Zobrazeno 1 - 10
of 281
pro vyhledávání: '"G. S. BISACCHI"'
Autor:
Cabua MC; CNRS, ICMMO, CP3A Organic Synthesis Group, Université Paris-Saclay, 17 Avenue des Sciences, 91400, Orsay, France.; Department of Chemical and Geological Science, University of Cagliari, S.P. No. 8 Km 0.700, 09042, Monserrato, Italy., He X; CNRS, ICMMO, CP3A Organic Synthesis Group, Université Paris-Saclay, 17 Avenue des Sciences, 91400, Orsay, France., Secci F; Department of Chemical and Geological Science, University of Cagliari, S.P. No. 8 Km 0.700, 09042, Monserrato, Italy., Deloisy S; CNRS, ICMMO, CP3A Organic Synthesis Group, Université Paris-Saclay, 17 Avenue des Sciences, 91400, Orsay, France., Aitken DJ; CNRS, ICMMO, CP3A Organic Synthesis Group, Université Paris-Saclay, 17 Avenue des Sciences, 91400, Orsay, France.
Publikováno v:
ChemistryOpen [ChemistryOpen] 2024 Oct 30, pp. e202400279. Date of Electronic Publication: 2024 Oct 30.
Autor:
J C, Barrish, E, Gordon, M, Alam, P F, Lin, G S, Bisacchi, P, Chen, P T, Cheng, A W, Fritz, J A, Greytok, M A, Hermsmeier
Publikováno v:
Journal of Medicinal Chemistry. 37:1758-1768
A series of HIV protease inhibitors containing a novel C2 symmetrical "aminodiol" core structure were prepared from amino acid starting materials. The ability of the aminodiols to inhibit HIV replication in cell culture is comparable to their ability
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a6c16485dea2c9eeb5bfd56c95a21e4a
https://doi.org/10.1021/jm00038a005
https://doi.org/10.1021/jm00038a005
Publikováno v:
Rasayan Journal of Chemistry. Jul-Sep2024, Vol. 17 Issue 3, p1222-1229. 8p.
Autor:
J. C. BARRISH, E. GORDON, M. ALAM, P.-F. LIN, G. S. BISACCHI, P. CHEN, P. T. W. CHENG, A. W. FRITZ, J. A. GREYTOK, M. A. HERMSMEIER, W. G. HUMPHREYS, K. A. LIS, M. A. MARELLA, Z. MERCHANT, T. MITT, R. A. MORRISON, M. T. OBERMEIER, J. PLUSCEC, M. SKOOG, W. A. SLUSARCHYK, S. H. SPERGEL, ET AL. ET AL.
Publikováno v:
ChemInform. 25
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a379ef29fcd1a56c154a90d2dea88858
https://doi.org/10.1002/chin.199444198
https://doi.org/10.1002/chin.199444198
Autor:
G. S. Bisacchi, Jack Z. Gougoutas, Robert Zahler, Janak Singh, Mary F. Malley, Richard H. Mueller, J. D. Jun. Godfrey, T. P. Kissick, J. D. Di Marco, T. Mitt
Publikováno v:
ChemInform. 26
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ff8eb78d4255f627692b43ab5ad7da02
https://doi.org/10.1002/chin.199537260
https://doi.org/10.1002/chin.199537260
Autor:
P. CHEN, P. T. W. CHENG, M. ALAM, B. D. BEYER, G. S. BISACCHI, T. DEJNEKA, A. J. EVANS, J. A. GREYTOK, M. A. HERMSMEIER, W. G. HUMPHREYS, G. A. JACOBS, O. KOCY, P.-F. LIN, K. A. LIS, M. A. MARELLA, D. E. RYONO, A. K. SHEAFFER, S. H. SPERGEL, C. SUN, J. A. TINO, G. VITE, R. J. COLONNO, ET AL. ET AL.
Publikováno v:
ChemInform. 27
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5ae70df843d6b519c078580f4f14b9f0
https://doi.org/10.1002/chin.199635200
https://doi.org/10.1002/chin.199635200
Autor:
Robert Zahler, Alain Martel, Richard J. Colonno, G. S. Bisacchi, O. Kocy, S. Innaimo, M. G. Young, Jean-Paul Daris, G. A. Jacobs, Sam T. Chao, Z. Merchant, William A. Slusarchyk, Joseph E. Sundeen, Philippe Lapointe, C. Bachard
Publikováno v:
ChemInform. 28
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5196cba329e4c401131ecdd8edf1eb7f
https://doi.org/10.1002/chin.199720199
https://doi.org/10.1002/chin.199720199
Autor:
Z. Merchant, S. Skwish, Dorothy Slusarchyk, P.J. McCann, D.A. Young, M. Morella, Kenneth E.J. Dickinson, Michael Cap, Ravindar N. Girotra, Anita D. Russell, B.E. Abboa-Offei, William N. Washburn, G.T. Allen, A.V. Gavai, Belay Tesfamariam, Peter T. W. Cheng, G. S. Bisacchi, Tammy C. Wang, A A Seymour, T.W. Harper, C.M. Arbeeny, Tamara Dejneka, Amarendra B. Mikkilineni, Poss Kathleen M, Chongqing Sun, Philip M. Sher, T.L. Waldron, R.J. George, B.H. Frohlich, Ginger Wu, Denis E. Ryono
Publikováno v:
Bioorganicmedicinal chemistry letters. 14(13)
A series of N-(4-hydroxy-3-methylsulfonanilidoethanol)arylglycinamides were prepared and evaluated for their human β3 adrenergic receptor agonist activity. SAR studies led to the identification of BMS-201620 (39), a potent β3 full agonist (Ki=93 nM
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8c4e6c1a53153c8278f43697b1fe4710
https://pubmed.ncbi.nlm.nih.gov/15177466
https://pubmed.ncbi.nlm.nih.gov/15177466
Autor:
Peter T. W. Cheng, Jill A. Greytok, Ping Chen, Chongqing Sun, William G. Humphreys, M. Alam, K. A. Lis, G. A. Jacobs, S. H. Spergel, A. J. Evans, M. A. Marella, P.-F. Lin, Amy K. Sheaffer, Mark A. Hermsmeier, Tamara Dejneka, G. S. Bisacchi, Gregory D. Vite, Robert Zahler, Richard J. Colonno, B. D. Beyer, Denis E. Ryono, Joel C. Barrish, O. Kocy, Joseph A. Tino
Publikováno v:
Journal of medicinal chemistry. 39(10)
A series of novel aminodiol inhibitors of HIV protease based on the lead compound 1 with structural modifications at P1' were synthesized in order to reduce the cytotoxicity of 1. We have observed a high degree of correlation between the lipophilicit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1cc030633e8057142d962c53b921c2e8
https://pubmed.ncbi.nlm.nih.gov/8642558
https://pubmed.ncbi.nlm.nih.gov/8642558
Autor:
G, Yamanaka, A V, Tuomari, M, Hagen, B, McGeever-Rubin, B, Terry, M, Haffey, G S, Bisacchi, A K, Field
Publikováno v:
Molecular pharmacology. 40(3)
The cycloburtane nucleoside analog (1R-1 alpha,2 beta,3 alpha)-9-[2,3-bis(hydroxymethyl)cyclobutyl]guanine [(R)-BHCG or SQ 34,514] was recently synthesized and shown to be the active enantiomer of (+/-)-BHCG (SQ 33,054), a potent inhibitor of several
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::515a0da2fc3a3b8a583983b71290112c
https://pubmed.ncbi.nlm.nih.gov/1896029
https://pubmed.ncbi.nlm.nih.gov/1896029