Zobrazeno 1 - 10
of 304
pro vyhledávání: '"G. McEwen"'
Autor:
Fergal J. Duffy, January Weiner, Scott Hansen, David L. Tabb, Sara Suliman, Ethan Thompson, Jeroen Maertzdorf, Smitha Shankar, Gerard Tromp, Shreemanta Parida, Drew Dover, Michael K. Axthelm, Jayne S. Sutherland, Hazel M. Dockrell, Tom H. M. Ottenhoff, Thomas J. Scriba, Louis J. Picker, Gerhard Walzl, Stefan H. E. Kaufmann, Daniel E. Zak, The GC6-74 Consortium, S. H. E. Kaufmann, S. K. Parida, R. Golinski, J. Maertzdorf, J. Weiner, M. Jacobson, G. McEwen, G. Walzl, G. F. Black, G. van der Spuy, K. Stanley, M. Kriel, N. Du Plessis, N. Nene, A. G. Loxton, N. N. Chegou, S. Suliman, T. Scriba, M. Fisher, H. Mahomed, J. Hughes, K. Downing, A. Penn-Nicholson, H. Mulenga, B. Abel, M. Bowmaker, B. Kagina, W. Kwong, C. W. Hanekom, T. H. M. Ottenhoff, M. R. Klein, M. C. Haks, K. L. Franken, A. Geluk, K. E. van Meijgaarden, S. A. Joosten, D. van Baarle, F. Miedema, W. H. Boom, B. Thiel, J. Sadoff, D. Sizemore, S. Ramachandran, L. Barker, M. Brennan, F. Weichold, S. Muller, L. Geiter, G. Schoolnik, G. Dolganov, T. Van, H. Mayanja-Kizza, M. Joloba, S. Zalwango, M. Nsereko, B. Okwera, H. Kisingo, H. M. Dockrell, S. Smith, P. Gorak-Stolinska, Y.-G. Hur, M. Lalor, J.-S. Lee, A. C. Crampin, N. French, B. Ngwira, A. B. Smith, K. Watkins, L. Ambrose, F. Simukonda, H. Mvula, F. Chilongo, J. Saul, K. Branson, D. Kassa, A. Abebe, T. Mesele, B. Tegbaru, R. Howe, A. Mihret, A. Aseffa, Y. Bekele, R. Iwnetu, M. Tafesse, L. Yamuah, M. Ota, J. Sutherland, P. Hill, R. Adegbola, T. Corrah, M. Antonio, T. Togun, I. Adetifa, S. Donkor, P. Andersen, I. Rosenkrands, M. Doherty, K. Weldingh
Publikováno v:
Frontiers in Immunology, Vol 10 (2019)
There remains a pressing need for biomarkers that can predict who will progress to active tuberculosis (TB) after exposure to Mycobacterium tuberculosis (MTB) bacterium. By analyzing cohorts of household contacts of TB index cases (HHCs) and a string
Externí odkaz:
https://doaj.org/article/1eba36dc045c44aa95b786e37918a63e
Autor:
Changqing Li, Stefano Moro, Kateryna Shostak, Francis J. O’Reilly, Mariel Donzeau, Andrea Graziadei, Alastair G. McEwen, Dominique Desplancq, Pierre Poussin-Courmontagne, Thomas Bachelart, Mert Fiskin, Nicolas Berrodier, Simon Pichard, Karl Brillet, Georges Orfanoudakis, Arnaud Poterszman, Vladimir Torbeev, Juri Rappsilber, Norman E. Davey, Alain Chariot, Katia Zanier
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-19 (2024)
Abstract The inhibitor of κB (IκB) kinase (IKK) is a central regulator of NF-κB signaling. All IKK complexes contain hetero- or homodimers of the catalytic IKKβ and/or IKKα subunits. Here, we identify a YDDΦxΦ motif, which is conserved in subs
Externí odkaz:
https://doaj.org/article/7002b32fa22e4bd38f05d9ec9d049537
Autor:
Fergal J. Duffy, Ethan Thompson, Katrina Downing, Sara Suliman, Harriet Mayanja-Kizza, W. Henry Boom, Bonnie Thiel, January Weiner III, Stefan H. E. Kaufmann, Drew Dover, David L. Tabb, Hazel M. Dockrell, Tom H. M. Ottenhoff, Gerard Tromp, Thomas J. Scriba, Daniel E. Zak, Gerhard Walzl, the GC6-74 Consortium, S. H. E. Kaufmann, S. K. Parida, R. Golinski, J. Maertzdorf, J. Weiner, M. Jacobson, G. McEwen, G. Walzl, G. Black, G. van der Spuy, K. Stanley, M. Kriel, N. Du Plessis, N. Nene, A. Loxton, N. N. Chegou, S. Suliman, T. Scriba, H. Mahomed, M. Erasmus, O. Xasa, A. Veldsman, J. Hughes, K. Downing, A. Penn-Nicholson, H. Mulenga, B. Abel, M. Bowmaker, B. Kagina, W. Kwong C, W. Hanekom, T. H. M. Ottenhoff, M. R. Klein, M. C. Haks, K. L. Franken, A. Geluk, K. E. van Meijgaarden, S. A. Joosten, D. van Baarle, F. Miedema, W. H. Boom, B. Thiel, J. Sadoff, D. Sizemore, S. Ramachandran, L. Barker, M. Brennan, F. Weichold, S. Muller, L. Geiter, G. Schoolnik, G. Dolganov, T. Van, H. Mayanja-Kizza, M. Joloba, S. Zalwango, M. Nsereko, B. Okwera, H. Kisingo, H. Dockrell, S. Smith, P. Gorak-Stolinska, Y.-G. Hur, M. Lalor, J.-S. Lee, A. C. Crampin, N. French, B. Ngwira, A. B. Smith, K. Watkins, L. Ambrose, F. Simukonda, H. Mvula, F. Chilongo, J. Saul, K. Branson, D. Kassa, A. Abebe, T. Mesele, B. Tegbaru, R. Howe, A. Mihret, A. Aseffa, Y. Bekele, R. Iwnetu, M. Tafesse, L. Yamuah, M. Ota, J. Sutherland, P. Hill, R. Adegbola, T. Corrah, M. Antonio, T. Togun, I. Adetifa, S. Donkor, P. Andersen, I. Rosenkrands, M. Doherty, K. Weldingh
Publikováno v:
Frontiers in Immunology, Vol 9 (2018)
Biomarkers that predict who among recently Mycobacterium tuberculosis (MTB)-exposed individuals will progress to active tuberculosis are urgently needed. Intracellular microRNAs (miRNAs) regulate the host response to MTB and circulating miRNAs (c-miR
Externí odkaz:
https://doaj.org/article/a450c97d56b9481c89cbc4507d35a4ef
Autor:
Lina M. Osorio-Cock, Sandra Catalina Jaramillo-Pulgarín, Alba P. Ferrín-Bastidas, Diana Y. Molina-Colorado, Óscar M. Gómez-Guzmán, Alejandra Zuluaga, Juan G. McEwen-Ochoa, Martha E. Urán-Jiménez, María del Pilar Jiménez-Alzate
Publikováno v:
Biomédica: revista del Instituto Nacional de Salud, Vol 43, Iss Sp. 1, Pp 69-76 (2023)
La paracoccidioidomicosis es una micosis sistémica endémica en Latinoamérica. La presentación más frecuente compromete crónicamente los pulmones, la piel y las mucosas. Al inicio, este paciente presentó, por varios años, una lesión única en
Externí odkaz:
https://doaj.org/article/9230dd1314144951816f90a072673b46
Autor:
Laura C. Álvarez-Acevedo, María C. Zuleta-González, Óscar M. Gómez-Guzmán, Álvaro L. Rúa-Giraldo, Orville Hernández-Ruiz, Juan G. McEwen-Ochoa, Martha E. Urán-Jiménez, Myrtha Arango-Arteaga, Rosely M. Zancopé-Oliveira, Manoel Marques Evangelista de Oliveira, María del P. Jiménez-Alzate
Publikováno v:
Biomédica: revista del Instituto Nacional de Salud, Vol 43, Iss Sp. 1, Pp 216-228 (2023)
Introduction. For over a century, Sporothrix schenckii was considered the sole species responsible for sporotrichosis. In 2007, scientific community confirmed the disease could be caused by various Sporothrix species. These species differed in their
Externí odkaz:
https://doaj.org/article/142409104cd740089e2478e672cb3cab
Autor:
Isaura Torres, Juan E. Gallo, Oscar Mauricio Gómez, Álvaro Rúa-Giraldo, Juan G. McEwen, Ana María García
Publikováno v:
Biomédica: revista del Instituto Nacional de Salud, Vol 42, Iss 4, Pp 697-706 (2022)
Introducción. El fluconazol es el antifúngico más utilizado para la prevención y el tratamiento de infecciones causadas por el género Cryptococcus, agente etiológico de la criptococosis. La resistencia al fluconazol en los aislamientos de Crypt
Externí odkaz:
https://doaj.org/article/5e6f3c512b614e8e849df8d59d4fa3c6
Autor:
Brice Beinsteiner, Gabriel V. Markov, Maxime Bourguet, Alastair G. McEwen, Stéphane Erb, Abdul Kareem Mohideen Patel, Fatima Z. El Khaloufi El Khaddar, Claire Lecroisey, Guillaume Holzer, Karim Essabri, Isabelle Hazemann, Ali Hamiche, Sarah Cianférani, Dino Moras, Vincent Laudet, Isabelle M. L. Billas
Publikováno v:
BMC Biology, Vol 20, Iss 1, Pp 1-19 (2022)
Abstract Background Nuclear receptors are transcription factors of central importance in human biology and associated diseases. Much of the knowledge related to their major functions, such as ligand and DNA binding or dimerization, derives from funct
Externí odkaz:
https://doaj.org/article/a92389b629514a4e8a6968a1a1cd396d
Publikováno v:
Molecules, Vol 28, Iss 11, p 4407 (2023)
Staphylococcus aureus is a common opportunistic pathogen of humans and livestock that causes a wide variety of infections. The success of S. aureus as a pathogen depends on the production of an array of virulence factors including cysteine proteases
Externí odkaz:
https://doaj.org/article/cef506fc217f40b0b0efce17337702ba
Autor:
João Eudes Filho, Isabele Barbieri dos Santos, Carmélia Matos Santiago Reis, José Salvatore Leister Patané, Verenice Paredes, João Paulo Romualdo Alarcão Bernardes, Sabrina dos Santos Costa Poggiani, Talita de Cássia Borges Castro, Oscar Mauricio Gomez, Sandro Antonio Pereira, Edvar Yuri Pacheco Schubach, Kamila Peres Gomes, Heidi Mavengere, Lucas Gomes de Brito Alves, Joaquim Lucas, Hugo Costa Paes, Patrícia Albuquerque, Laurício Monteiro Cruz, Juan G. McEwen, Jason E. Stajich, Rodrigo Almeida-Paes, Rosely Maria Zancopé-Oliveira, Daniel R. Matute, Bridget M. Barker, Maria Sueli Soares Felipe, Marcus de Melo Teixeira, André Moraes Nicola
Publikováno v:
Emerging Microbes and Infections, Vol 9, Iss 1, Pp 2515-2525 (2020)
ABSTRACTSporotrichosis is a subcutaneous infection caused by fungi from the genus Sporothrix. It is transmitted by inoculation of infective particles found in plant-contaminated material or diseased animals, characterizing the classic sapronotic and
Externí odkaz:
https://doaj.org/article/60db119068014ab48195a7f28e81966c
Autor:
Brice Beinsteiner, Gabriel V Markov, Stéphane Erb, Yassmine Chebaro, Alastair G McEwen, Sarah Cianférani, Vincent Laudet, Dino Moras, Isabelle M L Billas
Publikováno v:
PLoS Genetics, Vol 17, Iss 4, p e1009492 (2021)
Nuclear receptors are ligand-activated transcription factors that modulate gene regulatory networks from embryonic development to adult physiology and thus represent major targets for clinical interventions in many diseases. Most nuclear receptors fu
Externí odkaz:
https://doaj.org/article/48e697a2f52f4e94a579272af3d6c135