Zobrazeno 1 - 10
of 506
pro vyhledávání: '"G. P. MURPHY"'
Autor:
Teresa Del Bianco, Meng-Chuan Lai, Luke Mason, Mark H. Johnson, Tony Charman, Eva Loth, Tobias Banaschewski, Jan Buitelaar, Declan G. M. Murphy, Emily J. H. Jones, The AIMS-2-TRIALS LEAP Team
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-15 (2024)
Abstract Face-processing timing differences may underlie visual social attention differences between autistic and non-autistic people, and males and females. This study investigates the timing of the effects of neurotype and sex on face-processing, a
Externí odkaz:
https://doaj.org/article/701e5ce6e44049398e0000b900cd20ba
Autor:
Tobias P. Whelan, Eileen Daly, Nicolaas A. Puts, Paula Smith, Carrie Allison, Simon Baron-Cohen, Ekaterina Malievskaia, Declan G. M. Murphy, Grainne M. McAlonan
Publikováno v:
BMC Psychiatry, Vol 24, Iss 1, Pp 1-11 (2024)
Abstract Background The underlying neurobiology of the complex autism phenotype remains obscure, although accumulating evidence implicates the serotonin system and especially the 5HT2A receptor. However, previous research has largely relied upon asso
Externí odkaz:
https://doaj.org/article/cfecf35bb67a407984c82a33eb4ceb24
Autor:
Louise Gallagher, Michael Absoud, Miguel Castelo-Branco, Tony Charman, Maja Hempel, Richard Delorme, Guiomar Oliveira, Roberta Battini, Sven Bölte, Claire S Leblond, Thomas Bourgeron, Alexandra Lautarescu, Mercedes Serrano, Federico Vigevano, Christian P Schaaf, Bethany Oakley, Julian Tillmann, Pierre Violland, Declan G M Murphy, Sarah Douglas, Paolo Bonanni, Grainne McAlonan, Roberta Milone, Josefina Castro-Fornieles, Madeleine Bloomfield, Síofra Heraty, Roderik Plas, Anjuli Ghosh, Katrien Van den Bosch, Eliza Eaton, Ana Blázquez Hinojosa, Nadia Bolshakova, Jacqueline Borg, Sara Calderoni, Rosa Calvo Escalona, Pilar Caro, Freddy Cliquet, Alberto Danieli, Maurizio Elia, Nuno Madeira, Ciara J Molloy, Susana Mouga, Virginia Montiel, Ana Pina Rodrigues, Kristiina Tammimies, Charlotte Tye, Beatrice Mazzone, Cara O’Neill, Julie Pender, Verena Romero, Christopher Chatham
Publikováno v:
BMJ Open, Vol 14, Iss 6 (2024)
Introduction Autism is a common neurodevelopmental condition with a complex genetic aetiology that includes contributions from monogenic and polygenic factors. Many autistic people have unmet healthcare needs that could be served by genomics-informed
Externí odkaz:
https://doaj.org/article/815fdc95324e48c4ab0f1f29dd80968c
Autor:
Suzanne O’ Brien, Arjun Sethi, James Blair, Essi Viding, Ahmad Beyh, Mitul A. Mehta, Robert Dallyn, Christine Ecker, Marija M. Petrinovic, Moira Doolan, Nigel Blackwood, Marco Catani, Declan G. M. Murphy, Stephen Scott, Michael C. Craig
Publikováno v:
Translational Psychiatry, Vol 13, Iss 1, Pp 1-9 (2023)
Abstract Studies report that the microstructural integrity of the uncinate fasciculus (UF; connecting the anterior temporal lobe to the orbitofrontal cortex) is abnormal in adults with psychopathy and children with conduct problems (CP), especially t
Externí odkaz:
https://doaj.org/article/324b93ba6c1b43aca26422414b40b95d
Autor:
Qiyun Huang, Hester Velthuis, Andreia C. Pereira, Jumana Ahmad, Samuel F. Cooke, Claire L. Ellis, Francesca M. Ponteduro, Nicolaas A. J. Puts, Mihail Dimitrov, Dafnis Batalle, Nichol M. L. Wong, Lukasz Kowalewski, Glynis Ivin, Eileen Daly, Declan G. M. Murphy, Gráinne M. McAlonan
Publikováno v:
Translational Psychiatry, Vol 13, Iss 1, Pp 1-13 (2023)
Abstract Altered reactivity and responses to auditory input are core to the diagnosis of autism spectrum disorder (ASD). Preclinical models implicate ϒ-aminobutyric acid (GABA) in this process. However, the link between GABA and auditory processing
Externí odkaz:
https://doaj.org/article/080c60be586548ea8e74626428104029
Autor:
Lennart M. Oblong, Alberto Llera, Ting Mei, Koen Haak, Christina Isakoglou, Dorothea L. Floris, Sarah Durston, Carolin Moessnang, Tobias Banaschewski, Simon Baron-Cohen, Eva Loth, Flavio Dell’Acqua, Tony Charman, Declan G. M. Murphy, Christine Ecker, Jan K. Buitelaar, Christian F. Beckmann, The EU-AIMS LEAP Group, Natalie J. Forde
Publikováno v:
Molecular Autism, Vol 14, Iss 1, Pp 1-13 (2023)
Abstract Neuroimaging analyses of brain structure and function in autism have typically been conducted in isolation, missing the sensitivity gains of linking data across modalities. Here we focus on the integration of structural and functional organi
Externí odkaz:
https://doaj.org/article/21bc23d9ff2f4d92a9346b2ff7431cce
Autor:
Christina Isakoglou, Koen V. Haak, Thomas Wolfers, Dorothea L. Floris, Alberto Llera, Marianne Oldehinkel, Natalie J. Forde, Bethany F. M. Oakley, Julian Tillmann, Rosemary J. Holt, Carolin Moessnang, Eva Loth, Thomas Bourgeron, Simon Baron-Cohen, Tony Charman, Tobias Banaschewski, Declan G. M. Murphy, Jan K. Buitelaar, Andre F. Marquand, Christian F. Beckmann
Publikováno v:
Translational Psychiatry, Vol 13, Iss 1, Pp 1-10 (2023)
Abstract Sensory atypicalities are particularly common in autism spectrum disorders (ASD). Nevertheless, our knowledge about the divergent functioning of the underlying somatosensory region and its association with ASD phenotype features is limited.
Externí odkaz:
https://doaj.org/article/712369da7c32477cafd4d8813f36bb21
Autor:
Andreia C Pereira, Alison Leonard, Hester Velthuis, Nichol M L Wong, Francesca M Ponteduro, Mihail Dimitrov, Claire L Ellis, Lukasz Kowalewski, David J Lythgoe, Diana-Georgina Rotaru, Richard A E Edden, Glynis Ivin, Charlotte M Pretzsch, Eileen Daly, Declan G M Murphy, Gráinne M McAlonan
Publikováno v:
PLoS ONE, Vol 19, Iss 8, p e0308792 (2024)
BackgroundThe neurobiological underpinnings of Autism Spectrum Disorder (ASD) are diverse and likely multifactorial. One possible mechanism is increased oxidative stress leading to altered neurodevelopment and brain function. However, this hypothesis
Externí odkaz:
https://doaj.org/article/1891eaae2ef6411896f44b4b225e28f9
Autor:
Nico Bast, Luke Mason, Christine Ecker, Sarah Baumeister, Tobias Banaschewski, Emily J. H. Jones, Declan G. M. Murphy, Jan K. Buitelaar, Eva Loth, Gahan Pandina, the EU-AIMS LEAP Group, Christine M. Freitag
Publikováno v:
Molecular Autism, Vol 14, Iss 1, Pp 1-16 (2023)
Abstract Background Attenuated social attention is a key marker of autism spectrum disorder (ASD). Recent neuroimaging findings also emphasize an altered processing of sensory salience in ASD. The locus coeruleus–norepinephrine system (LC-NE) has b
Externí odkaz:
https://doaj.org/article/f0ff1acb53c2448d9a3f3ce7502f0330
Autor:
Viola Hollestein, Geert Poelmans, Natalie J. Forde, Christian F. Beckmann, Christine Ecker, Caroline Mann, Tim Schäfer, Carolin Moessnang, Sarah Baumeister, Tobias Banaschewski, Thomas Bourgeron, Eva Loth, Flavio Dell’Acqua, Declan G. M. Murphy, Nicolaas A. Puts, Julian Tillmann, Tony Charman, Emily J. H. Jones, Luke Mason, Sara Ambrosino, Rosemary Holt, Sven Bölte, Jan K. Buitelaar, Jilly Naaijen
Publikováno v:
Translational Psychiatry, Vol 13, Iss 1, Pp 1-9 (2023)
Abstract The excitatory/inhibitory (E/I) imbalance hypothesis posits that imbalance between excitatory (glutamatergic) and inhibitory (GABAergic) mechanisms underlies the behavioral characteristics of autism. However, how E/I imbalance arises and how
Externí odkaz:
https://doaj.org/article/e83023aeeeab4df09a5c4172ff9204e6