Zobrazeno 1 - 6
of 6
pro vyhledávání: '"G. R. MacGregor"'
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 7
Our understanding of the molecular mechanisms that govern gene expression has been facilitated by the ability to introduce recombinant DNA molecules into heterologous cellular systems both in vitro and in vivo. One approach to defining DNA sequences
Autor:
G. R. MacGregor
Publikováno v:
Reproduction (Cambridge, England). 124(3)
Chimaeric analysis is a powerful method to address questions about the cell-autonomous nature of defects in spermatogenesis. Symplastic spermatids (sys) mice have a recessive mutation that causes male sterility due to an arrest in germ-cell developme
Autor:
L D, Russell, J, Warren, L, Debeljuk, L L, Richardson, P L, Mahar, K G, Waymire, S P, Amy, A J, Ross, G R, MacGregor
Publikováno v:
Biology of reproduction. 65(1)
Bclw is a death-protecting member of the Bcl2 family of apoptosis-regulating proteins. Mice that are mutant for Bclw display progressive and nearly complete testicular degeneration. We performed a morphometric evaluation of testicular histopathology
Publikováno v:
The International journal of developmental biology. 42(7)
It is difficult to study gene expression in mammalian embryonic germ cells as PGCs constitute only a minor proportion of the mouse embryo. We have overcome this problem by using a novel combination of established molecular and transgenic approaches.
Publikováno v:
Advances in experimental medicine and biology. 241
Autor:
Katrina G. Waymire, Chun Shi Lin, Fred N. Ross-Cisneros, Eric Sung, Grant R. MacGregor, Douglas C. Wallace, Mark S. Sharpley, Alfredo A. Sadun, Valerio Carelli, Billy X. Pan, Daniel W. Gil, Weiwei Fan, Meagan J. McManus, Peter Baciu
An animal model of Leber hereditary optic neuropathy (LHON) was produced by introducing the human optic atrophy mtDNA ND6 P25L mutation into the mouse. Mice with this mutation exhibited reduction in retinal function by elecroretinogram (ERG), age-rel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e597036b0610929c45a36ecd985c1d77
https://europepmc.org/articles/PMC3523873/
https://europepmc.org/articles/PMC3523873/