Výsledky vyhledávání - "G. Plaetinck"

Knockdown of nuclease activity in the gut enhances RNAi efficiency in the Colorado potato beetle, Leptinotarsa decemlineata , but not in the desert locust, Schistocerca gregaria

Autor: Dulce Cordeiro dos Santos, Jornt Spit, G Plaetinck, Niels Wynant, A Philips, Jozef Vanden Broeck

Publikováno v: Insect Biochemistry and Molecular Biology. 81:103-116

The responsiveness towards orally delivered dsRNA and the potency of a subsequent environmental RNA interference (RNAi) response strongly differs between different insect species. While some species are very sensitive to dsRNA delivery through the di

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eca56a6ce13b8237bee3736f8b4dac8e
https://doi.org/10.1016/j.ibmb.2017.01.004

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Three residues in the common beta chain of the human GM-CSF, IL-3 and IL-5 receptors are essential for GM-CSF and IL-5 but not IL-3 high affinity binding and interact with Glu21 of GM-CSF

Autor: Christopher J. Bagley, G Plaetinck, Betty Zacharakis, Angel F. Lopez, S Qiyu, Joanna M. Woodcock, T R Hercus, J Tavernier

Publikováno v: The EMBO Journal. 13:5176-5185

The beta subunit (beta c) of the receptors for human granulocyte macrophage colony stimulating factor (GM-CSF), interleukin-3 (IL-3) and interleukin-5 (IL-5) is essential for high affinity ligand-binding and signal transduction. An important feature

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ffbf32265666cb5b576d9a6f78407401
https://doi.org/10.1002/j.1460-2075.1994.tb06848.x

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Control of IL-2 receptor-alpha expression by IL-1, tumor necrosis factor, and IL-2. Complex regulation via elements in the 5' flanking region

Autor: G Plaetinck, M C Combe, P Corthésy, P Sperisen, H Kanamori, T Honjo, M Nabholz

Publikováno v: The Journal of Immunology. 145:3340-3347

We have analyzed the mechanisms by which IL-1, IL-2, and TNF regulate expression of IL-2R alpha chain in a rodent T cell line. All three cytokines induce detectable IL-2R alpha mRNA by themselves, but there is strong synergy between IL-1 or TNF, on t

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::23075a5cbb62afb61492d6b1fa71656f
https://doi.org/10.4049/jimmunol.145.10.3340

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Structure/function analysis of human interleukin 5 and its receptor

Autor: J, Tavernier, S, Cornelis, R, Devos, Y, Guisez, G, Plaetinck, J, Van der Heyden

Publikováno v: Agents and actions. Supplements. 46

We have performed a detailed structure-function analysis of human interleukin 5 (hIL5) and its receptor. By testing a hIL5 mutant panel in a solid phase binding assay and a proliferation assay using hIL5 dependent cell-lines, areas on hIL5 involved i

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::7ffa208ca31e91e21c0fbf858338ebfa
https://pubmed.ncbi.nlm.nih.gov/7610988

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Characterization of the murine IL-5 receptor complex with the use of a panel of monoclonal antibodies. Relationship to the murine IL-3 receptor

Autor: J, Van der Heyden, R, Devos, G, Plaetinck, I, Fache, W, Fiers, J, Tavernier

Publikováno v: Journal of immunology (Baltimore, Md. : 1950). 147(10)

To obtain mAb against the murine IL-5R (mIL-5R), Wistar rats were immunized with B13 cells, a murine Ly-1+ (CD5+) pre-B cell line which is dependent on IL-3 or IL-5 for its growth. A first group of six mAb could immunoprecipitate, from detergent-lyse

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::4e12795faae64f07b6925f11cecf5e1b
https://pubmed.ncbi.nlm.nih.gov/1940345

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Interleukin 2 is both necessary and sufficient for the growth and differentiation of lectin-stimulated cytolytic T lymphocyte precursors

Autor: F Erard, P Corthesy, M Nabholz, J W Lowenthal, P Zaech, G Plaetinck, H R MacDonald

Publikováno v: The Journal of Immunology. 134:1644-1652

Minimal requirements for the growth and differentiation of lectin-stimulated cytolytic T lymphocyte precursors (CTL-P) have been investigated. CTL-P from murine spleen were purified by staining with monoclonal anti-Lyt-2 antibodies, followed by posit

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::e94891a9dc0c9ca60fc16e5783a6c9fc
https://doi.org/10.4049/jimmunol.134.3.1644

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Expression of the tumor necrosis factor locus is not necessary for the cytolytic activity of T lymphocytes

Autor: C V Jongeneel, S A Nedospasov, G Plaetinck, P Naquet, J C Cerottini

Publikováno v: The Journal of Immunology. 140:1916-1922

In order to test whether tumor necrosis factors alpha (TNF-alpha) or beta (TNF-beta, also known as lymphotoxin) are involved in the lysis of target cells by cytolytic T lymphocytes, we probed for the presence of the TNF mRNAs in several quiescent and

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::f1d8b08703d8dedcd70e0fde345ed160
https://doi.org/10.4049/jimmunol.140.6.1916

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cDNA cloning of granzyme C, a granule-associated serine protease of cytolytic T lymphocytes

Autor: D Jenne, C Rey, D Masson, K K Stanley, J Herz, G Plaetinck, J Tschopp

Publikováno v: The Journal of Immunology. 140:318-323

A cDNA clone corresponding to the complete amino acid sequence of a putative protease CCP2 of murine cytotoxic T lymphocytes was isolated and sequenced. The clone encodes a 248-residue long serine esterase. The deduced N-terminal amino acid sequence

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::e7499ddf48bf5e2bf0a9f0fe76d6c265
https://doi.org/10.4049/jimmunol.140.1.318

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