Zobrazeno 1 - 10
of 315
pro vyhledávání: '"G. Petur Nielsen"'
Autor:
Gaylor Boulay, Liliane C. Broye, Rui Dong, Sowmya Iyer, Rajendran Sanalkumar, Yu-Hang Xing, Rémi Buisson, Shruthi Rengarajan, Beverly Naigles, Benoît Duc, Angela Volorio, Mary E. Awad, Raffaele Renella, Ivan Chebib, G. Petur Nielsen, Edwin Choy, Gregory M. Cote, Lee Zou, Igor Letovanec, Ivan Stamenkovic, Miguel N. Rivera, Nicolò Riggi
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-17 (2024)
Abstract EWS fusion oncoproteins underlie several human malignancies including Desmoplastic Small Round Cell Tumor (DSRCT), an aggressive cancer driven by EWS-WT1 fusion proteins. Here we combine chromatin occupancy and 3D profiles to identify EWS-WT
Externí odkaz:
https://doaj.org/article/fd00253648764577aeb52739a580a6a3
Autor:
Emely Möller, Viviane Praz, Sanalkumar Rajendran, Rui Dong, Alexandra Cauderay, Yu-Hang Xing, Lukuo Lee, Carlo Fusco, Liliane C. Broye, Luisa Cironi, Sowmya Iyer, Shruthi Rengarajan, Mary E. Awad, Beverly Naigles, Igor Letovanec, Nicola Ormas, Giovanna Finzi, Stefano La Rosa, Fausto Sessa, Ivan Chebib, G. Petur Nielsen, Antonia Digklia, Dimitrios Spentzos, Gregory M. Cote, Edwin Choy, Martin Aryee, Ivan Stamenkovic, Gaylor Boulay, Miguel N. Rivera, Nicolò Riggi
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-18 (2022)
The relationship between cellular histogenesis and molecular phenotypes for the EWSR1- ATF1 fusion in clear cell sarcoma (CCS) requires further characterization. Here, the authors investigate the EWSR1-ATF1 gene regulation networks in CCS cell lines,
Externí odkaz:
https://doaj.org/article/1755fdc1556a4ae2aea83d025041fcd5
Autor:
Christopher E. Lietz, Erik T. Newman, Andrew D. Kelly, David H. Xiang, Ziying Zhang, Caroline A. Luscko, Santiago A. Lozano-Calderon, David H. Ebb, Kevin A. Raskin, Gregory M. Cote, Edwin Choy, G. Petur Nielsen, Benjamin Haibe-Kains, Martin J. Aryee, Dimitrios Spentzos
Publikováno v:
Communications Biology, Vol 5, Iss 1, Pp 1-20 (2022)
Christopher Lietz et al. examined genome-wide methylation in patient cohorts of primary osteosarcoma. Their results suggest that genomic hypomethylation is predictive of response to standard chemotherapy, and provide further insight into clinical imp
Externí odkaz:
https://doaj.org/article/90a95b6cbfc54bdc95e1e3c7e78c0b3f
Autor:
Sjoerd P. F. T. Nota, Ahmad Al-Sukaini, Shalin S. Patel, Francesco Sabbatino, G. Petur Nielsen, Vikram Deshpande, Jennifer H. Yearley, Soldano Ferrone, Xinhui Wang, Joseph H. Schwab
Publikováno v:
Frontiers in Oncology, Vol 11 (2021)
PurposeThe aim of this study was to characterize chondrosarcoma tumor infiltration by immune cells and the expression of immunologically relevant molecules. This information may contribute to our understanding of the role of immunological events in t
Externí odkaz:
https://doaj.org/article/51a12882044449668b7d1f66ff93ac3a
Autor:
Thomas F. DeLaney, MD, Yen-Lin Chen, MD, Elizabeth H. Baldini, MD MPH, Dian Wang, MD PhD, Judith Adams, CMD, Shea B. Hickey, BA, Beow Y. Yeap, ScD, Stephen M. Hahn, MD, Karen De Amorim Bernstein, MD, G. Petur Nielsen, MD, Edwin Choy, MD PhD, John T. Mullen, MD, Sam S. Yoon, MD
Publikováno v:
Advances in Radiation Oncology, Vol 2, Iss 1, Pp 85-93 (2017)
Purpose: To conduct phase 1 and 2 trials with photon intensity modulated radiation therapy and intensity modulated proton therapy (IMPT) arms to selectively escalate the retroperitoneal sarcoma preoperative radiation dose to tumor volume (clinical ta
Externí odkaz:
https://doaj.org/article/e94244dd1c6044ad976125c2071143db
Autor:
Alexa Burger, Aleksandr Vasilyev, Ritu Tomar, Martin K. Selig, G. Petur Nielsen, Randall T. Peterson, Iain A. Drummond, Daniel A. Haber
Publikováno v:
Disease Models & Mechanisms, Vol 7, Iss 7, Pp 907-913 (2014)
Chordoma is a malignant tumor thought to arise from remnants of the embryonic notochord, with its origin in the bones of the axial skeleton. Surgical resection is the standard treatment, usually in combination with radiation therapy, but neither chem
Externí odkaz:
https://doaj.org/article/7f6bf7432a9c451cb82eb23c13f9be21
Autor:
Josephine Kang, Maikel Botros, Saveli Goldberg, Christine Giraud, G. Petur Nielsen, Yen-Lin Chen, Kevin Raskin, Joseph Schwab, Sam S. Yoon, Francis J. Hornicek, Thomas F. DeLaney
Publikováno v:
Sarcoma, Vol 2013 (2013)
Background and Objectives. Atypical lipomas are uncommon, slow-growing benign tumors. While surgery has been the primary treatment modality, we have managed some patients with radiation (RT) as a component of the treatment and have reported their out
Externí odkaz:
https://doaj.org/article/974ce89d5b304830800d7886bd553a54
Publikováno v:
International Journal of Surgical Oncology, Vol 2011 (2011)
Synovial Sarcoma is a malignant mesenchymal tumor that comprises 5–10% of all soft tissue sarcomas. The mean age of onset is thirty years old. Intraosseous presentation is very rare and has only been documented a few times. We report herein a case
Externí odkaz:
https://doaj.org/article/fdd8daa1865948e09c6a815f8575c749
Autor:
Stefan C. Halvorsen, Yair Benita, Megan Hopton, Brooke Hoppe, Hilmar O. Gunnlaugsson, Parimal Korgaonkar, Charles R. Vanderburg, G. Petur Nielsen, Nicole Trepanowski, Jaime H. Cheah, Matthew P. Frosch, Joseph H. Schwab, Andrew E. Rosenberg, Francis J. Hornicek, Slim Sassi
Publikováno v:
The American Journal of Pathology. 193:532-547
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a798175f7a645df010844afa6d465fbd
https://doi.org/10.1016/j.ajpath.2023.01.014
https://doi.org/10.1016/j.ajpath.2023.01.014
Autor:
Myrsini Ioakeim-Ioannidou, Andrzej Niemierko, Daniel W Kim, Athena Tejada, Tobias Urell, Shannon Leahy, Judy Adams, Barbara Fullerton, G Petur Nielsen, Yin P Hung, Angela R Shih, Manuel Patino, Karen Buch, Sandra Rincon, Hilary Kelly, Mary Beth Cunnane, Maria Tolia, Brigitte C Widemann, Mary F Wedekind, Liny John, David Ebb, John H Shin, Gregory Cote, William Curry, Shannon M MacDonald
Publikováno v:
Neuro-Oncology.
Background Data on clinical outcomes for base of skull (BOS) chordomas in the pediatric population is limited. We report patient outcomes after surgery and proton radiotherapy (PRT). Methods Pediatric patients with BOS chordomas were treated with PRT
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a50a39e3cd8779a4c16a8755dc0eeec3
https://doi.org/10.1093/neuonc/noad068
https://doi.org/10.1093/neuonc/noad068