Zobrazeno 1 - 10
of 27
pro vyhledávání: '"G. S. Dean"'
Publikováno v:
Vaccine. 32:5839-5844
There is an urgent need to identify additional diagnostic biomarkers for bovine TB to complement existing read-out systems such as interferon-gamma and for predictive markers of vaccine efficacy to accelerate vaccine development. To evaluate the pote
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1b2ba384f1bbe299c0a6c637867aa475
https://doi.org/10.1016/j.vaccine.2014.07.034
https://doi.org/10.1016/j.vaccine.2014.07.034
Autor:
Derek Clifford, Bernardo Villarreal-Ramos, Martin Vordermeier, Zhou Xing, Francisco J. Salguero, R. G. Hewinson, Helen McShane, Adam O. Whelan, Sarah C. Gilbert, G. S. Dean
There is a requirement for vaccines or vaccination strategies that confer better protection against TB than the current live attenuated Mycobacterium bovis Bacillus Calmette-Guerin (BCG) vaccine for use in cattle. Boosting with recombinant viral vect
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fc60789ccf2636dcc3488022c2f76ac3
https://ora.ox.ac.uk/objects/uuid:5b4a505d-314c-44f3-aca4-ce352d1a7abe
https://ora.ox.ac.uk/objects/uuid:5b4a505d-314c-44f3-aca4-ce352d1a7abe
Autor:
Philip J. Hogarth, G. S. Dean, Ida Rosenkrands, R. G. Hewinson, H. M. Vordermeier, Else Marie Agger, Peter Andersen, Daryan A. Kaveh
Publikováno v:
ResearcherID
Tuberculosis (TB) remains one of the most important infectious diseases of humans and animals. Mycobacterium bovis BCG, the only currently available TB vaccine, demonstrates variable levels of efficacy; therefore, a replacement or supplement to BCG i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8fc6507095822d695d8a6b6268e36c48
https://doi.org/10.1128/cvi.00229-09
https://doi.org/10.1128/cvi.00229-09
Autor:
E. Mead, Paul R. Wheeler, B. Villareal-Ramos, H. M. Vordermeier, Shelley G. Rhodes, Linda K. Johnson, Derek Clifford, Adam O. Whelan, Michael Coad, R. G. Hewinson, G. S. Dean
Publikováno v:
Tuberculosis. 88:586-594
Cattle infected with Mycobacterium bovis spoligotype 9 were treated with Isoniazid (INH) from three to 14 weeks post infection, rested for fourweeks to allow INH depletion and then challenged with M. bovis spoligotype 35. Post mortem examination (PME
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::43f6705fee23199ed0b379e8a71bfb18
https://doi.org/10.1016/j.tube.2008.01.004
https://doi.org/10.1016/j.tube.2008.01.004
Autor:
Martin Vordermeier, G. S. Dean, Shelley G. Rhodes, Glyn Hewinson, Linda K. Johnson, Arun Wangoo
Publikováno v:
Tuberculosis. 87:71-76
To understand the relevance of aerogenic transmission for bovine tuberculosis, it is important to study cattle experimentally infected with low doses of Mycobacterium bovis that result in pathology of the lower respiratory tract resembling that of mo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d3276d563e0b1cdee268fd4997c92786
https://doi.org/10.1016/j.tube.2006.04.002
https://doi.org/10.1016/j.tube.2006.04.002
Autor:
Derek Clifford, Bernardo Villarreal-Ramos, G. S. Dean, Zhou Xing, Francisco J. Salguero, Peter C. L. Beverley, Adam O. Whelan, Elma Tchilian, H. M. Vordermeier
Publikováno v:
PLoS ONE, Vol 10, Iss 11, p e0142270 (2015)
PLoS ONE
PLoS ONE
The incidence of bovine tuberculosis (bTB) in the GB has been increasing since the 1980s. Immunisation, alongside current control measures, has been proposed as a sustainable measure to control bTB. Immunisation with Mycobacterium bovis bacillus Calm
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::871ed006fd865b784599b0b58c0437b0
http://europepmc.org/articles/PMC4636221?pdf=render
http://europepmc.org/articles/PMC4636221?pdf=render
Autor:
Nilu Goonetilleke, Adrian V. S. Hill, Sarah C. Gilbert, Shelley G. Rhodes, G. S. Dean, H. Martin Vordermeier, R. Glyn Hewinson, Kris Huygen
Publikováno v:
Immunology. 112:461-470
The development of novel vaccine strategies to replace or supplement bacille Calmette-Guérin (BCG) is urgently required. Here we study, in cattle, the use of heterologous prime-boost strategies based on vaccination with BCG and the mycobacterial myc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6992520ce37b9ce04001036be91b4316
https://doi.org/10.1111/j.1365-2567.2004.01903.x
https://doi.org/10.1111/j.1365-2567.2004.01903.x
Publikováno v:
Lupus. 11:493-500
Systemic lupus erythematosus (SLE) is characterized by B cell hyperactivity and the production of autoantibodies, some of which (antibodies to dsDNA) are thought to be pathogenic. T helper cells drive the production of autoantibodies and the aim of t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8dc569d3373cc1e317fd248a05a3b716
https://doi.org/10.1191/0961203302lu235oa
https://doi.org/10.1191/0961203302lu235oa
Autor:
Sarah C. Gilbert, Bernardo Villarreal-Ramos, H. M. Vordermeier, R. G. Hewinson, G. S. Dean, Derek Clifford, Helen McShane
Publikováno v:
Veterinary Immunology and Immunopathology. 158(3-4)
BCG is used experimentally as a vaccine against tuberculosis (TB), induced by Mycobacterium bovis, in cattle (bTB). However, the efficacy of BCG is variable in humans, cattle and guinea pigs. An adenoviral vector expressing Antigen 85A (Ad5Ag85A) has
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::14918ccb54d2bd0701f48f476ff395c5
http://ora.ox.ac.uk/objects/uuid:54e6af8c-53c7-458e-997b-dc8a129adae7
http://ora.ox.ac.uk/objects/uuid:54e6af8c-53c7-458e-997b-dc8a129adae7
Publikováno v:
Annals of the Rheumatic Diseases. 59:243-251
SLE is an autoimmune rheumatic disease that principally affects women in the childbearing years.1 The prevalence of SLE varies between ethnic groups, being approximately 1:250 among black women, 1:1000 in Chinese women and 1:4300 in white women. SLE
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b537c84f9d8c79795f7b943e807ae584
https://doi.org/10.1136/ard.59.4.243
https://doi.org/10.1136/ard.59.4.243