A seminal study on the mechanisms underlying spontaneous activity of the seminal vesicles?

Autor: M A, Hollywood, K D, Thornbury, G P, Sergeant

The mucosa may have neuron‐like functions as urinary bladder mucosa releases bioactive substances that modulate sensory nerve activity as well as detrusor muscle contractility. However, such mucosal function in other visceral organs remains to be e

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::b241207189a9e31d7a0fca7fb09be62d
https://europepmc.org/articles/PMC5509879/

Royal Academy of Medicine in Ireland Section of Biomedical Sciences

Autor: C. G. Gallagher, J. G. Noble, L. A. J. O’Neill, G. Boland, M. Quinn, M. A. Hollywood, I. D. Hill, C. Sweeney, C. M. O’Connor, B. F. Leek, M. D. Walker, R. G. O’Regan, D. C. Moriarty, A. J. Mackarel, S. O’Connor, K. M. O’Boyle, A. Moore, B. A. Gormley, A. McGuigan, J. J. O’Connor, P. McLoughlin, G. Saleshando, T. Robson, F. M. Keane, N. G. McHale, C. S. Downes, C. E. Herron, C. R. Barnett, H. R. Harty, S. R. McKeown, S. Ryan, S. M. McDonough, A. E. Dusoir, C. N. Scholfield, G. O’Cuinn, E. O’Loinsigh, E. M. Dunne, D. M. Cannon, M. McGuire, K. M. Lagan, S. D. Moore, D. M. Walsh, A. F. L. Cramp, W. T. McNicholas, A. S. Lowe, P. P. Corkery, K. D. McCloskey, J. M. Allen, P. D. Glasgow, D. Cox, C. Hutchinson, D. G. Hirst, T. Quinn, P. Nolan, E. Kilbride, G. McBean, A. K. Keenan, T. M. Curtis, V. C. Cullen, D. A. Hurley, S. Wilson, C. R. Clarke, G. D. Baxter, D. Hirst, H. P. Frizelle, A. Bradford, J. P. Ryan, B. P. Curran, S. W. Kerrigan, A. W. Baird, B. M. Hannigan, O. Carroll, D. J. Fitzerald, K. D. Thornbury, P. J. Magee, G. P. Sergeant, R. Humphrey

Publikováno v: Irish Journal of Medical Science. 168:286-297

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::f611db24e64866b1046267ac4433f69a
https://doi.org/10.1007/bf02944360

Pharmacological and molecular evidence for the involvement of Kv4.3 in ultra-fast activating K+ currents in murine portal vein myocytes

Autor: S Y M, Yeung, S, Ohya, G P, Sergeant, V, Pucovský, I A, Greenwood

Publikováno v: British journal of pharmacology. 149(6)

The aim of this study was to determine the molecular identity of a transient K+ current (termed IUF) in mouse portal vein myocytes using pharmacological and molecular tools.Whole cell currents were recorded using the ruptured patch con from either ac

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::e0df5696fec2d192d894ab679a2b66f9
https://pubmed.ncbi.nlm.nih.gov/17016508

Activation of the cGMP/PKG pathway inhibits electrical activity in rabbit urethral interstitial cells of Cajal by reducing the spatial spread of Ca2+ waves

Autor: G P, Sergeant, Louise, Johnston, N G, McHale, K D, Thornbury, M A, Hollywood

Publikováno v: The Journal of physiology. 574(Pt 1)

In the present study we used a combination of patch clamping and fast confocal Ca2+ imaging to examine the effects of activators of the nitric oxide (NO)/cGMP pathway on pacemaker activity in freshly dispersed ICC from the rabbit urethra, using the a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::3854353e23bccbcfb5aaecb3740e5778
https://pubmed.ncbi.nlm.nih.gov/16644801

Modulation of spontaneous Ca2+-activated Cl- currents in the rabbit corpus cavernosum by the nitric oxide-cGMP pathway

Autor: M, Craven, G P, Sergeant, M A, Hollywood, N G, McHale, K D, Thornbury

Publikováno v: The Journal of physiology. 556(Pt 2)

The whole-cell perforated patch clamp technique was used to study membrane currents in isolated rabbit corpus cavernosum smooth muscle cells. Depolarization from -80 mV to the range -40 to -10 mV evoked a nifedipine-sensitive Ca(2+) current that was

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::476a08323e8a309fffe1a2db2b283bbe
https://pubmed.ncbi.nlm.nih.gov/14766939