Zobrazeno 1 - 10
of 803
pro vyhledávání: '"G. PATTON"'
Autor:
Hannah Nelson, Sherman Qu, Jeffrey L. Franklin, Qi Liu, Heather H. Pua, Kasey C. Vickers, Alissa M. Weaver, Robert J. Coffey, James G. Patton
Publikováno v:
RNA Biology, Vol 21, Iss 1, Pp 805-819 (2024)
Extracellular vesicles and nanoparticles (EVPs) are now recognized as a novel form of cell–cell communication. All cells release a wide array of heterogeneous EVPs with distinct protein, lipid, and RNA content, dependent on the pathophysiological s
Externí odkaz:
https://doaj.org/article/0149ce03e8b64eb8b051c0b241d31077
5‐Fluorouracil treatment represses pseudouridine‐containing miRNA export into extracellular vesicles
Autor:
Shimian Qu, Hannah M. Nelson, Xiao Liu, Yu Wang, Elizabeth M. Semler, Danielle L. Michell, Clark Massick, Jeffrey L. Franklin, John Karijolich, Alissa M. Weaver, Robert J. Coffey, Qi Liu, Kasey C. Vickers, James G. Patton
Publikováno v:
Journal of Extracellular Biology, Vol 3, Iss 9, Pp n/a-n/a (2024)
Abstract 5‐Fluorouracil (5‐FU) has been used for chemotherapy for colorectal and other cancers for over 50 years. The prevailing view of its mechanism of action is inhibition of thymidine synthase leading to defects in DNA replication and repair.
Externí odkaz:
https://doaj.org/article/6e5702c671f04d8e9a2013298d18c044
Autor:
Arthur Casulli de Oliveira, Luiz Augusto Bovolenta, Lucas Figueiredo, Amanda De Oliveira Ribeiro, Beatriz Jacinto Alves Pereira, Talita Roberto Aleixo de Almeida, Vinicius Farias Campos, James G Patton, Danillo Pinhal
Publikováno v:
Evolutionary Bioinformatics, Vol 20 (2024)
In metazoans, microRNAs (miRNAs) are essential regulators of gene expression, affecting critical cellular processes from differentiation and proliferation, to homeostasis. During miRNA biogenesis, the miRNA strand that loads onto the RNA-induced Sile
Externí odkaz:
https://doaj.org/article/f4fb1990d2bb499384b2064da442af49
Publikováno v:
Geophysical Research Letters, Vol 50, Iss 7, Pp n/a-n/a (2023)
Abstract Oxidation of reactive carbon fuels climate‐ and pollution‐relevant chemistry. Deciduous forests are important sources of reactive carbon (particularly isoprene). Organization in turbulence can physically separate (“segregate”) oxidan
Externí odkaz:
https://doaj.org/article/f08297e6ec0248668d5d39b3a9183b6b
Autor:
Hao Liu, Danxiu Li, Lina Sun, Hongqiang Qin, Ahui Fan, Lingnan Meng, Ramona Graves-Deal, Sarah E. Glass, Jeffrey L. Franklin, Qi Liu, Jing Wang, Timothy J. Yeatman, Hao Guo, Hong Zong, Shuilin Jin, Zhiyu Chen, Ting Deng, Ying Fang, Cunxi Li, John Karijolich, James G. Patton, Xin Wang, Yongzhan Nie, Daiming Fan, Robert J. Coffey, Xiaodi Zhao, Yuanyuan Lu
Publikováno v:
Molecular Cancer, Vol 21, Iss 1, Pp 1-18 (2022)
Abstract Background Epithelial-to-mesenchymal transition (EMT) is a process linked to metastasis and drug resistance with non-coding RNAs (ncRNAs) playing pivotal roles. We previously showed that miR-100 and miR-125b, embedded within the third intron
Externí odkaz:
https://doaj.org/article/2ff435c04f444160b7d52b6cb613bda6
Autor:
X. Pedruzo‐Bagazgoitia, E. G. Patton, A. F. Moene, H. G. Ouwersloot, T. Gerken, L. A. T. Machado, S. T. Martin, M. Sörgel, P. C. Stoy, M. A. Yamasoe, J. Vilà‐Guerau de Arellano
Publikováno v:
Journal of Advances in Modeling Earth Systems, Vol 15, Iss 2, Pp n/a-n/a (2023)
Abstract We investigate the atmospheric diurnal variability inside and above the Amazonian rainforest for a representative day during the dry season. To this end, we combine high‐resolution large‐eddy simulations that are constrained and evaluate
Externí odkaz:
https://doaj.org/article/880e7ef200ba46b1844464e84893bf1c
Publikováno v:
Atmosphere, Vol 14, Iss 7, p 1107 (2023)
Recent high-resolution large-eddy simulations (LES) of a stable atmospheric boundary layer (SBL) with mesh sizes N=(5123,10243,20483) or mesh spacings ▵=(0.78,0.39,0.2) m are analyzed. The LES solutions are judged to be converged based on the good
Externí odkaz:
https://doaj.org/article/71cc8b5379ca43d9ab46b237898659ab
Publikováno v:
Atmosphere, Vol 14, Iss 7, p 1136 (2023)
Atmospheric turbulence, which produces chaotic motions in the planetary boundary layer, can inhibit mixing between fast-reacting species produced or released at different locations. This segregation process modifies the effective rate at which reacti
Externí odkaz:
https://doaj.org/article/3963130325f347f6b1a3d4c2e213cfec
Autor:
Thomas Yetter, MS, Andrew G. Patton, MD, Ahmed Mansi, MD, Nicholas Maassen, MD, Jeremy S. Somerson, MD
Publikováno v:
JSES International, Vol 5, Iss 3, Pp 597-600 (2021)
Background: Most patients have successful outcomes with minimal limitations after distal biceps repair, but a minority continues experiencing functional constraints. We hypothesize that low scores on a validated mental health measure correlate with w
Externí odkaz:
https://doaj.org/article/16a1071e9409476d8853ae06b73e1503
Autor:
Pedro G. Nachtigall, Luiz A. Bovolenta, James G. Patton, Bastian Fromm, Ney Lemke, Danillo Pinhal
Publikováno v:
BMC Genomics, Vol 22, Iss 1, Pp 1-20 (2021)
Abstract Background During vertebrate evolution, the heart has undergone remarkable changes that lead to morphophysiological differences in the fully formed heart of these species, such as chamber septation, heart rate frequency, blood pressure, and
Externí odkaz:
https://doaj.org/article/c20ad12303eb40508da0777f6ac6ca00