Zobrazeno 1 - 9
of 9
pro vyhledávání: '"G. Nicholas Llewellyn"'
Publikováno v:
PLoS Pathogens, Vol 6, Iss 10, p e1001167 (2010)
T cells adopt a polarized morphology in lymphoid organs, where cell-to-cell transmission of HIV-1 is likely frequent. However, despite the importance of understanding virus spread in vivo, little is known about the HIV-1 life cycle, particularly its
Externí odkaz:
https://doaj.org/article/4b2f16bf55cb4dd48580c14c9c312120
Autor:
Jonathan R. Grover, Kunio Nagashima, Ferri Soheilian, Sarah L. Veatch, G. Nicholas Llewellyn, Akira Ono
Publikováno v:
Journal of Virology. 87:4650-4664
Tetherin/BST-2 (here called tetherin) is an antiviral protein that restricts release of diverse enveloped viruses from infected cells through physically tethering virus envelope and host plasma membrane. For HIV-1, specific recruitment of tetherin to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5b91d942546341e57bd4930dfe50e2f3
https://doi.org/10.1128/jvi.03526-12
https://doi.org/10.1128/jvi.03526-12
Autor:
Paula M. Cannon, Joshua J. DeClercq, Jianbin Wang, Philip D. Gregory, Colin M. Exline, Samuel B. Hayward, Richard T. Surosky, David A. Shivak, G. Nicholas Llewellyn, Michael C. Holmes, Patrick Li
Publikováno v:
Nature biotechnology
Genome editing with targeted nucleases and DNA donor templates homologous to the break site has proven challenging in human hematopoietic stem and progenitor cells (HSPCs), and particularly in the most primitive, long-term repopulating cell populatio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::255407628e9aa3377c850dda51a7bdc0
https://pubmed.ncbi.nlm.nih.gov/26551060
https://pubmed.ncbi.nlm.nih.gov/26551060
In polarized T cells, HIV-1 Gag localizes to a rear-end protrusion known as the uropod in a multimerization-dependent manner. Gag-laden uropods participate in formation of virological synapses, intercellular contact structures that play a key role in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5f12601e590fdf67202733e0c60a714a
https://europepmc.org/articles/PMC3648103/
https://europepmc.org/articles/PMC3648103/
Publikováno v:
Molecular Biology International
HIV-1 particle assembly is driven by the structural protein Gag. Gag binds to and multimerizes on the inner leaflet of the plasma membrane, eventually resulting in formation of spherical particles. During virus spread among T cells, Gag accumulates t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::38d8a60ff2b1a094032c9686ee453e72
https://pubmed.ncbi.nlm.nih.gov/22830021
https://pubmed.ncbi.nlm.nih.gov/22830021
Autor:
Lynne M. Bianchi, Andrew P. Chervenak, Ethan M. Jewett, Alicia E. Koch, Jennifer Benson, Kate F. Barald, Ariane Kanicki, Christine R. Beck, Catherine A. Martin, Matthew Flynn, Ryan S. Teller, Stephanie A. Linn, G. Nicholas Llewellyn, Jaeda Coutinho-Budd, Yu Chi Shen, John A. Germiller, Luming Feng, Brandon B. Holmes, Cyrrene Sharples, Fumi Ebisu, Dov Lerman-Sinkoff, Lisa M. Bank, Therese M. Roth, Elizabeth Smiley, Richard A. Altschuler, David F. Dolan, Deborah L. Thompson, Poornapriya Ramamurthy
Publikováno v:
Development. 140:479-479
This study is the first to demonstrate that macrophage migration inhibitory factor (MIF), an immune system ‘inflammatory’ cytokine that is released by the developing otocyst, plays a role in regulating early innervation of the mouse and chick inn
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::14a0220b6f6fece3626120a43b472ced
https://doi.org/10.1242/dev.092486
https://doi.org/10.1242/dev.092486
Publikováno v:
PLoS Pathogens, Vol 6, Iss 10, p e1001167 (2010)
PLoS Pathogens
PLoS Pathogens
T cells adopt a polarized morphology in lymphoid organs, where cell-to-cell transmission of HIV-1 is likely frequent. However, despite the importance of understanding virus spread in vivo, little is known about the HIV-1 life cycle, particularly its
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6f1f8474a2938833a8aad9e06ad39f7f
https://doi.org/10.1371/journal.ppat.1001167
https://doi.org/10.1371/journal.ppat.1001167
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Akademický článek
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