Zobrazeno 1 - 10
of 397
pro vyhledávání: '"G. Rayner"'
Autor:
Xiao Zhang, Mark Blaxter, Jonathan M. D. Wood, Alan Tracey, Shane McCarthy, Peter Thorpe, Jack G. Rayner, Shangzhe Zhang, Kirstin L. Sikkink, Susan L. Balenger, Nathan W. Bailey
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-19 (2024)
Abstract Theory predicts that compensatory genetic changes reduce negative indirect effects of selected variants during adaptive evolution, but evidence is scarce. Here, we test this in a wild population of Hawaiian crickets using temporal genomics a
Externí odkaz:
https://doaj.org/article/027ccb72b85d440983edc290e9c4aac9
Autor:
Laura J. Oppegard, Lia M. Barros, Hongyang Pi, James Kornfield, Catherine L. Hough, Samuel G. Rayner, Jeffrey C. Robinson, Peter J. Leary
Publikováno v:
Pulmonary Circulation, Vol 13, Iss 4, Pp n/a-n/a (2023)
Abstract Relationships between obesity and outcomes in pulmonary arterial hypertension (PAH) are complex. Previous work suggested obesity, occurring alongside PAH, may be associated with better survival. In our work, we suggest obesity prior to PAH d
Externí odkaz:
https://doaj.org/article/f2206ed90ff84df0a67580f8a64e7c59
Autor:
Nathan W. Bailey, Camille Desjonquères, Ana Drago, Jack G. Rayner, Samantha L. Sturiale, Xiao Zhang
Publikováno v:
Evolution Letters, Vol 5, Iss 5, Pp 444-457 (2021)
Abstract There is tantalizing evidence that phenotypic plasticity can buffer novel, adaptive genetic variants long enough to permit their evolutionary spread, and this process is often invoked in explanations for rapid adaptive evolution. However, th
Externí odkaz:
https://doaj.org/article/f31a164fdfd54961bca7efbe0b320fe9
Autor:
Hongyang Pi, Selma D. Carlson, Lia M. Barros, Laurie Hogl, James N. Kirkpatrick, Stephanie Nolley, David D. Ralph, Samuel G. Rayner, Peter J. Leary
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 11, Iss 14 (2022)
Externí odkaz:
https://doaj.org/article/fca6c292617447b2a36869150c16611b
Autor:
Zachary L Steinberg, Hongyang Pi, Samuel G Rayner, David D Ralph, Stephanie Nolley, Lia M Barros, Peter J Leary
Publikováno v:
BMJ Open Respiratory Research, Vol 9, Iss 1 (2022)
Introduction Pulmonary arterial hypertension (PAH) remains a serious and life-threatening illness. Thyroid dysfunction is relatively understudied in individuals with PAH but is known to affect cardiac function and vascular tone in other diseases. The
Externí odkaz:
https://doaj.org/article/cfb00c1ffa814c11916c4c5ab493051b
Autor:
Yoon Jung Choi, Adam M. Heck, Brian J. Hayes, Daniel Lih, Samuel G. Rayner, Brandon Hadland, Ying Zheng
Publikováno v:
Stem Cell Research & Therapy, Vol 12, Iss 1, Pp 1-10 (2021)
Abstract The human fetal liver is a critical organ for prenatal hematopoiesis, the study of which offers insights into niche signals that regulate the fates of hematopoietic stem and progenitor cells (HSPCs) during fetal development. Here, we demonst
Externí odkaz:
https://doaj.org/article/7f8f2a25dadc43d59ce34ae1926483f8
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-15 (2021)
Gene flow is classically thought to impede local adaptation via parallel evolution. However, a genomic study on Hawaiian crickets from different island populations finds evidence of parallel adaptation to the same lethal parasitoid in spite of strong
Externí odkaz:
https://doaj.org/article/14e117cdaadd486db32787ad59ac3ab8
Autor:
Sonia Pascoal, Judith E. Risse, Xiao Zhang, Mark Blaxter, Timothee Cezard, Richard J. Challis, Karim Gharbi, John Hunt, Sujai Kumar, Emma Langan, Xuan Liu, Jack G. Rayner, Michael G. Ritchie, Basten L. Snoek, Urmi Trivedi, Nathan W. Bailey
Publikováno v:
Evolution Letters, Vol 4, Iss 1, Pp 19-33 (2020)
Abstract Evolutionary adaptation is generally thought to occur through incremental mutational steps, but large mutational leaps can occur during its early stages. These are challenging to study in nature due to the difficulty of observing new genetic
Externí odkaz:
https://doaj.org/article/195f5b157407430f9140b6a31bb60cb8
Publikováno v:
Annals of the American Thoracic Society. 19:1925-1929
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c14cae13ef1eb678b07539b81f42c125
https://doi.org/10.1513/annalsats.202202-167cc
https://doi.org/10.1513/annalsats.202202-167cc
Endothelial‐derived von Willebrand factor accelerates fibrin clotting within engineered microvessels
Autor:
Samuel G. Rayner, Zackary Scholl, Christian J. Mandrycky, Junmei Chen, Karina N. LaValley, Peter J. Leary, William A. Altemeier, W. Conrad Liles, Dominic W. Chung, José A. López, Hongxia Fu, Ying Zheng
Publikováno v:
Journal of Thrombosis and Haemostasis. 20:1627-1637
Von Willebrand factor (VWF) is classically associated with primary hemostasis and platelet-rich arterial thromboses, but recently has also been implicated in fibrin clotting and venous thrombosis. Direct interaction between fibrin and VWF may mediate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::be0352ddba812b016263495325cee14b
https://doi.org/10.1111/jth.15714
https://doi.org/10.1111/jth.15714