Zobrazeno 1 - 10
of 24
pro vyhledávání: '"G. R. Avant"'
Publikováno v:
Southern Medical Journal. 78:173-177
Primary sclerosing cholangitis is a chronic, cholestatic disease affecting the biliary tree. Recent data suggest an autoimmune etiology. Clinical findings, roentgenographic characteristics, and compatible liver histology will help in establishing the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4558c7b4d595661d086031419d4fd121
https://doi.org/10.1097/00007611-198502000-00014
https://doi.org/10.1097/00007611-198502000-00014
Publikováno v:
Gastroenterology. 82:89-96
Cimetidine has been demonstrated to impair microsomal oxidative drug metabolism in a dose-dependent manner in an animal model. The inhibition has also been shown to be rapid, occurring after a single dose. In the present study we demonstrate that rec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f6f31a7e4b8b50cbbd7d736bbefd34e3
https://doi.org/10.1016/0016-5085(82)90128-7
https://doi.org/10.1016/0016-5085(82)90128-7
Publikováno v:
Radiology. 141:311-316
Oral cholecystography following the ingestion of 4.5 g of sodium tyropanoate (Bilopaque) was performed in 1,053 patients. The radiographs of 89 patients in whom the gallbladder was either faintly visualized or nonvisualized were reviewed for the pres
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c9b288eb285294a8bc8dcc8ca3b95288
https://doi.org/10.1148/radiology.141.2.7291552
https://doi.org/10.1148/radiology.141.2.7291552
Publikováno v:
Life Sciences. 24:1345-1350
Physostigmine (Antilirium R ) has been reported to reverse benzodiazepine- induced sleep or coma in man and prevent death in animals. Accordingly, we investigated the effect of Antilirium upon benzodiazepine binding to both rat and human brain. We re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::91106bf0ab16139a579739f7dc03130a
https://doi.org/10.1016/0024-3205(79)90003-1
https://doi.org/10.1016/0024-3205(79)90003-1
Autor:
Wade W Sutton, Robert H Bergstrand, Raymond L. Woosley, H T Wolfenden, Ted Wang, G. R. Avant, Dan M. Roden, Grant R. Wilkinson, Lyle A. Siddoway, Alastair J. J. Wood
Publikováno v:
Clinical Pharmacology and Therapeutics. 40:148-154
The antiarrhythmic agent encainide undergoes extensive first-pass hepatic metabolism after oral dosing. The active metabolites O-desmethylencainide and 3-methoxy-O-desmethylencainide are formed in subjects who are extensive metabolizers (EMs), a phen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::db34bcae12592a05e970c216558c717d
https://doi.org/10.1038/clpt.1986.155
https://doi.org/10.1038/clpt.1986.155
Publikováno v:
Radiology. 132:593-598
The radiographic appearance and clinical significance of gastric varices in the absence of esophageal varices and secondary to splenic vein occlusion were studied. Eighteen patients were evaluated through medical records, angiography, and barium stud
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::454dd57c6bac2725476e225b9f89544a
https://doi.org/10.1148/132.3.593
https://doi.org/10.1148/132.3.593
Publikováno v:
Gastroenterology. 81:1052-1060
Acetaminophen hepatotoxicity is believed to result from the metabolic conversion of acetaminophen to a highly reactive intermediate by cytochrome P 450. Cimetidine has been shown to be a potent inhibitor of cytochrome P 450-mediated drug metabolism i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9bed4f07083fb26a3bdae75366e76044
https://doi.org/10.1016/s0016-5085(81)80011-x
https://doi.org/10.1016/s0016-5085(81)80011-x
Publikováno v:
The American journal of gastroenterology. 81(1)
A 40-year-old man with a history of insulin-dependent diabetes mellitus was admitted to the hospital because of jaundice and pruritus. During his evaluation the diagnosis of primary sclerosing cholangitis and "microscopic" ulcerative colitis were est
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::7e6eba4a90f3b6ea2cfafe203d31995b
https://pubmed.ncbi.nlm.nih.gov/3942124
https://pubmed.ncbi.nlm.nih.gov/3942124
Publikováno v:
The American journal of digestive diseases. 20(3)
This study assessed the effect of alcoholic cirrhosis in man and of experimental liver injury in rats on the disposition and elimination of clindamycin. In 7 cirrhotics a statistically significant, although modest, prolongation of clindamycin half-li
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7528fa85dd0214a97ef4df527cb92374
https://pubmed.ncbi.nlm.nih.gov/1168411
https://pubmed.ncbi.nlm.nih.gov/1168411
Publikováno v:
The Journal of laboratory and clinical medicine. 97(1)
Antihistamines directed at either the H1 or H2 histamine receptor have the well-known side effect of sedation. The mechanism for the CNS depressant action of antihistamines is unknown. We examine here the possibility that the mechanism may involve mo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::8e2a573191e1d2614c2e137ad9b68b79
https://pubmed.ncbi.nlm.nih.gov/6108979
https://pubmed.ncbi.nlm.nih.gov/6108979