Zobrazeno 1 - 10
of 451
pro vyhledávání: '"G. RODNEY"'
Autor:
Lathan Lucas, Larissa Nitschke, Brandon Nguyen, James A. Loehr, George G. Rodney, Thomas A. Cooper
Publikováno v:
iScience, Vol 27, Iss 11, Pp 111104- (2024)
Summary: Skeletal muscle cells (myofibers) are elongated non-mitotic, multinucleated syncytia that have adapted a microtubule lattice. Microtubule-associated proteins (MAPs) play roles in regulating microtubule architecture. The most abundant MAP in
Externí odkaz:
https://doaj.org/article/b97167ad0f6049e7a56278c345d0f1e0
Autor:
Chang Seok Lee, Sung Yun Jung, Rachel Sue Zhen Yee, Nadia H. Agha, Jin Hong, Ting Chang, Lyle W. Babcock, Jorie D. Fleischman, Benjamin Clayton, Amy D. Hanna, Christopher S. Ward, Denise Lanza, Ayrea E. Hurley, Pumin Zhang, Xander H. T. Wehrens, William R. Lagor, George G. Rodney, Susan L. Hamilton
Publikováno v:
Communications Biology, Vol 6, Iss 1, Pp 1-19 (2023)
Abstract Here we show that striated muscle preferentially expressed protein kinase α (Spegα) maintains cardiac function in hearts with Spegβ deficiency. Speg is required for stability of excitation-contraction coupling (ECC) complexes and interact
Externí odkaz:
https://doaj.org/article/7a8ed53a9dd64509bc4efd890aaae296
Autor:
James B. Unger, G. Rodney Meeks
Publikováno v:
Revista Colombiana de Obstetricia y Ginecología, Vol 48, Iss 1 (1997)
Objetivos: Detenninar el número de mujeres a quienes se les practica histerectomía después de la ablación endometrial y las indicaciones para la cirugía subsecuente. Diseño del estudio: Se practicó ablación endometrial con esfera a 42 mujeres
Externí odkaz:
https://doaj.org/article/94508807328a47fbae43c9c4c4a7cc6a
Autor:
James Anthony Loehr, Shang Wang, Tanya R Cully, Rituraj Pal, Irina V Larina, Kirill V Larin, George G Rodney
Publikováno v:
eLife, Vol 11 (2022)
Externí odkaz:
https://doaj.org/article/0d8404561d0645fdad5e36648483aa2f
Autor:
John T. Olthoff, Angus Lindsay, Reem Abo-Zahrah, Kristen A. Baltgalvis, Xiaobai Patrinostro, Joseph J. Belanto, Dae-Yeul Yu, Benjamin J. Perrin, Daniel J. Garry, George G. Rodney, Dawn A. Lowe, James M. Ervasti
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-14 (2018)
In the mdx mouse model of Duchenne muscular dystrophy, muscle contractions lead to force loss, which is attributed to myofibre damage. Here, the authors show that force loss is instead mediated by a redox circuit involving NOX2, PROX1, myoglobin and
Externí odkaz:
https://doaj.org/article/223d776794074fb79b1d4e9d6b3d3b4f
Autor:
Rituraj Pal, Michela Palmieri, Arindam Chaudhury, Tiemo Jürgen Klisch, Alberto di Ronza, Joel R. Neilson, George G. Rodney, Marco Sardiello
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-14 (2018)
The growth-promoting activity of mTORC1 is regulated by amino acid availability via the Rag GTPases. Here, the authors demonstrate Src-dependent control of cell size and autophagy through disruption of the Rag GTPase–GATOR1 complex and mTORC1 activ
Externí odkaz:
https://doaj.org/article/2878637528374367ad3c6859ef91cfca
Autor:
Eric Himelman, Julie Nouet, Mauricio A. Lillo, Alexander Chong, Delong Zhou, Xander H. T. Wehrens, George G. Rodney, Lai-Hua Xie, Natalia Shirokova, Jorge E. Contreras, Diego Fraidenraich
Publikováno v:
American Journal of Physiology-Heart and Circulatory Physiology. 323:H983-H995
Dilated cardiomyopathy is the leading cause of death in Duchenne muscular dystrophy (DMD), an inherited degenerative disease of the cardiac and skeletal muscle caused by absence of the protein dystrophin. We showed one hallmark of DMD cardiomyopathy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7a86255591c808805041d03090769303
https://doi.org/10.1152/ajpheart.00179.2022
https://doi.org/10.1152/ajpheart.00179.2022
Autor:
Thompson, G. Rodney
Publikováno v:
Eastern European Economics, 1999 Nov 01. 37(6), 35-53.
Externí odkaz:
https://www.jstor.org/stable/4380199
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-10 (2017)
Abstract Tuberous sclerosis (TS) is a multi-organ autosomal dominant disorder that is best characterized by neurodevelopmental deficits and the presence of benign tumors. TS pathology is caused by mutations in tuberous sclerosis complex (TSC) genes a
Externí odkaz:
https://doaj.org/article/a4d9a93f97c34c3c8f582aba8a8ebcdd
Autor:
Chang Seok Lee, Amy D. Hanna, Hui Wang, Adan Dagnino-Acosta, Aditya D. Joshi, Mark Knoblauch, Yan Xia, Dimitra K. Georgiou, Jianjun Xu, Cheng Long, Hisayuki Amano, Corey Reynolds, Keke Dong, John C. Martin, William R. Lagor, George G. Rodney, Ergun Sahin, Caroline Sewry, Susan L. Hamilton
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-15 (2017)
Mutations in the RyR1 channel cause core myopathies. Here the authors show that ER stress and the unfolded protein response underlie the pathology caused by a common RyR1 channel mutation, and show that treatment with a chemical chaperone restores mu
Externí odkaz:
https://doaj.org/article/8a7faf752203416684267602ebe0758b