Zobrazeno 1 - 10
of 38
pro vyhledávání: '"G. Ryan Crislip"'
Publikováno v:
Physiological Reports, Vol 11, Iss 15, Pp n/a-n/a (2023)
Abstract Nitric oxide (NO) contributes to blood pressure (BP) regulation via its vasodilatory and anti‐inflammatory properties. We and others previously reported sex differences in BP in normotensive and hypertensive rat models where females have l
Externí odkaz:
https://doaj.org/article/52370cb3a48942ad92c9c1b5f1cdec7b
Autor:
Christopher A. Wolff, Miguel A. Gutierrez-Monreal, Lingsong Meng, Xiping Zhang, Lauren G. Douma, Hannah M. Costello, Collin M. Douglas, Elnaz Ebrahimi, Ann Pham, Aline C. Oliveira, Chunhua Fu, Amy Nguyen, Bryan R. Alava, Stuart J. Hesketh, Andrew R. Morris, Mehari M. Endale, G. Ryan Crislip, Kit-yan Cheng, Elizabeth A. Schroder, Brian P. Delisle, Andrew J. Bryant, Michelle L. Gumz, Zhiguang Huo, Andrew C. Liu, Karyn A. Esser
Publikováno v:
Cell Reports, Vol 42, Iss 1, Pp 111982- (2023)
Summary: Cellular circadian clocks direct a daily transcriptional program that supports homeostasis and resilience. Emerging evidence has demonstrated age-associated changes in circadian functions. To define age-dependent changes at the systems level
Externí odkaz:
https://doaj.org/article/2f18b4dcc2854c8b81ce1f23e09506dc
Autor:
Adrian Zietara, Denisha R. Spires, Alexandria Juffre, Hannah M. Costello, G. Ryan Crislip, Lauren G. Douma, Vladislav Levchenko, Lashodya V. Dissanayake, Christine A. Klemens, Oksana Nikolaienko, Aron M. Geurts, Michelle L. Gumz, Alexander Staruschenko
Publikováno v:
Hypertension (Dallas, Tex. : 1979). 79(11)
Background: Circadian rhythms play an essential role in physiological function. The molecular clock that underlies circadian physiological function consists of a core group of transcription factors, including the protein PER1 (Period1). Studies in mi
Autor:
Hannah M. Costello, Jermaine G. Johnston, Alexandria Juffre, G. Ryan Crislip, Michelle L. Gumz
Publikováno v:
Physiological Reviews. 102:1669-1701
An intrinsic cellular circadian clock is located in nearly every cell of the body. The peripheral circadian clocks within the cells of the kidney contribute to the regulation of a variety of renal processes. In this review, we summarize what is curre
Autor:
Hannah Costello, G. Ryan Crislip, Annalisse Mckee, Kit-Yan Cheng, Alexandria Juffre, Jermaine Johnstone, Lauren Douma, Michelle Gumz
Publikováno v:
Physiology. 38
Circadian rhythms are 24-hour oscillations that regulate many physiological functions including hormone signaling and electrolyte excretion. These rhythms are coordinated by a molecular clock, comprised of 4 key core clock proteins – BMAL1, CLOCK,
Autor:
Hannah Costello, Kit-Yan Cheng, Jermaine Johnstone, Alexandria Juffre, Lauren Douma, Michelle Gumz, G. Ryan Crislip
Publikováno v:
Physiology. 38
Clinical studies demonstrate that women have exacerbated salt-sensitive blood pressure (BP) responses compared to men. However, most studies examining the molecular mechanisms involved in salt-sensitive hypertension focus on males. Accumulating evide
Autor:
Hannah M Costello, G Ryan Crislip, Kit-Yan Cheng, I Jeanette Lynch, Alexandria Juffre, Phillip Bratanatawira, Annalisse Mckee, Ryanne S Thelwell, Victor M Mendez, Charles S Wingo, Lauren G Douma, Michelle L Gumz
Publikováno v:
Function. 4
Brain and muscle ARNT-like 1 (BMAL1) is a core circadian clock protein and transcription factor that regulates many physiological functions, including blood pressure (BP). Male global Bmal1 knockout (KO) mice exhibit ∼10 mmHg reduction in BP, as we
Autor:
G. Ryan Crislip, Jermaine G. Johnston, Lauren G. Douma, Hannah M. Costello, Alexandria Juffre, Kyla Boyd, Wendy Li, Cheoting C. Maugans, Miguel Gutierrez‐Monreal, Karyn A. Esser, Andrew J. Bryant, Andrew C. Liu, Michelle L. Gumz
Publikováno v:
Comprehensive Physiology. :2769-2798
Nearly every system within the body contains an intrinsic cellular circadian clock. The circadian clock contributes to the regulation of a variety of homeostatic processes in mammals through the regulation of gene expression. Circadian disruption of
Autor:
Hannah M. Costello, Alexandria Juffre, Kit-Yan Cheng, Phillip Bratanatawira, G. Ryan Crislip, Adrian Zietara, Denisha R. Spires, Alexander Staruschenko, Lauren G. Douma, Michelle L. Gumz
Publikováno v:
Canadian journal of physiology and pharmacology.
Endothelin-1 (ET-1) is a peptide hormone that acts on its receptors to regulate sodium handling in the kidney's collecting duct. Dysregulation of the endothelin axis is associated with various diseases, including salt-sensitive hypertension and chron
Autor:
Ivory Ellis, Michelle L. Gumz, Adam C. Stowie, G. Ryan Crislip, Oscar Castanon-Cervantes, Atlantis Hill, Anne Ramsey, Alec J. Davidson
Publikováno v:
Am J Physiol Renal Physiol
Nontraditional work schedules, such as shift work, have been associated with numerous health issues, including cardiovascular and metabolic disease. These work schedules can chronically misalign environmental timing cues with internal circadian clock