Výsledky vyhledávání - "G. S. Chhatwal"

Conserved anchorless surface proteins as group A streptococcal vaccine candidates

Autor: Jason N. Cole, Marcus Fulde, Bostjan Kobe, Anna Henningham, Emiliano Chiarot, K.S. Sriprakash, Amanda J. Cork, Immaculada Margarit, Graham Magor, Steven P. Djordjevic, Stuart J. Cordwell, Manfred Rohde, Mark J. Walker, Victor Nizet, Christine M. Gillen, Jon Hartas, Michael R. Batzloff, G. S. Chhatwal, Vidiya Ramachandran

Publikováno v: Journal of Molecular Medicine. 90:1197-1207

Streptococcus pyogenes (group A Streptococcus (GAS)) causes ∼700 million human infections each year, resulting in over 500,000 deaths. The development of a commercial GAS vaccine is hampered by the occurrence of many unique GAS serotypes, antigenic

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::794ab20132697185aac3a96d6366ebc3
https://doi.org/10.1007/s00109-012-0897-9

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Quantitative Bestimmungen der Immunglobulin G-Bindungen an Streptokokken1

Autor: G. S. Chhatwal, Hans Blobel, F. Gomes Ferreira Lima

Publikováno v: Zentralblatt für Veterinärmedizin Reihe B. 32:213-219

Zusammenfassung Jeweils 6 Kulturen von Streptococcus pyogenes vom Menschen, Sc. dysgalactiae vom Rind, Sc. equisimilis vom Menschen und Sc. equisimilis vom Pferd wurden aufgrund ihrer deutlichen Fc-Rezeptoraktivitat fur Immunglobulin (Ig)G vom Mensch

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::a30fff05e0d3796379003db49b21d58d
https://doi.org/10.1111/j.1439-0450.1985.tb01958.x

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M protein‐mediated plasminogen binding is essential for the virulence of an invasiveStreptococcus pyogenesisolate

Autor: Jason D. McArthur, Katrin Dinkla, Mark J. Walker, G. S. Chhatwal, Martina L. Sanderson-Smith, Amanda J. Cork, Jason N. Cole, Peter G. Maamary

Publikováno v: The FASEB Journal. 22:2715-2722

The human protease plasmin plays a crucial role in the capacity of the group A streptococcus (GAS; Streptococcus pyogenes) to initiate invasive disease. The GAS strain NS88.2 was isolated from a case of bacteremia from the Northern Territory of Austr

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::610a7f5a8345745b177c485399e91360
https://doi.org/10.1096/fj.07-105643

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Virulence gene profiling of GAS isolates from the Netherlands

Autor: David J. McMillan, W. Wannet, Robert Geffers, B.J.M. Vlaminckx, K.S. Sriprakash, G. S. Chhatwal, L.M. Schouls

Publikováno v: International Congress Series. 1289:180-183

We have constructed a targeted GAS virulence array containing 228 group A streptococcal genes. Using this array we profiled the virulence gene repertoire of 45 GAS isolates from The Netherlands. Cluster analysis of the array data for these strains su

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::82db9665d726bfa7b493947d1ac881ba
https://doi.org/10.1016/j.ics.2005.11.058

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Intranasal Vaccination with Streptococcal Fibronectin Binding Protein Sfb1 Fails To Prevent Growth and Dissemination ofStreptococcus pyogenesin a Murine Skin Infection Model

Autor: Kadaba S. Sriprakash, James Chin, Jason D. McArthur, Mark J. Walker, Susanne R. Talay, Bart J. Currie, Eva Medina, G. S. Chhatwal, A. Mueller

Publikováno v: Infection and Immunity. 72:7342-7345

Fibronectin binding protein F1 (Sfb1) ofStreptococcus pyogenes(group A streptococcus [GAS]) is a well-characterized adhesin that has been shown to induce protection in mice against a lethal intranasal GAS challenge after intranasal immunization with

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::52e271af937036813c19342a98aa9096
https://doi.org/10.1128/iai.72.12.7342-7345.2004

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Trigger for group A streptococcal M1T1 invasive disease

Autor: Jason N. Cole, Jason D. Mcarthur, Fiona C. Mckay, Martina L. Sanderson-Smith, Amanda J. Cork, Marie Ranson, Manfred Rohde, Andreas Itzek, Hongmin Sun, David Ginsburg, Malak Kotb, Victor Nizet, G. S. Chhatwal, Mark J. Walker

Publikováno v: FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 20(10)

The globally disseminated Streptococcus pyogenes M1T1 clone causes a number of highly invasive human diseases. The transition from local to systemic infection occurs by an unknown mechanism; however invasive M1T1 clinical isolates are known to expres

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4c13359c351b989bbbe195608aaa20e1
https://pubmed.ncbi.nlm.nih.gov/16790522

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Genes for the majority of group a streptococcal virulence factors and extracellular surface proteins do not confer an increased propensity to cause invasive disease

Autor: B.J.M. Vlaminckx, G. S. Chhatwal, Kadaba S. Sriprakash, David J. McMillan, Wim J B Wannet, Jan Buer, Robert G. Beiko, Robert Geffers, Leo M Schouls

Publikováno v: Clinical infectious diseases : an official publication of the Infectious Diseases Society of America. 43(7)

Background. The factors behind the reemergence of severe, invasive group A streptococcal (GAS) diseases are unclear, but it could be caused by altered genetic endowment in these organisms. However, data from previous studies assessing the association

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::959a83773bf19f177ac3d3c2d4915f41
https://pubmed.ncbi.nlm.nih.gov/16941370

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