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pro vyhledávání: '"G. S. Chhatwal"'
Akademický článek
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Autor:
Anna C. Seale, Steven Y. C. Tong, Jonathan R. Carapetis, Ankur Mutreja, David Price, James A. Berkley, Pierre R. Smeesters, Stephen D. Bentley, Sebastián Duchêne, John A. Lees, Hannah R Frost, Kate A. Worthing, Matthew T. G. Holden, Philip M. Giffard, Bart J. Currie, John D. Fraser, Olga Berking, Allan Saul, Mark J. Walker, Richard A. Strugnell, Nicole J. Moreland, Simon R. Harris, Julian Parkhill, Rebecca J. Towers, Deborah A Williamson, Amanda J. Cork, Gordon Dougan, Tania Rivera-Hernandez, Jake A. Lacey, Liam McIntyre, G. S. Chhatwal, Trevor Lithgow, Andrew C Steer, René Bergmann, Patric Nitsche-Schmitz, Mark R. Davies, Rosângela Stadnick Lauth de Almeida Torres, Sophia David
Publikováno v:
Nature genetics, 51 (6
Nature genetics
United Kingdom
United States
Nature genetics
United Kingdom
United States
Group A Streptococcus (GAS; Streptococcus pyogenes) is a bacterial pathogen for which a commercial vaccine for humans is not available. Employing the advantages of high-throughput DNA sequencing technology to vaccine design, we have analyzed 2,083 gl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ebe231f38a440c1b55c598477636bc04
https://www.repository.cam.ac.uk/handle/1810/316646
https://www.repository.cam.ac.uk/handle/1810/316646
Autor:
Matthew T. G. Holden, Allan Saul, Sophia David, Liam McIntyre, Jonathan R. Carapetis, Pierre R. Smeesters, Nicole J. Moreland, René Bergmann, John D. Fraser, Simon R. Harris, Amanda J. Cork, Trevor Lithgow, John A. Lees, Patric Nitsche-Schmitz, Kate A. Worthing, G. S. Chhatwal, Ankur Mutreja, Julian Parkhill, Mark R. Davies, Rosângela Stadnick Lauth de Almeida Torres, Steven Y. C. Tong, James A. Berkley, Deborah A Williamson, Philip M. Giffard, Sebastián Duchêne, Andrew C Steer, Bart J. Currie, Anna C. Seale, Jake A. Lacey, Stephen D. Bentley, Tania Rivera-Hernandez, Mark J. Walker, David J. Price, Hannah R Frost, Richard A. Strugnell, Rebecca J. Towers, Olga Berking, Gordon Dougan
Publikováno v:
Nature Genetics. 51:1295-1295
Autor:
Jason N. Cole, Marcus Fulde, Bostjan Kobe, Anna Henningham, Emiliano Chiarot, K.S. Sriprakash, Amanda J. Cork, Immaculada Margarit, Graham Magor, Steven P. Djordjevic, Stuart J. Cordwell, Manfred Rohde, Mark J. Walker, Victor Nizet, Christine M. Gillen, Jon Hartas, Michael R. Batzloff, G. S. Chhatwal, Vidiya Ramachandran
Publikováno v:
Journal of Molecular Medicine. 90:1197-1207
Streptococcus pyogenes (group A Streptococcus (GAS)) causes ∼700 million human infections each year, resulting in over 500,000 deaths. The development of a commercial GAS vaccine is hampered by the occurrence of many unique GAS serotypes, antigenic
Publikováno v:
Zentralblatt für Veterinärmedizin Reihe B. 32:213-219
Zusammenfassung Jeweils 6 Kulturen von Streptococcus pyogenes vom Menschen, Sc. dysgalactiae vom Rind, Sc. equisimilis vom Menschen und Sc. equisimilis vom Pferd wurden aufgrund ihrer deutlichen Fc-Rezeptoraktivitat fur Immunglobulin (Ig)G vom Mensch
Autor:
Jason D. McArthur, Katrin Dinkla, Mark J. Walker, G. S. Chhatwal, Martina L. Sanderson-Smith, Amanda J. Cork, Jason N. Cole, Peter G. Maamary
Publikováno v:
The FASEB Journal. 22:2715-2722
The human protease plasmin plays a crucial role in the capacity of the group A streptococcus (GAS; Streptococcus pyogenes) to initiate invasive disease. The GAS strain NS88.2 was isolated from a case of bacteremia from the Northern Territory of Austr
Autor:
David J. McMillan, W. Wannet, Robert Geffers, B.J.M. Vlaminckx, K.S. Sriprakash, G. S. Chhatwal, L.M. Schouls
Publikováno v:
International Congress Series. 1289:180-183
We have constructed a targeted GAS virulence array containing 228 group A streptococcal genes. Using this array we profiled the virulence gene repertoire of 45 GAS isolates from The Netherlands. Cluster analysis of the array data for these strains su
Autor:
Kadaba S. Sriprakash, James Chin, Jason D. McArthur, Mark J. Walker, Susanne R. Talay, Bart J. Currie, Eva Medina, G. S. Chhatwal, A. Mueller
Publikováno v:
Infection and Immunity. 72:7342-7345
Fibronectin binding protein F1 (Sfb1) ofStreptococcus pyogenes(group A streptococcus [GAS]) is a well-characterized adhesin that has been shown to induce protection in mice against a lethal intranasal GAS challenge after intranasal immunization with
Autor:
Jason N. Cole, Jason D. Mcarthur, Fiona C. Mckay, Martina L. Sanderson-Smith, Amanda J. Cork, Marie Ranson, Manfred Rohde, Andreas Itzek, Hongmin Sun, David Ginsburg, Malak Kotb, Victor Nizet, G. S. Chhatwal, Mark J. Walker
Publikováno v:
FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 20(10)
The globally disseminated Streptococcus pyogenes M1T1 clone causes a number of highly invasive human diseases. The transition from local to systemic infection occurs by an unknown mechanism; however invasive M1T1 clinical isolates are known to expres
Autor:
B.J.M. Vlaminckx, G. S. Chhatwal, Kadaba S. Sriprakash, David J. McMillan, Wim J B Wannet, Jan Buer, Robert G. Beiko, Robert Geffers, Leo M Schouls
Publikováno v:
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America. 43(7)
Background. The factors behind the reemergence of severe, invasive group A streptococcal (GAS) diseases are unclear, but it could be caused by altered genetic endowment in these organisms. However, data from previous studies assessing the association