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Akademický článek
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Publikováno v:
Drug discovery today. 22(3)
Tuberculosis (TB) drug discovery research is hampered by several factors, but as in many research areas, the available funding is insufficient to support the needs of research and development. Recent years have seen various large collaborative effort
Akademický článek
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Publikováno v:
Research in Microbiology. 149:235-245
A DNA library of strain HB19 from Borrelia burgdorferi sensu stricto, an agent of Lyme borreliosis, was constructed in the cosmid pLA2917. Genes involved in initiation of DNA replication and resolution of recombination intermediates (Holliday junctio
Publikováno v:
Microbiology. 143:1681-1690
A cluster of flagellar genes of Borrelia burgdorferi was identified and sequenced. This cluster comprises an operon, designated the flgK operon, which is initiated by a s70-like promoter. The flgK operon consists of flbF (function unknown), flgK (enc
Publikováno v:
Microbiology. 140:1803-1816
Autor:
S. Strathdee, K. Phillips, O. Navratil, John B. Rafferty, Iain W. Manfield, Peter G. Stockley, Simon E. V. Phillips, Isabelle Saint-Girons, William S. Somers, Iain G. Old, Teresa McNally, Yi-Yuan He
Publikováno v:
Annals of the New York Academy of Sciences. 726:105-117
The crystal structure of the E. coli met repressor in complex with a synthetic 19-base pair oligonucleotide reveals two dimeric repressor molecules bound to adjacent sites on the DNA. The oligonucleotide contains two adjacent repeats of an 8-mer know
Autor:
K.-E. Ehwald, St. Marschmeyer, Mario Birkholz, St. Döbereiner, P. Kulse, H.-J. Bruck, G. Scheuring, G. Old, Joachim Bauer, F. Hillmann, Ulrich Haak, K. Schulz, Mehmet Kaynak
Publikováno v:
27th European Mask and Lithography Conference.
This paper presents a backside-to-frontside alignment technique for the backside processing of Si wafers. Integrated MEMS components like BiCMOS-embedded RF-MEMS switches require accurate (1-2μm) alignment. We demonstrate an alignment technique prov
Autor:
Giulia C. Kennedy, Ana Maria Burguiere, Walter Lee, Hervé Bourhy, Philip Dickinson, Gilberte Coralie, Laurent Dacheux, Nicolas Berthet, Christopher Davies, Stewart T. Cole, Christophe Batéjat, Anita K. Reinhardt, Ingrid Filliol, Tatiana Vallaeys, Iain G. Old, Yaron Turpaz, Beate Heym, Shenglan Zhang, Katherine A. Kong, Jean Claude Manuguerra
Publikováno v:
Microbial Biotechnology
Microbial Biotechnology, 2008, 1 (1), pp.79-86. ⟨10.1111/j.1751-7915.2007.00012.x⟩
Microbial Biotechnology, Wiley, 2008, 1 (1), pp.79-86. ⟨10.1111/j.1751-7915.2007.00012.x⟩
Microbial Biotechnology, 2008, 1 (1), pp.79-86. ⟨10.1111/j.1751-7915.2007.00012.x⟩
Microbial Biotechnology, Wiley, 2008, 1 (1), pp.79-86. ⟨10.1111/j.1751-7915.2007.00012.x⟩
International audience; Identification of microbial pathogens in clinical specimens is still performed by phenotypic methods that are often slow and cumbersome, despite the availability of more comprehensive genotyping technologies. We present an app
Publikováno v:
FEMS Microbiology Letters. 111:109-114
The complete nucleotide sequence of the Borrelia burgdorferi dnaA gene (encoding the initiator protein of chromosome replication) and its flanking regions was determined. The putative DnaA polypeptide exhibited 29-42% identity with those of other eub