Zobrazeno 1 - 10
of 51
pro vyhledávání: '"G. Rucci"'
Autor:
E C, Henry, A S, Kende, G, Rucci, M J, Totleben, J J, Willey, S D, Dertinger, R S, Pollenz, J P, Jones, T A, Gasiewicz
Publikováno v:
Molecular pharmacology. 55(4)
Previous analyses suggested that potent aryl hydrocarbon receptor (AhR) antagonists were planar, with a lateral electron-rich center. To further define structural requirements and mechanism for antagonism, ten additional flavone derivatives were synt
Publikováno v:
Molecular pharmacology. 46(6)
The aryl hydrocarbon receptor (AhR) is a transcriptional enhancer that is activated by the binding of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) and related toxic xenobiotics, as well as some naturally occurring compounds. Ligand binding initiates 1)
Akademický článek
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Publikováno v:
Journal of Organometallic Chemistry. 117:285-295
Treatment of triphenylphosphine with bis(cycloocta-1,5-diene)nickel(0) in toluene followed by addition of benzonitrile gave two nickel(O) complexes. When the nickel/phosphine ratio was 1 : 3 the (benzonitrile)tris(triphenylphosphorane)- nickel(0) com
Publikováno v:
Journal of Organometallic Chemistry. 144:225-237
The preparation and the chemical properties of the clathrate compound tetrakis[(benzonitrile)(triphenylphosphorane)nickel(0)] · 2 toluene · ~1 n-hexane · ~1 cycloocta-1,5-diene are described. The crystal and molecular structure of this compound we
Akademický článek
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Autor:
C, Henry E, S, Kende A, G, Rucci, J, Totleben M, J, Willey J, D, Dertinger S, S, Pollenz R, P, Jones J, A, Gasiewicz T
Publikováno v:
Molecular Pharmacology; April 1999, Vol. 55 Issue: 4 p716-25, 10p
Publikováno v:
Drug metabolism and disposition: the biological fate of chemicals. 11(5)
The strains of mice, C57BL/6J, DBA/2J, and B6D2F1/J, have been used as models to study the mechanism of action of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD). The distribution, excretion, and metabolism of this compound was studied in male C57BL/6J, D
Publikováno v:
Biochemical pharmacology. 35(16)
The temporal and dose-related characteristics of hepatic enzymes induced in the hamster by 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) were examined. Male Syrian golden hamsters received a single intraperitoneal injection of TCDD at a dose of 0-500 mi
Autor:
T A, Gasiewicz, G, Rucci
Publikováno v:
Molecular pharmacology. 26(1)
The presence and properties of the Ah receptor were examined in the guinea pig, rat, hamster, monkey, and three different strains of mice. These species and strains have demonstrated differences in sensitivity and variability of response to 2,3,7,8-t