattanatray, Isabella Caroline McMillen, Kimberley C. W. Wang, Monalisa Padhee, B. Summers-Pearce
Publikováno v:
Clinical and Experimental Pharmacology and Physiology. 39:814-823
Summary 1. World-wide epidemiological and experimental animal studies demonstrate that adversity in fetal life, resulting in intrauterine growth restriction (IUGR), programs the offspring for a greater susceptibility to ischemic heart disease and hea
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::857e9352e7da48920c0422e7a4bd5382
https://doi.org/10.1111/j.1440-1681.2011.05649.x
https://doi.org/10.1111/j.1440-1681.2011.05649.x
Autor:
Janna L. Morrison, Kimberley J. Botting, G. S. Posterino, Stacey Leanne Dunn, Sheridan Gentili, William Yu Chung Wang
Publikováno v:
Journal of Applied Physiology. 111:236-243
The development of the adult cardiac troponin complex in conjunction with changes in cardiac function and cardiomyocyte binucleation has not been systematically characterized during fetal life in a species where maturation of the cardiomyocytes occur
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::393ecbb23ae722f6824f462d4dae8b4b
https://doi.org/10.1152/japplphysiol.00067.2011
https://doi.org/10.1152/japplphysiol.00067.2011
Publikováno v:
The Journal of Physiology. 589:2181-2196
S-Nitrosoglutathione (GSNO) is generated in muscle and may S-glutathionylate and/or S-nitrosylate various proteins involved in excitation–contraction (EC) coupling, such as Na+-K+-ATPases, voltage-sensors (VSs) and Ca2+ release channels (ryanodine
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::126c71dfee615f0fc5906732e39bfb05
https://doi.org/10.1113/jphysiol.2010.200451
https://doi.org/10.1113/jphysiol.2010.200451
Publikováno v:
American Journal of Physiology-Cell Physiology. 296:C1015-C1023
Reactive oxygen species (ROS), such as hydrogen peroxide (H2O2) and nitric oxide (NO), have been shown to differentially alter the Ca2+ sensitivity of the contractile apparatus of fast-twitch skeletal muscle, leading to the proposal that normal muscl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e91abc8ce01bcfd0b4185cfa5315800b
https://doi.org/10.1152/ajpcell.00251.2008
https://doi.org/10.1152/ajpcell.00251.2008
Autor:
G. S. Posterino, Stacey Leanne Dunn
Publikováno v:
American Journal of Physiology-Cell Physiology. 294:C97-C105
We compared the effects of 50 mM Pion caffeine-induced Ca2+release in mechanically skinned fast-twitch (FT) and slow-twitch (ST) skeletal muscle fibers of the rat. The time integral (area) of the caffeine response was reduced by ∼57% (FT) and ∼27
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2765760e6369d1ba536e1fa552d6cb01
https://doi.org/10.1152/ajpcell.00155.2007
https://doi.org/10.1152/ajpcell.00155.2007
Publikováno v:
PLoS ONE
PLoS ONE, Vol 10, Iss 9, p e0138388 (2015)
PLoS ONE, Vol 10, Iss 9, p e0138388 (2015)
Intrauterine growth restriction (IUGR), defined as a birth weight below the 10th centile, may be caused by maternal under nutrition, with evidence that IUGR offspring have an increased risk of cardiovascular disease (CVD) in adulthood. Calcium ions (
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ab2aa0d43ad242aadfecf114d328aaf3
https://hdl.handle.net/11541.2/116804
https://hdl.handle.net/11541.2/116804
Publikováno v:
Physiological Reports
Suramin has long been used in the treatment of various human diseases. Intravenous infusions of Suramin are commonly administered to patients over extended periods of time but there are a number of significant contraindications with peripheral muscle
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::13903c0bf53806ab8a7270eaedc3be1e
https://doi.org/10.14814/phy2.13333
https://doi.org/10.14814/phy2.13333