Zobrazeno 1 - 10
of 102
pro vyhledávání: '"G. S. Mcknight"'
Autor:
Linda C. Enns, John F. Morton, Piper R. Treuting, Mary J. Emond, Norman S. Wolf, Dao-Fu Dai, G. S. McKnight, Peter S. Rabinovitch, Warren C. Ladiges
Publikováno v:
PLoS ONE, Vol 5, Iss 2 (2010)
Externí odkaz:
https://doaj.org/article/86025f9260564cd99b08e290c1b8d1dd
Autor:
Merle L. Gilbert, Haifeng Yin, Benjamin M.L. Drum, Lei Li, Jing Li, G S McKnight, Xiaoyun Guo, Stephen W. Luckey, Yi Chen, Luis Fernando Santana, John D. Scott, Qinghang Liu
Publikováno v:
Circulation Research. 119
Impaired Ca 2+ cycling and myocyte contractility are a hallmark of heart failure triggered by pathological stress such as hemodynamic overload. The A-Kinase anchoring protein AKAP150 has been shown to coordinate key aspects of adrenergic regulation o
Autor:
G. S. McKnight, Elisenda Sanz, Jennifer D. Deem, Robert A. Steiner, Richard D. Palmiter, Albert Quintana
Publikováno v:
The Journal of neuroscience : the official journal of the Society for Neuroscience. 35(14)
Hypothalamic neuronal populations are central regulators of energy homeostasis and reproductive function. However, the ontogeny of these critical hypothalamic neuronal populations is largely unknown. We developed a novel approach to examine the devel
Autor:
M. J. Singer, Kenneth H. Fischbeck, Chris Clegg, Kenneth R. Peterson, R. S. Chmelar, D. Moore, K. Chen, G. Jeng, Barbara J. Trask, A. R. La Spada, M. E. McClain, S. A. Meadows, H. A. Haugen, G. S. McKnight
Publikováno v:
Human Molecular Genetics. 7:959-967
X-linked spinal and bulbar muscular atrophy (SBMA) is caused by a CAG repeat expansion in the first exon of the androgen receptor (AR) gene. Disease-associated alleles (37-66 CAGs) change in length when transmitted from parents to offspring, with a s
Autor:
Barry D. Johnson, Kimberly A. Burton, Todd Scheuer, Z. E. Hausken, John D. Scott, Ruth E. Westenbroek, William A. Catterall, Rejean L. Idzerda, G S McKnight
Publikováno v:
Proceedings of the National Academy of Sciences. 94:11067-11072
Preferential phosphorylation of specific proteins by cAMP-dependent protein kinase (PKA) may be mediated in part by the anchoring of PKA to a family of A-kinase anchor proteins (AKAPs) positioned in close proximity to target proteins. This interactio
Autor:
Bjørn Tore Gjertsen, G S McKnight, Hans G. Genieser, Gunnar Mellgren, Stein Ove Døskeland, Bernd Jastorff, A.D. Otten, Erik Maronde, Olav Karsten Vintermyr
Publikováno v:
Journal of Biological Chemistry. 270:20599-20607
Novel (Rp)-cAMPS analogs differed widely in ability to antagonize cAMP activation of pure cAMP-dependent protein kinase I and II and to antagonize actions of cAMP on gene expression, shape change, apoptosis, DNA replication, and protein phosphorylati
Publikováno v:
Current Biology. 5(6):625-634
Publikováno v:
Molecular and Cellular Biology. 14:6107-6116
Phosphorylation of CREB (cyclic AMP [cAMP]- response element [CRE]-binding protein) by cAMP-dependent protein kinase (PKA) leads to the activation of many promoters containing CREs. In neurons and other cell types, CREB phosphorylation and activation
Publikováno v:
Molecular and Cellular Biology. 13:7666-7676
The gene for the iron-binding protein transferrin is transcribed at a high level in liver hepatocytes but is also active in several other cell types, including oligodendrocytes in the brain. Enhancer elements between bp -560 and -44 of the transferri
Publikováno v:
Journal of Biological Chemistry. 268:6843-6846
Three amino acids were identified in the catalytic (C) subunit of the cyclic AMP-dependent protein kinase that are involved in interaction with regulatory (R) subunit, but not with the specific protein kinase inhibitor, PKI. In a functional assay for