Zobrazeno 1 - 10
of 656
pro vyhledávání: '"G. Obe"'
Autor:
G. Obe, Christian Johannes
Publikováno v:
Methods in Molecular Biology ISBN: 9781493996452
Methods in Molecular Biology ISBN: 9781627035286
Methods in Molecular Biology ISBN: 9781627035286
Human peripheral lymphocytes (HPL) are non-cycling primary cells (G0 cells). They are easily collectable by venipuncture. In the presence of suitable culture media and stimulants in vitro HPL enter the cell cycle and divide mitotically. Metaphase-lik
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::01ef24e8764e007f769bf24859d709c4
https://doi.org/10.1007/978-1-4939-9646-9_6
https://doi.org/10.1007/978-1-4939-9646-9_6
Publikováno v:
Radiation Research. 161:540-548
Genomic fingerprints of mutagenic agents would have wide applications in the field of cancer biology, epidemiology and prevention. The differential spectra of chromosomal aberrations induced by different clastogens suggest that ratios of specific abe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dc39de416d0a24bfef1ed4adcdfb532c
https://doi.org/10.1667/rr3157
https://doi.org/10.1667/rr3157
Autor:
David J. Chen, Marco Durante, G. Obe, S. Conrad, D C van Gent, Adayapalam T. Natarajan, Joel S. Bedford, Michael N. Cornforth
Publikováno v:
Mutation Research. Genetic Toxicology and Environmental Mutagenesis, 756(1-2), 5-13. Elsevier
Despite many years of experimental studies on radiation-induced chromosomal aberrations, and the recent progress in elucidating the molecular mechanisms of the DNA damage response, the link between DNA double-strand break repair and its expression as
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::73550aa68f5ac6f6836a836cd98c53cf
https://doi.org/10.1016/j.mrgentox.2013.05.014
https://doi.org/10.1016/j.mrgentox.2013.05.014
Publikováno v:
International Journal of Radiation Biology. 80:437-443
To measure the location of heavy ion-induced residual breakpoints in human chromosome 5 and the size distribution of chromosome fragments involved in inter- or intrachromosomal exchanges.Human peripheral blood lymphocytes were exposed to 4 Gy acceler
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::204f1ffdcdea4b4b90a8d72bfba29bd4
https://doi.org/10.1080/09553000410001702337
https://doi.org/10.1080/09553000410001702337
Autor:
M.V. Di-Tomaso, Wilner Martínez-López, Gustavo A. Folle, L. Méndez-Acuña, Fabrizio Palitti, G. Obe, G. Cassina
Publikováno v:
Cytogenetic and Genome Research. 104:182-187
SORB (selected observed residual breakpoints) induced by ionizing radiation or endonucleases are often non-randomly distributed in mammalian chromosomes. However, the role played by chromatin structure in the localization of chromosome SORB is not we
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::75f6e539bda9b11ad6b31a5a383a3100
https://doi.org/10.1159/000077486
https://doi.org/10.1159/000077486
Autor:
Gustavo A. Folle, Petra Pfeiffer, A.T. Natarajan, P Jeppesen, Wilner Martínez-López, Christian Johannes, Máximo E. Drets, John R.K. Savage, G. Obe, Wolfgang Goedecke
Publikováno v:
Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis. 504:17-36
Chromosomal aberrations (CA) are the microscopically visible part of a wide spectrum of DNA changes generated by different repair mechanisms of DNA double strand breaks (DSB). The method of fluorescence in situ hybridisation (FISH) has uncovered unex
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::428a32b363799455e0332ba85edd6dcd
https://doi.org/10.1016/s0027-5107(02)00076-3
https://doi.org/10.1016/s0027-5107(02)00076-3
Publikováno v:
Radiation Protection Dosimetry. 86:275-278
During long-distance flights at high altitudes flight personnel are exposed to cosmic radiation. In order to determine whether there are biological effects of such low dose radiation exposure in aircrew, chromosomal aberrations were investigated in 5
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2116e959c956e9fb980fbdd4e17da3ef
https://doi.org/10.1093/oxfordjournals.rpd.a032957
https://doi.org/10.1093/oxfordjournals.rpd.a032957
Publikováno v:
International Journal of Radiation Biology. 75:429-433
where dA(t) is the change in A resulting during a Purpose: To estimate the frequencies of dicentric chromosomes in time interval dt from the rate of induction, I(t), and peripheral lymphocytes of astronauts on missions to Mars. the rate of losses, L(
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bf02d75f8dca1c218d54565a8f538e7b
https://doi.org/10.1080/095530099140348
https://doi.org/10.1080/095530099140348
Publikováno v:
International Journal of Radiation Biology. 75:829-836
Purpose: To analyse lymphocyte chromosomes from female cabin attendants flying the North Atlantic route. Materials and methods: Peripheral lymphocytes from 58 cabin attendants and 29 controls, all female, were cultured and analyzed for structural chr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6d82ca555904867acbab05388f8c1c1c
https://doi.org/10.1080/095530099139881
https://doi.org/10.1080/095530099139881
Autor:
R.C. Sobti, G. Obe
It was at the end of the 19th century that a Swiss biologist, Karl Nageli first proposed the existence of hereditary organelles that carried information from parent to offspring. Ensuing decades experienced vigorous studies that led to the developmen