Zobrazeno 1 - 10
of 153
pro vyhledávání: '"G. O'Keeffe"'
Autor:
Edward P. Stern, Lauren V. Host, Ivy Wanjiku, K. Jane Escott, Peter S. Gilmour, Rachel Ochiel, Robert Unwin, Aine Burns, Voon H. Ong, Helen Cadiou, Aidan G. O’Keeffe, Christopher P. Denton
Publikováno v:
Arthritis Research & Therapy, Vol 24, Iss 1, Pp 1-13 (2022)
Abstract Background We report results from a phase II randomised placebo-controlled trial assessing zibotentan, a highly selective endothelin receptor antagonist (ERA), in chronic kidney disease (CKD) secondary to systemic sclerosis (SSc). Methods Th
Externí odkaz:
https://doaj.org/article/e076d30c8d2b4636b01f9033cf571d46
Autor:
Lawrence Peter Binding, Peter Neal Taylor, Aidan G. O'Keeffe, Davide Giampiccolo, Marine Fleury, Fenglai Xiao, Lorenzo Caciagli, Jane de Tisi, Gavin P. Winston, Anna Miserocchi, Andrew McEvoy, John S. Duncan, Sjoerd B. Vos
Publikováno v:
NeuroImage: Clinical, Vol 38, Iss , Pp 103444- (2023)
Background: Anterior temporal lobe resection (ATLR) is a successful treatment for medically-refractory temporal lobe epilepsy (TLE). In the language-dominant hemisphere, 30%- 50% of individuals experience a naming decline which can impact upon daily
Externí odkaz:
https://doaj.org/article/f2cf0710d1d14ddb9034f63c1e7f1da0
Autor:
Kajol Marathe, Ali Alim-Marvasti, Karan Dahele, Fenglai Xiao, Sarah Buck, Aidan G. O'Keeffe, John S. Duncan, Vejay N. Vakharia
Publikováno v:
Frontiers in Neurology, Vol 12 (2021)
Objectives: One-third of individuals with focal epilepsy do not achieve seizure freedom despite best medical therapy. Mesial temporal lobe epilepsy (MTLE) is the most common form of drug resistant focal epilepsy. Surgery may lead to long-term seizure
Externí odkaz:
https://doaj.org/article/20e8d7be662142b9ba0e10f8a19fa21a
Autor:
Jennifer Wenborn, Aidan G O'Keeffe, Gail Mountain, Esme Moniz-Cook, Michael King, Rumana Z Omar, Jacqueline Mundy, Jane Burgess, Fiona Poland, Stephen Morris, Elena Pizzo, Myrra Vernooij-Dassen, David Challis, Susan Michie, Ian Russell, Catherine Sackley, Maud Graff, Tom Swinson, Nadia Crellin, Sinéad Hynes, Jacki Stansfeld, Martin Orrell
Publikováno v:
PLoS Medicine, Vol 18, Iss 1, p e1003433 (2021)
BackgroundWe aimed to estimate the clinical effectiveness of Community Occupational Therapy for people with dementia and family carers-UK version (Community Occupational Therapy in Dementia-UK version [COTiD-UK]) relative to treatment as usual (TAU).
Externí odkaz:
https://doaj.org/article/dcdb25128e4c458e84c27dbbd52789fc
Publikováno v:
BMC Medical Research Methodology, Vol 17, Iss 1, Pp 1-11 (2017)
Abstract Background In healthcare research, outcomes with skewed probability distributions are common. Sample size calculations for such outcomes are typically based on estimates on a transformed scale (e.g. log) which may sometimes be difficult to o
Externí odkaz:
https://doaj.org/article/512d7b6eea5d4fd7ac94bdad5a44d3d4
Autor:
Matteo Mancini, Sjoerd B. Vos, Vejay N. Vakharia, Aidan G. O'Keeffe, Karin Trimmel, Frederik Barkhof, Christian Dorfer, Salil Soman, Gavin P. Winston, Chengyuan Wu, John S. Duncan, Rachel Sparks, Sebastien Ourselin
Publikováno v:
NeuroImage: Clinical, Vol 23, Iss , Pp - (2019)
Diffusion MRI and tractography hold great potential for surgery planning, especially to preserve eloquent white matter during resections. However, fiber tract reconstruction requires an expert with detailed understanding of neuroanatomy. Several auto
Externí odkaz:
https://doaj.org/article/3d70faebc62f4c11ade2400d92dda706
Autor:
John S. Duncan, Aidan G. O'Keeffe, Jane de Tisi, Josemir W. Sander, Shahidul Mannan, Anthony Khoo
Publikováno v:
Epilepsia. 62:2909-2919
Objective: This study was undertaken to determine reasons for adults with drug-resistant focal epilepsy who undergo presurgical evaluation not proceeding with surgery, and to identify predictors of this course. // Methods: We retrospectively analyzed
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a7f7d6de955d2612a622a147de4e1c84
https://doi.org/10.1111/epi.17083
https://doi.org/10.1111/epi.17083
Autor:
Anthony Khoo, Jane de Tisi, Jacqueline Foong, Dorothea Bindman, Aidan G. O’Keeffe, Josemir W. Sander, Anna Miserocchi, Andrew W. McEvoy, John S. Duncan
Objective: Resective surgery for selected individuals with frontal lobe epilepsy can be effective, although multimodal outcomes are less established than in temporal lobe epilepsy. We describe long-term seizure remission and relapse patterns, psychia
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::398e64591e58628e2bab2134547b0be3
Autor:
Andrew W. McEvoy, Vejay N. Vakharia, John S. Duncan, Aidan G. O'Keeffe, Roman Rodionov, Rachel Sparks, Shahrzad Shapoori, Alejandro Granados, Anna Miserocchi, Sebastien Ourselin
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-10 (2021)
Scientific Reports
Scientific Reports
There has been a significant rise in robotic trajectory guidance devices that have been utilised for stereotactic neurosurgical procedures. These devices have significant costs and associated learning curves. Previous studies reporting devices usage
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2bc3dd6e5965632362d6026f452aaca3
https://doaj.org/article/d16a8c5114074d2d860a1e1a0e6ab418
https://doaj.org/article/d16a8c5114074d2d860a1e1a0e6ab418
Autor:
Aidan G. O'Keeffe, Vejay N. Vakharia, Michele Rizzi, Mark Nowell, Andrew W. McEvoy, Victoria Wykes, Sofia H Eriksson, Anna Miserocchi, Roman Rodionov, Sebastien Ourselin, John S. Duncan
Publikováno v:
Journal of Neurosurgery. 133:35-42
OBJECTIVEThe accuracy of stereoelectroencephalography (SEEG) electrode implantation is an important factor in maximizing its safety. The authors established a quality assurance (QA) process to aid advances in implantation accuracy.METHODSThe accuracy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1914f3d1a2e579e63d4bde7d230a5953
https://doi.org/10.3171/2019.2.jns183313
https://doi.org/10.3171/2019.2.jns183313