Zobrazeno 1 - 10
of 400
pro vyhledávání: '"G. Mengod"'
Early L-dopa, but not pramipexole, restores basal ganglia activity in partially 6-OHDA-lesioned rats
Publikováno v:
Neurobiology of Disease, Vol 64, Iss , Pp 36-47 (2014)
The most appropriate time for the initiation of dopaminergic symptomatic therapy in Parkinson's disease remains debatable. It has been suggested that early correction of basal ganglia pathophysiological abnormalities may have long-term beneficial eff
Externí odkaz:
https://doaj.org/article/ac0e703ba1b54140b4e63da17cc5a6a8
Publikováno v:
Neurobiology of Disease, Vol 32, Iss 3, Pp 340-348 (2008)
Coadministration of entacapone with levodopa attenuates motor complications in experimental models of Parkinson's disease. The mechanisms underlying entacapone effects are unknown. We investigated the effect of entacapone, on: long-duration response
Externí odkaz:
https://doaj.org/article/7c1c8eab79cf4790b9dbdf319e1ce139
Autor:
L.C. Triarhou, C. Solà, G. Mengod, F.J. García-Ladona, B. Landwehrmeyer, B. Ghetti, J. M. Palacios
Publikováno v:
Cell Transplantation, Vol 4 (1995)
Mesencephalic cell suspensions were prepared from E12 wild-type (+/+) mouse embryos and stereotaxically implanted into the dorsal neostriatum of weaver mutant mice (wv/wv), which have a genetic mesostriatal dopamine (DA) deficiency. Survival of DA ne
Externí odkaz:
https://doaj.org/article/7c2398f299e74736bf92517db27171d7
Publikováno v:
SITES of DRUG ACTION in the HUMAN BRAIN
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::34fc30393c7e6bba7d05df9475fc123d
https://doi.org/10.1201/9780367811419-2
https://doi.org/10.1201/9780367811419-2
Autor:
S. Pérez-Torres, G. Mengod
Publikováno v:
International Congress Series. 1251:127-138
Cyclic nucleotide signaling controls a wide variety of cellular functions. Phosphodiesterases (PDEs) regulate the intracellular levels of cAMP and cGMP, thus playing an important role in signal transduction. It has been observed that PDE4 inhibition
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d6cb4a69bd667295efb1c5d952795f44
https://doi.org/10.1016/s0531-5131(03)00104-3
https://doi.org/10.1016/s0531-5131(03)00104-3
Autor:
Avi Ashkenazi, A. M. V. Duncan, Richard Rozmahel, Brian F. O'Dowd, G. Mengod, S. J. Peroutka, J. M. Palacios, Yilli Yang, Hui Jin, D. Oksenberg
Publikováno v:
Scopus-Elsevier
We report the cloning of a human gene encoding the 5-hydroxytryptamine1B receptor. The receptor has the characteristics of a G-protein-linked receptor and is most homologous to the human 5-HT1D receptor. This human 5-HT receptor gene, most abundantly
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b9e48623d87fb3ee3be1c833e241e85f
https://doi.org/10.1016/s0021-9258(18)42612-9
https://doi.org/10.1016/s0021-9258(18)42612-9
Autor:
J, de Almeida, G, Mengod
Publikováno v:
Journal of neurochemistry. 103(2)
5-hydroxytryptamine (5-HT) or serotonin 2A receptors play an important role in modulation of prefrontal cortex (PFC) activity and have been implicated in the physiopathology of psychiatric disorders. There is no quantitative information on the percen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::d4020bc644363899f7f09bdfc39316a8
https://pubmed.ncbi.nlm.nih.gov/17635672
https://pubmed.ncbi.nlm.nih.gov/17635672
Publikováno v:
The European journal of neuroscience. 25(1)
The long-duration response (LDR) is a sustained improvement in parkinsonism due to chronic levodopa therapy and lasts after discontinuation of treatment. We have investigated the molecular changes that underlie the LDR in rats with a unilateral 6-hyd
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::d7c5c8eda39837d2de0f70cdb6087edc
https://pubmed.ncbi.nlm.nih.gov/17241287
https://pubmed.ncbi.nlm.nih.gov/17241287
Publikováno v:
Journal of neural transmission (Vienna, Austria : 1996). 109(11)
The distribution of mRNAs encoding for somatostatin, cholecystokinin and neuropeptide Y was determined by in situ hybridization histochemistry in the weaver (wv/wv) mouse, a model of dopamine deficiency as well as in normal (+/+) controls. Weaver mut
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::f97850a1320bc9267d805b881a89f794
https://pubmed.ncbi.nlm.nih.gov/12454731
https://pubmed.ncbi.nlm.nih.gov/12454731
Publikováno v:
Synapse (New York, N.Y.). 42(1)
The distribution of serotonin 5-HT(2C) receptor mRNA in monkey brain was studied by in situ hybridization and compared with the distribution of [3H]mesulergine binding sites as visualized by receptor autoradiography. 5-HT(2C) receptor transcripts sho
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::0e3fdf04bdf70410432eda8eed859efb
https://pubmed.ncbi.nlm.nih.gov/11668587
https://pubmed.ncbi.nlm.nih.gov/11668587