Zobrazeno 1 - 5
of 5
pro vyhledávání: '"G. P. Poole"'
Publikováno v:
Hormone and Metabolic Research. 14:536-539
This work was undertaken to examine the relationship between the binding, internalisation and degradation of insulin by isolated rat hepatocytes. Internalisation of hormone reached a maximum after 5-7 minutes at 37 degrees C; at an insulin concentrat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b53e8901b124ac21a4bde6d7659a6a1a
https://doi.org/10.1055/s-2007-1019070
https://doi.org/10.1055/s-2007-1019070
Publikováno v:
The Biochemical journal. 180(3)
1. Evidence is presented that exposure of epididymal fat-pads from fed rats to insulin leads to a marked diminution in the Km for phosphoenolpyruvate of pyruvate kinase. Effects of insulin may be readily demonstrated in experiments both in vivo and i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7c61b7ab9054c9d927c675e7aac32659
https://pubmed.ncbi.nlm.nih.gov/486131
https://pubmed.ncbi.nlm.nih.gov/486131
Publikováno v:
Diabetologia. 23
Isolated rat hepatocytes degraded 125I-insulin with a Km of 150 nmol/l. Degradation was stimulated by the addition of glutathione and dithiothreitol. In cells incubated with diamide, glutathione was oxidised to the disulphide. Regeneration of reduced
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9afc8ace5cf28c37635579aa9b37ac5a
https://doi.org/10.1007/bf00257731
https://doi.org/10.1007/bf00257731
Publikováno v:
Biochemical Society transactions. 8(3)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::a6c845c69870087a6df7f9cd26754611
https://pubmed.ncbi.nlm.nih.gov/6995203
https://pubmed.ncbi.nlm.nih.gov/6995203
Publikováno v:
Bioscience reports. 1(12)
The metabolism of 125I-labelled insulin by hepatocytes isolated from 48-h-starved Zucker lean and obese rats was studied. Hepatocytes from the lean animals bound significantly more 125I-labelled insulin and had a greater receptor number per cell than
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d588eb2c24927a0c41a2794415c8bff8
https://pubmed.ncbi.nlm.nih.gov/7032619
https://pubmed.ncbi.nlm.nih.gov/7032619