Zobrazeno 1 - 10
of 1 603
pro vyhledávání: '"G. Paterson"'
Publikováno v:
EJC Skin Cancer, Vol 2, Iss , Pp 100097- (2024)
Externí odkaz:
https://doaj.org/article/ac04502b170647b0935777c7e0ac3dcf
Emerging variants develop total escape from potent monoclonal antibodies induced by BA.4/5 infection
Autor:
Chang Liu, Raksha Das, Aiste Dijokaite-Guraliuc, Daming Zhou, Alexander J. Mentzer, Piyada Supasa, Muneeswaran Selvaraj, Helen M. E. Duyvesteyn, Thomas G. Ritter, Nigel Temperton, Paul Klenerman, Susanna J. Dunachie, Neil G. Paterson, Mark A. Williams, David R. Hall, Elizabeth E. Fry, Juthathip Mongkolsapaya, Jingshan Ren, David I. Stuart, Gavin R. Screaton
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-10 (2024)
Abstract The rapid evolution of SARS-CoV-2 is driven in part by a need to evade the antibody response in the face of high levels of immunity. Here, we isolate spike (S) binding monoclonal antibodies (mAbs) from vaccinees who suffered vaccine break-th
Externí odkaz:
https://doaj.org/article/cc28ab08066f4f34ade2b16555c78a91
Publikováno v:
PLoS ONE, Vol 19, Iss 4, p e0302008 (2024)
Malnutrition after stroke may lessen the beneficial effects of rehabilitation on motor recovery through influences on both brain and skeletal muscle. Enriched rehabilitation (ER), a combination of environmental enrichment and forelimb reaching practi
Externí odkaz:
https://doaj.org/article/605b263d8f5f4b8599f8c2ac955500c3
Autor:
Aiste Dijokaite-Guraliuc, Raksha Das, Daming Zhou, Helen M. Ginn, Chang Liu, Helen M.E. Duyvesteyn, Jiandong Huo, Rungtiwa Nutalai, Piyada Supasa, Muneeswaran Selvaraj, Thushan I. de Silva, Megan Plowright, Thomas A.H. Newman, Hailey Hornsby, Alexander J. Mentzer, Donal Skelly, Thomas G. Ritter, Nigel Temperton, Paul Klenerman, Eleanor Barnes, Susanna J. Dunachie, Cornelius Roemer, Thomas P. Peacock, Neil G. Paterson, Mark A. Williams, David R. Hall, Elizabeth E. Fry, Juthathip Mongkolsapaya, Jingshan Ren, David I. Stuart, Gavin R. Screaton, Christopher Conlon, Alexandra Deeks, John Frater, Siobhan Gardiner, Anni Jämsén, Katie Jeffery, Tom Malone, Eloise Phillips, Barbara Kronsteiner-Dobramysl, Priyanka Abraham, Sagida Bibi, Teresa Lambe, Stephanie Longet, Tom Tipton, Miles Carrol, Lizzie Stafford
Publikováno v:
Cell Reports, Vol 42, Iss 4, Pp 112271- (2023)
Summary: In November 2021, Omicron BA.1, containing a raft of new spike mutations, emerged and quickly spread globally. Intense selection pressure to escape the antibody response produced by vaccines or severe acute respiratory syndrome coronavirus 2
Externí odkaz:
https://doaj.org/article/74b091e4af5241cd9320ea266b208fa6
Autor:
Tamar Skaist Mehlman, Justin T Biel, Syeda Maryam Azeem, Elliot R Nelson, Sakib Hossain, Louise Dunnett, Neil G Paterson, Alice Douangamath, Romain Talon, Danny Axford, Helen Orins, Frank von Delft, Daniel A Keedy
Publikováno v:
eLife, Vol 12 (2023)
Much of our current understanding of how small-molecule ligands interact with proteins stems from X-ray crystal structures determined at cryogenic (cryo) temperature. For proteins alone, room-temperature (RT) crystallography can reveal previously hid
Externí odkaz:
https://doaj.org/article/aac320db06f049d18577b3ebd803e700
Autor:
Sarah J. Lehnert, Shauna M. Baillie, John MacMillan, Ian G. Paterson, Colin F. Buhariwalla, Ian R. Bradbury, Paul Bentzen
Publikováno v:
Evolutionary Applications, Vol 13, Iss 5, Pp 1069-1089 (2020)
Abstract Many populations of freshwater fishes are threatened with losses, and increasingly, the release of hatchery individuals is one strategy being implemented to support wild populations. However, stocking of hatchery individuals may pose long‐
Externí odkaz:
https://doaj.org/article/885f50081fae4b868e4dd2d95d42ae57
Autor:
Kara K. S. Layton, Brian Dempson, Paul V. R. Snelgrove, Steven J. Duffy, Amber M. Messmer, Ian G. Paterson, Nicholas W. Jeffery, Tony Kess, John B. Horne, Sarah J. Salisbury, Daniel E. Ruzzante, Paul Bentzen, David Côté, Cameron M. Nugent, Moira M. Ferguson, Jong S. Leong, Ben F. Koop, Ian R. Bradbury
Publikováno v:
Evolutionary Applications, Vol 13, Iss 5, Pp 1055-1068 (2020)
Abstract The resiliency of populations and species to environmental change is dependent on the maintenance of genetic diversity, and as such, quantifying diversity is central to combating ongoing widespread reductions in biodiversity. With the advent
Externí odkaz:
https://doaj.org/article/8a3048d1814a4ba995fc8819d0f68782
Autor:
Helena A. Turton, Josephine Pickworth, Gordon G. Paterson, Allan Lawrie, J. Kenneth Baillie, A. A. Roger Thompson
Publikováno v:
Frontiers in Physiology, Vol 13 (2022)
Reduced oxygen tensions experienced at high altitudes are thought to predispose to thrombosis, yet there are few studies linking hypoxia, platelet activation, and thrombosis. Reports of platelet phenotypes in hypoxia are inconsistent, perhaps due to
Externí odkaz:
https://doaj.org/article/f52a4978171c4d938440098228ff79c9
Publikováno v:
Ecology and Evolution, Vol 9, Iss 23, Pp 13567-13584 (2019)
Abstract Interpretation of conservation status should be informed by an appreciation of genetic diversity, past demography, and overall trends in population size, which contribute to a species' evolutionary potential and resilience to genetic risks.
Externí odkaz:
https://doaj.org/article/0f3b6492eb1b4fe4bfe9492b4581c6be
Publikováno v:
IACR Transactions on Symmetric Cryptology, Pp 277-313 (2018)
Statistical analysis of ciphertexts has been recently used to carry out devastating inference attacks on deterministic encryption (Naveed, Kamara, and Wright, CCS 2015), order-preserving/revealing encryption (Grubbs et al., S&P 2017), and searchable
Externí odkaz:
https://doaj.org/article/4ceb50061e52427594dec0f338619602