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Akademický článek

Studies on the biosynthesis of cholesterol: XIV. the origin of prenoic acids from allyl Pyrophosphates in liver enzyme systems

Autor: J. Christophe, G. Popják

Publikováno v: Journal of Lipid Research, Vol 2, Iss 3, Pp 244-257 (1961)

Allyl pyrophosphates (3,3-dimethylallyl, geranyl, and farnesyl pyrophosphate), which are known intermediates in the biosynthesis of squalene from mevalonate, are also metabolized in the liver by an alternative pathway to acids. The first step in the

Externí odkaz: https://doaj.org/article/4930d6323dd0415f9a34a539aec3d637

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Akademický článek

Studies on the biosynthesis of cholesterol: XIII. phosphomevalonic kinase from liver

Autor: Hermione Hellig, G. Popják

Publikováno v: Journal of Lipid Research, Vol 2, Iss 3, Pp 235-243 (1961)

The enzyme, phosphomevalonic kinase, which catalyzes the formation of 5-pyrophosphomevalonate from 5-phosphomevalonate and ATP has been purified from pig liver. The reaction is reversible, the position of equilibrium lying on the side of the forward

Externí odkaz: https://doaj.org/article/c390ec92d3d0438a85d221870b083e20

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Akademický článek

Studies on the biosynthesis of cholesterol: XII. synthesis of allyl pyrophosphates from mevalonate and their conversion into squalene with liver enzymes

Autor: Dew.S. Goodman, G. Popják

Publikováno v: Journal of Lipid Research, Vol 1, Iss 4, Pp 286-300 (1960)

The biosynthesis of allyl pyrophosphates (the pyrophosphates of dimethylallyl alcohol, geraniol, and of farnesol) from dl-mevalonate-2-C14 and from (-)5-phosphomevalonate-2-C14 with soluble liver enzymes in the presence of ATP and Mg++ is described.

Externí odkaz: https://doaj.org/article/f044a7f721874b379213886aa3917404

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Akademický článek

Scintillation counter for the measurement of radioactivity of vapors in conjunction with gas-liquid chromatography

Autor: G. Popják, A.E. Lowe, D. Moore, L. Brown, F.A. Smith

Publikováno v: Journal of Lipid Research, Vol 1, Iss 1, Pp 29-39 (1959)

The construction and performance of a liquid scintillation counter for the measurement of radioactive vapors is described. The instrument is used in conjunction with a gas-liquid chromatographic instrument for the measurement of C14 contained in chro

Externí odkaz: https://doaj.org/article/c2dd7c68538543118dfef751acdcf4d9

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Akademický článek

Scintillation counter for simultaneous assay of H3 and C14 in gas-liquid chromatographic vapors

Autor: G. PopjáK, A.E. Lowe, D. Moore

Publikováno v: Journal of Lipid Research, Vol 3, Iss 3, Pp 364-371 (1962)

An instrument for the assay of H3 and of C14 in gas-liquid chromatographic effluents is described. The radioactive analysis is practically simultaneous with the mass-analysis. By the use of coincidence circuitry and pulse-height analysis with discrim

Externí odkaz: https://doaj.org/article/767c465b47384b71b6c2bfecc5e59539

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