Zobrazeno 1 - 10
of 24
pro vyhledávání: '"G. R. Avant"'
Publikováno v:
Gastroenterology. 82:89-96
Cimetidine has been demonstrated to impair microsomal oxidative drug metabolism in a dose-dependent manner in an animal model. The inhibition has also been shown to be rapid, occurring after a single dose. In the present study we demonstrate that rec
Publikováno v:
Radiology. 141:311-316
Oral cholecystography following the ingestion of 4.5 g of sodium tyropanoate (Bilopaque) was performed in 1,053 patients. The radiographs of 89 patients in whom the gallbladder was either faintly visualized or nonvisualized were reviewed for the pres
Publikováno v:
Life Sciences. 24:1345-1350
Physostigmine (Antilirium R ) has been reported to reverse benzodiazepine- induced sleep or coma in man and prevent death in animals. Accordingly, we investigated the effect of Antilirium upon benzodiazepine binding to both rat and human brain. We re
Autor:
Wade W Sutton, Robert H Bergstrand, Raymond L. Woosley, H T Wolfenden, Ted Wang, G. R. Avant, Dan M. Roden, Grant R. Wilkinson, Lyle A. Siddoway, Alastair J. J. Wood
Publikováno v:
Clinical Pharmacology and Therapeutics. 40:148-154
The antiarrhythmic agent encainide undergoes extensive first-pass hepatic metabolism after oral dosing. The active metabolites O-desmethylencainide and 3-methoxy-O-desmethylencainide are formed in subjects who are extensive metabolizers (EMs), a phen
Publikováno v:
Radiology. 132:593-598
The radiographic appearance and clinical significance of gastric varices in the absence of esophageal varices and secondary to splenic vein occlusion were studied. Eighteen patients were evaluated through medical records, angiography, and barium stud
Publikováno v:
Southern Medical Journal. 78:173-177
Primary sclerosing cholangitis is a chronic, cholestatic disease affecting the biliary tree. Recent data suggest an autoimmune etiology. Clinical findings, roentgenographic characteristics, and compatible liver histology will help in establishing the
Publikováno v:
Gastroenterology. 81:1052-1060
Acetaminophen hepatotoxicity is believed to result from the metabolic conversion of acetaminophen to a highly reactive intermediate by cytochrome P 450. Cimetidine has been shown to be a potent inhibitor of cytochrome P 450-mediated drug metabolism i
Publikováno v:
Gastroenterology. 81(6)
Autor:
H A, Fuchs, G R, Avant
Publikováno v:
Journal of the Tennessee Medical Association. 77(10)
Publikováno v:
Gastroenterology. 82(1)
Cimetidine has been demonstrated to impair microsomal oxidative drug metabolism in a dose-dependent manner in an animal model. The inhibition has also been shown to be rapid, occurring after a single dose. In the present study we demonstrate that rec