Výsledky vyhledávání - "G. N. Sastry"

Akademický článek

Stability estimation through multivariate approach among solasodine-rich lines of Solanum khasianum (C.B. Clarke): an important industrial plant

Autor: Twahira Begum, Sunita Munda, Tanmita Gupta, Roktim Gogoi, Vikash Kumar Choubey, Sanjoy K. Chanda, Himangshu Lekhak, G. N. Sastry, Mohan Lal

Publikováno v: Frontiers in Plant Science, Vol 14 (2023)

Solanum khasianum is a medicinally important plant that is a source of steroidal alkaloids ‘solasodine.’ It has various industrial applications, including oral contraceptives and other pharmaceutical uses. The present study was based on 186 germp

Externí odkaz: https://doaj.org/article/1cdb02344ec243a288c3174f86fc95e7

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How good are publicly available web services that predict bioactivity profiles for drug repurposing?

Autor: Dmitry S. Druzhilovskiy, Vladimir Poroikov, Khalimat Murtazalieva, G N Sastry, Rajesh Kumar Goel

Publikováno v: SAR and QSAR in Environmental Research. 28:843-862

Drug repurposing provides a non-laborious and less expensive way for finding new human medicines. Computational assessment of bioactivity profiles shed light on the hidden pharmacological potential of the launched drugs. Currently, several freely ava

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c6ac1b52e89f499e01bda54d1f772872
https://doi.org/10.1080/1062936x.2017.1399448

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Web Resources for Discovery and Development of New Medicines

Autor: G N Sastry, Vladimir Poroikov, Dmitry Filimonov, Sergey Ivanov, D. S. Druzhilovskii, V. M. Bezhentsev

Publikováno v: Pharmaceutical Chemistry Journal. 51:91-99

Modern drug discovery is based on the analysis of information about disease mechanisms, molecular targets, and pharmacological substances, the action of which helps to normalize pathological processes. Existing chemical and biomedical databases have

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::0c02073923820925cf27194b98efa888
https://doi.org/10.1007/s11094-017-1563-x

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Molecular property diagnostic suite (MPDS): Development of disease-specific open source web portals for drug discovery

Autor: S. Nagamani, A. S. Gaur, K. Tanneeru, G. Muneeswaran, S. S. Madugula, MPDS Consortium, D. Druzhilovskiy, V. V. Poroikov, G. N. Sastry

Publikováno v: SAR and QSAR in environmental research. 28(11)

Molecular property diagnostic suite (MPDS) is a Galaxy-based open source drug discovery and development platform. MPDS web portals are designed for several diseases, such as tuberculosis, diabetes mellitus, and other metabolic disorders, specifically

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::15b27251debbd0818b299310c6962cc5
https://pubmed.ncbi.nlm.nih.gov/29206500

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How good are publicly available web services that predict bioactivity profiles for drug repurposing?$

Autor: K. A. Murtazalieva, D. S. Druzhilovskiy, R. K. Goel, G. N. Sastry, V. V. Poroikov

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a5b904f971f6feaafbda01c184dd4954

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Choline Kinase: An Important Target for Cancer

Autor: Sridhara Janardhan, P. Srivani, G. N. Sastry

Publikováno v: Current Medicinal Chemistry. 13:1169-1186

Choline kinase (ChoK) is a cytosolic enzyme present in various tissues, which catalyzes the phosphorylation of choline to form phosphorylcholine (PCho) in the presence of ATP and magnesium. ChoK is important for the generation of two major membrane p

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c0abcb3c2422b0700568300da8ecfa6f
https://doi.org/10.2174/092986706776360923

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Differentiation of isomeric 2-aryldimethyltetrahydro-5-quinolinones by electron ionization and electrospray ionization mass spectrometry

Autor: Ch Dinesh, Kumar, V Naresh, Chary, A, Dinesh, P S, Reddy, K, Srinivas, G, Gayatri, G N, Sastry, S, Prabhakar

Publikováno v: Rapid communications in mass spectrometry : RCM. 25(19)

A series of isomeric 2-aryl-6,6-dimethyltetrahydro-5-quinolinones (set I) and 2-aryl-7,7-dimethyltetrahydro-5-quinolinones (set II) were studied under positive ion electron ionization (EI) and electrospray ionization (ESI) techniques. Under EI condit

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::6b7d18864a733131cb668af65adfdb25
https://pubmed.ncbi.nlm.nih.gov/21913260

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