Zobrazeno 1 - 10
of 111
pro vyhledávání: '"G. Michael Vincent"'
Autor:
G. Michael Vincent
Publikováno v:
Indian Pacing and Electrophysiology Journal, Vol 2, Iss 4, Pp 127-142 (2002)
The Long QT syndrome (LQTS) can be inherited or acquired and is of particular interest and concern at present. Patients with LQTS are predisposed to the ventricular tachyarrhythmia torsade de pointes (TdP) which causes syncope and sudden death. Inher
Externí odkaz:
https://doaj.org/article/cd8d482dc2bd4d459e25c7c47bdbef9e
Autor:
Arthur A.M. Wilde, Jeffrey A. Towbin, Arthur J. Moss, Emanuela H. Locati, G. Michael Vincent, Scott McNitt, Michael J. Ackerman, Jesaia Benhorin, Ilan Goldenberg, Alon Barsheshet, Ming Qi, Elizabeth S. Kaufman, Pyotr G. Platonov, Andrew Mathias, Li Zhang, Coeli M. Lopes, Jennifer L. Robinson, Wojciech Zareba, Wataru Shimizu
Publikováno v:
Heart rhythm, 10(5), 720-725. Elsevier
Individual corrected QT interval (QTc) may vary widely among carriers of the same long QT syndrome (LQTS) mutation. Currently, neither the mechanism nor the implications of this variable penetrance are well understood. To hypothesize that the assessm
Autor:
Wojciech Zareba, Wataru Shimizu, Arthur A.M. Wilde, Derick R. Peterson, G. Michael Vincent, Jennifer L. Robinson, Arthur J. Moss, Jin O-Uchi, Pyotr G. Platonov, Jørgen K. Kanters, Nynke Hofman, Jeffrey A. Towbin, Ilan Goldenberg, Alon Barsheshet, Christian Jons, Elizabeth S. Kaufman, Ming Qi, Coeli M. Lopes, Scott McNitt, Michael J. Ackerman, Michael W. Cypress, Daniel A. Gray
Publikováno v:
Circulation, 125(16), 1988-+. Lippincott Williams and Wilkins
Background— β-Adrenergic stimulation is the main trigger for cardiac events in type 1 long-QT syndrome (LQT1). We evaluated a possible association between ion channel response to β-adrenergic stimulation and clinical response to β-blocker therap
Autor:
Jennifer L. Robinson, Coeli M. Lopes, Ming Qi, Michael J. Ackerman, Scott McNitt, Arthur J. Moss, Slava Polonsky, Wojciech Zareba, Jeffrey A. Towbin, G. Michael Vincent, Ilan Goldenberg, Alon Barsheshet, Elizabeth S. Kaufman, Jesaia Benhorin
Publikováno v:
Circulation: Cardiovascular Genetics. 4:491-499
Background— Current clinical diagnosis of long-QT syndrome (LQTS) includes genetic testing of family members of mutation-positive patients. The present study was designed to assess the clinical course of individuals who are found negative for the L
Autor:
Michael J. Ackerman, Derick R. Peterson, G. Michael Vincent, Jesaia Benhorin, Arthur J. Moss, Peter J. Schwartz, Ilan Goldenberg, Alon Barsheshet, Li Zhang, Elizabeth S. Kaufman, Jeffrey A. Towbin, Jennifer L. Robinson, Scott McNitt, Wojciech Zareba, Jonathan Buber, Slava Polonsky
Publikováno v:
Heart Rhythm. 8:1207-1213
Background A prolonged QT interval corrected for heart rate (QTc) is a major risk factor in patients with long QT syndrome (LQTS). However, heart rate–related risk in this genetic disorder differs among genotypes. Objective This study hypothesized
Autor:
Thomas Fugate, Gregory M. Ouellet, Carla Spazzolini, Peter J. Schwartz, Arthur J. Moss, Lia Crotti, Jennifer L. Robinson, Jamie Mullally, Wojciech Zareba, Scott McNitt, Silvia G. Priori, Christian Jons, Jesaia Benhorin, Jeffrey A. Towbin, Ming Qi, Ilan Goldenberg, G. Michael Vincent, Emanuela H. Locati, Elizabeth S. Kaufman, Michael J. Ackerman, Carlo Napolitano
Publikováno v:
Journal of the American College of Cardiology. 54:832-837
Objectives: This study was designed to evaluate the clinical and prognostic aspects of long QT syndrome (LQTS)-related cardiac events that occur in the first year of life (infancy). Background: The clinical implications for patients with long QT synd
Autor:
G. Michael Vincent
Publikováno v:
Pacing and Clinical Electrophysiology. 32:S19-S22
Background: Sudden cardiac arrest in the young is always an extremely tragic event, producing enormous stress and anxiety in the family. When the event is due to an inherited cardiac arrhythmia, the additional concerns and questions about who else is
Autor:
Candice Bithell, Silvia G. Priori, Carlo Napolitano, Li Zhang, Heikki Swan, Carla Spazzolini, Peter J. Schwartz, Isabelle Denjoy, G. Michael Vincent, Kirsi Piippo, Villain E, Lia Crotti, Jean Marc Lupoglazoff
Publikováno v:
Circulation. 119:215-221
Background— β-Blocker efficacy in long-QT syndrome type 1 is good but variably reported, and the causes of cardiac events despite β-blocker therapy have not been ascertained. Methods and Results— This was a retrospective study of the details su
Autor:
Ilan Goldenberg, Michael J. Ackerman, Wojciech Zareba, Shiro Kamakura, Elizabeth S. Kaufman, Scott McNitt, Ming Qi, Samit Shah, Arthur J. Moss, Yoshihiro Miyamoto, Vinit Amin, Jennifer L. Robinson, Craig T. January, G. Michael Vincent, Wataru Shimizu, Nynke Hofman, Mark L. Andrews, Takashi Noda, Arthur A.M. Wilde, Jeffrey A. Towbin, David J. Tester
Publikováno v:
Journal of the American College of Cardiology, 54(22), 2052-2062. Elsevier USA
Objectives The purpose of this study was to investigate the effect of location, coding type, and topology of KCNH2(hERG) mutations on clinical phenotype in type 2 long QT syndrome (LQTS). Background Previous studies were limited by population size in
Autor:
G. Michael Vincent
Publikováno v:
Circulation: Arrhythmia and Electrophysiology. 1:227-233
Genotyping has led to enormous advances in understanding the phenotype and clinical course of the congenital long-QT syndromes (LQTS). In the most common LQTS forms, LQT1, LQT2, and LQT3, genotyping a clearly affected person in each family provides t