Zobrazeno 1 - 10
of 66
pro vyhledávání: '"G. N. Gill"'
Publikováno v:
BRICS Law Journal, Vol 8, Iss 2, Pp 10-40 (2021)
The Covid-19 narrative spotlights the necessity to conserve biological diversity (biodiversity) including ecosystems and wildlife. Biodiversity problems are global, and associated governance issues range beyond geographical and spatial boundaries. Th
Externí odkaz:
https://doaj.org/article/5ab78a223cee45639ba3e6202da6edad
Autor:
Xiaoman Xu, Bogi Andersen, R Newton, Zhongxian Lu, Ning Wang, Kevin K. Lin, G N Gill, Zhengquan Yu, Kit S. Lam
Publikováno v:
Oncogene. 26:6431-6441
The nuclear LIM-only protein 4 (LMO4) is upregulated in breast cancer, especially estrogen receptor-negative tumors, and its overexpression in mice leads to hyperplasia and tumor formation. Here, we show that deletion of LMO4 in the mammary glands of
Publikováno v:
Journal of Biological Chemistry. 268:26978-26982
The intrinsic protein tyrosine kinase activity of the epidermal growth factor (EGF) receptor is necessary for ligand-induced signaling. To determine whether cellular protein tyrosine kinases are substrates for EGF-activated receptors, phosphotyrosine
Publikováno v:
Scopus-Elsevier
Occupancy-induced down-regulation of cell surface epidermal growth factor (EGF) receptors attenuates signal transduction. To define mechanisms through which down-regulation of this class of growth factor receptors occurs, we have investigated the rel
Autor:
L W, Jurata, G N, Gill
Publikováno v:
Current topics in microbiology and immunology. 228
Publikováno v:
The Journal of biological chemistry. 271(9)
Increased expression of the protein-tyrosine kinase receptor ErbB-2 occurs frequently in human breast and ovarian cancer and causes transformation in experimental systems. Control of transcription of the erbB-2 gene is an important determinant of rec
Publikováno v:
Oncogene. 10(4)
Several signal transducers bind through their SH2 domains to phosphotyrosine-containing motifs present in receptor tyrosine kinases (RTKs). However, the juxtamembrane regions of the epidermal growth factor receptor (EGFR) and of the related erbB-2 pr
Publikováno v:
The Journal of biological chemistry. 269(40)
Endocytosis of cell surface receptors requires sequence "codes" consisting of tight turn structures with an essential Tyr or Phe residue. To determine mechanisms through which cells recognize this information, we utilized exon 16 of the human insulin
Publikováno v:
Oncogene. 9(8)
Analysis of the proximal promoter of the human erbB-2 gene identified a 100 bp region that enhanced activity of the proximal TATA box 200-fold. DNase I footprinting mapped three Sp1 binding sites within this 100 bp region but only one of these sites
Publikováno v:
The Journal of biological chemistry. 269(1)
The intracellular portion of the epidermal growth factor receptor consists of a tyrosine kinase domain of approximately 290 amino acids and a COOH-terminal regulatory domain of approximately 230 amino acids that contains five sites of autophosphoryla