Zobrazeno 1 - 10
of 18
pro vyhledávání: '"G. Neil Stowe"'
Publikováno v:
Journal of Analytical Toxicology. 47:197-205
Amphetamines (AMPs) in hair were investigated with thousands of workplace testing head and body hair samples collected and analyzed over 10 years and tabulated by year. All samples were washed by a published extensive method prior to confirmation by
Publikováno v:
Journal of Analytical Toxicology. 46:487-493
The cannabinoids tetrahydrocannabinol (THC), tetrahydrocannabivarin (THCV), cannabidiol (CBD), cannabinol (CBN) and (-)-11-nor-9-carboxy-∆9-tetrahydrocannabinol (THC-COOH) were determined in 4,773 hair samples. Confirmation of THC-COOH was by GC–
Publikováno v:
Forensic science international. 317
Hydroxycocaines in hair were investigated with many hundreds of head and body hair samples. All samples were washed by a published extensive aqueous method prior to confirmation by LC-MS/MS. Concentrations, percent of cocaine, and ratios of para- and
Publikováno v:
Journal of Analytical Toxicology. 40:345-349
The presence of the metabolite 11-nor-9-carboxy-delta-9-tetrahydrocannabinol (C-THC) in hair is generally accepted as the definitive proof of delta-9-tetrahydrocannabinol (THC) ingestion. During hair analysis, the removal of any potential C-THC exter
Publikováno v:
Journal of analytical toxicology. 43(7)
Opioids, both naturally occurring and semisynthetic, are effective pain management medications, but also possess the potential for abuse. Analyses of over 37,000 head and body hair samples containing codeine, morphine, hydrocodone, hydromorphone, oxy
Publikováno v:
Journal of analytical toxicology. 42(6)
Analysis of nail clippings may be a useful back-up for hair analysis when hair is unavailable. One aspect of using nails or hair is the ability to analyze whether drug present is from ingestion or from contamination. A common method of three 15-s rin
Autor:
Sabine Pellett, B. Blanco, Kim D. Janda, Eric A. Johnson, G. Neil Stowe, Peter Šilhár, Matthew Lardy, Hajime Seki
Publikováno v:
Bioorganic & Medicinal Chemistry. 22:1208-1217
Botulinum neurotoxin A (BoNT/A) is the most potent toxin known. Unfortunately, it is also a potential bioweapon in terrorism, which is without an approved therapeutic treatment once cellular intoxication takes place. Previously, we reported how hydro
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Autor:
Kim D. Janda, G. Neil Stowe, Leandro F. Vendruscolo, Joel E. Schlosburg, George F. Koob, Scott Edwards, Jonathan W. Lockner, Ashlee A. K. Nunes, Paul T. Bremer, Carrie L. Wade
Publikováno v:
Proceedings of the National Academy of Sciences. 110:9036-9041
Heroin addiction, a chronic relapsing disorder characterized by excessive drug taking and seeking, requires constant psychotherapeutic and pharmacotherapeutic interventions to minimize the potential for further abuse. Vaccine strategies against many
Autor:
Young Jun Kang, Peter S. Tobias, G. Neil Stowe, Kim D. Janda, Gunnar F. Kaufmann, Vladimir V. Kravchenko, Christian Gloeckner, John C. Mathison, Richard J. Ulevitch
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 22:2043-2045
Simultaneous activation of signaling pathways requires dynamic assembly of higher-order protein complexes at the cytoplasmic domains of membrane-associated receptors in a stimulus-specific manner. Here, using the paradigm of cellular activation throu