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pro vyhledávání: '"G. Pointis"'
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Autor:
G. Pointis, M. A. Masini, C. Lanza, Felice Strollo, L. Scarabelli, Franco Ricci, S. Palmero, P. Prato
Publikováno v:
Advances in Space Research. 47:575-581
With the advent of space flights questions concerning the effects of microgravity (0×G) on human reproductive physiology have received great attention. The aim of this study was to evaluate the influence of 0×G on Sertoli cells. A Sertoli cell line
Autor:
J.M. Gasc, D. Segretain, J. Gilleron, G. Pointis, Norah Defamie, Diane Carette, V. Mauro, Daniel Chevallier
Publikováno v:
The Open Biomarkers Journal. 1:20-27
In the present study Cx43 mRNA and protein were analyzed in germ cells of men with normal spermatogenesis and in human testicular seminoma. In normal testis Cx43 mRNAs were basally located within seminiferous tubules and expressed in the most basally
Autor:
Marielle Nebout, S. Palmero, Dominique Segretain, Francoise Senegas-Balas, G. Pointis, Jérome Gilleron, L. Scarabelli
Publikováno v:
Journal of Cellular Physiology. 209:153-161
There is strong evidence that thyroid hormones through triiodothyronine (T3) regulate Sertoli cell proliferation and differentiation in the neonatal testis. However, the mechanism(s) by which they are able to control Sertoli cell proliferation is unc
Autor:
G. Pointis, Patrick Fénichel
Publikováno v:
Andrologie. 10:427-431
Plusieurs proteines detectees dans le liquide seminal ont ete proposees comme marqueur de la spermatogenese afin de mieux comprendre les mecanismes physiopathologiques de l’insuffisance spermatique et servir de facteur pronostic avant biopsie testi
Publikováno v:
Human Reproduction. 14:2020-2024
Anti-Mullerian hormone (AMH) also known as Mullerian inhibiting substance or factor, is a Sertoli cell-secreted glycoprotein responsible in male embryos for Mullerian duct regression. However, its role in adults remains unknown. AMH seminal concentra
Publikováno v:
Current molecular medicine. 13(8)
Direct intercellular communication is mediated by gap junctions and their constitutive proteins, the connexins, which are organized in a hexameric arrangement forming a channel between adjacent cells. Connexins are essential for cell homeostasis and
Publikováno v:
Molecular and Cellular Endocrinology. 99:25-30
The influence of spent medium from immature mouse Sertoli cells (SCM) on testosterone production by purified Leydig cells was investigated and compared to that of AVP, a potent local modulator of Leydig cell steroidogenesis. SCM inhibited in a dose-d
Autor:
V, Mauro, D, Carette, D, Chevallier, J F, Michiels, D, Segretain, G, Pointis, F, Sénégas-Balas
Publikováno v:
Histology and histopathology. 23(10)
Regenerating gene (Reg), encodes a secretory protein with growth and differentiation stimulating effects mostly in digestive tissues. Overexpression of Reg proteins and specifically of Reg I, one member of the Reg family, is associated with several h
Publikováno v:
Journal of cellular physiology. 200(1)
In the testis, spermatogenesis is a highly regulated process that includes germ cell multiplication and differentiation supported by Sertoli cells. Gap junction intercellular communication (GJIC), that is known to play an important role in the contro