Zobrazeno 1 - 9 of 9 pro vyhledávání: '"G. R. Alaniz"'
1
Sustained elevated serum somatotropin concentrations in Holstein steers following subcutaneous delivery of a growth hormone releasing factor analog dispersed in water, oil or microspheres
Autor: W. M. Moseley, G. R. Alaniz, Cleary Dl, L. F. Krabill, J. F. Caputo, M.R Zantello, T.P Foster, M.W Leatherman, W. H. Claflin, J.R Wiest, X. Yu, D. R. Reeves
Publikováno v: Journal of Controlled Release. 47:91-99
Growth hormone releasing factor (GRF) stimulates pituitary somatotropin (ST) release. Somatotropin directly or indirectly through insulin like-growth factor I decreases lipogenesis and promotes protein accretion resulting in enhanced growth in food p
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::31ee7088a5cba3812c90bda69017aac4
https://doi.org/10.1016/s0168-3659(96)01623-9
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2
Position 2 and position 2/Ala15-substituted analogs of bovine growth hormone-releasing factor (bGRF) with enhanced metabolic stability and improved in vivo bioactivity
Autor: M. C. Goodwin, A. R. Friedman, R. M. Hillman, W. H. Claflin, A. K. Ichhpurani, G. R. Alaniz, Cleary Dl, Teresa M. Kubiak, C. R. Kelly, R. A. Martin
Publikováno v: Journal of Medicinal Chemistry. 36:888-897
In order to prepare GRF analogs with high activity in vivo, a strategy was undertaken to stabilize the peptide to dipeptidylpeptidase IV (DPP-IV), a protease found in plasma which inactivates native human and bovine GRF by cleavage of the Ala2-Asp3 b
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d5e2bf7b1bd52854f96e27a24774ff86
https://doi.org/10.1021/jm00059a014
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3
Recombinant bovine somatotropin improves growth performance in finishing beef steers1
Autor: M. C. Goodwin, G. R. Alaniz, W M Moseley, W. H. Claflin, J. B. Paulissen
Publikováno v: Journal of Animal Science. 70:412-425
The objectives of this study were to determine the efficacy of various doses of rbST on ADG and feed efficiency (FE) and to describe carcass composition changes in finishing beef steers. In Exp. 1, 96 crossbred beef steers (393 kg) received daily i.m
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::7b48a26a80dc4303308c83ee471ec521
https://doi.org/10.2527/1992.702412x
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4
Dose determination and confirmation of a long-acting formulation of ceftiofur (ceftiofur crystalline free acid) administered subcutaneously for the treatment of bovine respiratory disease
Autor: S. T. Chester, J. F. Boucher, K. J. Dame, B. Hibbard, G. R. Alaniz, E. J. Robb
Publikováno v: Journal of veterinary pharmacology and therapeutics. 25(3)
The objective of this work was to determine and confirm an effective dose of ceftiofur crystalline free acid sterile oil suspension (CCFA-SS, 100 mg ceftiofur equivalents (CE)/mL], a long-acting single-administration ceftiofur formulation, for the tr
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e33b20201cfd39e8dcba9a42b27b2026
https://pubmed.ncbi.nlm.nih.gov/12081612
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6
Growth hormone-releasing factor analogs with hydrophobic residues at position 19. Effects on growth hormone releasing activity in vitro and in vivo, stability in blood plasma in vitro, and secondary structure
Autor: W. H. Claflin, Prairie, Cleary Dl, T. R. Downs, Krueger Wc, L. A. Frohman, W. M. Moseley, A. R. Friedman, A. K. Ichhpurani, G. R. Alaniz
Publikováno v: Journal of medicinal chemistry. 35(21)
To test the hypothesis that replacing Ala19 in growth hormone-releasing factor (GRF) with more hydrophobic residues will increase growth hormone releasing activity, four GRF analogs were prepared and tested. The molecules were made by substituting Va
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e62ef2d1c303cd328ae84b10fe2ad7d9
https://pubmed.ncbi.nlm.nih.gov/1433201
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7
Recombinant bovine somatotropin improves growth performance in finishing beef steers
Autor: W M, Moseley, J B, Paulissen, M C, Goodwin, G R, Alaniz, W H, Claflin
Publikováno v: Journal of animal science. 70(2)
The objectives of this study were to determine the efficacy of various doses of rbST on ADG and feed efficiency (FE) and to describe carcass composition changes in finishing beef steers. In Exp. 1, 96 crossbred beef steers (393 kg) received daily i.m
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::a7fa73e22cf725f7eb4e76d4fca4b81c
https://pubmed.ncbi.nlm.nih.gov/1548203
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9
Food intake alters the serum growth hormone response to bovine growth hormone-releasing factor in meal-fed Holstein steers
Autor: L. F. Krabill, W. H. Claflin, G. R. Alaniz, W. M. Moseley
Publikováno v: The Journal of endocrinology. 117(2)
The hypothesis that endocrine or nutritional factors related to feeding may affect pituitary responsiveness to an acute challenge with bovine GH-releasing factor (1–44)-NH2 (GRF) was examined in steers. In these experiments, either steers were trai
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5759e664a9ae365e6a5f4954a97be5c3
https://pubmed.ncbi.nlm.nih.gov/3132525
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