Zobrazeno 1 - 5
of 5
pro vyhledávání: '"G. S. MacColl"'
Publikováno v:
Journal of Endocrinology. 176:293-304
GnRH and sex steroids play an important role in immune system modulation and development. GnRH and the GnRH receptor are produced locally by immune cells, suggesting an autocrine role for GnRH. Experimental studies show a stimulatory action of exogen
Publikováno v:
Journal of Endocrinology. 162:1-9
Gene transfer into muscle tissue is currently being developed as a method for the production, secretion and delivery of therapeutic proteins. This methodology has been used to produce a variety of physiologically active proteins and may ultimately be
Autor:
P.-M. G. Bouloux, Leticia Ferreira Gontijo Silveira, Paul M. Stewart, M. Thomas, G. S. MacColl, Duncan A. Clark
Publikováno v:
The Journal of clinical endocrinology and metabolism. 87(6)
Mutations in the GnRH receptor (GnRHR) have been shown to be responsible for a significant number of autosomic recessive and, less commonly, sporadic cases of idiopathic hypogonadotropic hypogonadism. We describe a woman with complete GnRH resistance
Idiopathic gonadotrophin deficiency: genetic questions addressed through phenotypic characterization
Autor:
R, Quinton, V M, Duke, A, Robertson, J M, Kirk, G, Matfin, P A, de Zoysa, C, Azcona, G S, MacColl, H S, Jacobs, G S, Conway, M, Besser, R G, Stanhope, P M, Bouloux
Publikováno v:
Clinical endocrinology. 55(2)
The association of idiopathic hypogonadotrophic hypogonadism (IHH) with congenital olfactory deficit defines Kallmann's syndrome (KS). Although a small proportion of IHH patients have been found to harbour defined genetic lesions, the genetic basis o
Autor:
G. S. Maccoll, Francisco J. Novo, Geoffrey Goldspink, P. M. G. Bouloux, N. J. Marshall, Michael J. Waters
Publikováno v:
The Journal of endocrinology. 165(2)
The production of peptide hormones by skeletal muscle tissue is a promising area of gene therapy. Skeletal muscle myogenesis can be induced in vitro, resulting in the fusion of mononucleate myoblasts to form multinucleate myotubes, and delivery vecto