Zobrazeno 1 - 10
of 963
pro vyhledávání: '"G. Maloney"'
Autor:
Pamela C. Köster, Ana M. Figueiredo, Jenny G. Maloney, Alejandro Dashti, Begoña Bailo, Rita T. Torres, Carlos Fonseca, Atle Mysterud, Miguel Á. Habela, Antonio Rivero-Juarez, Joaquín Vicente, Emmanuel Serrano, Maria C. Arnal, Daniel Fernández de Luco, José A. Armenteros, Ana Balseiro, Guillermo A. Cardona, João Carvalho, Dário Hipólito, Joana Fernandes, Josman D. Palmeira, Rafael Calero-Bernal, David González-Barrio, Monica Santin, David Carmena
Publikováno v:
Veterinary Research, Vol 55, Iss 1, Pp 1-12 (2024)
Abstract The ongoing increase in wild boar populations across Europe has fostered human–wildlife conflicts, including the transmission of emerging pathogens with zoonotic importance. Blastocystis is a ubiquitous, faecal-oral transmitted protist tha
Externí odkaz:
https://doaj.org/article/0b760eb0d6fe4b99a416a325f6a561ff
Autor:
S. Fiorenza, Y. Zheng, J. Purushe, T. J. Bock, J. Sarthy, D. H. Janssens, A. S. Sheih, E. L. Kimble, D. Kirchmeier, T. D. Phi, J. Gauthier, A. V. Hirayama, S. R. Riddell, Q. Wu, R. Gottardo, D. G. Maloney, J. Y. H. Yang, S. Henikoff, C. J. Turtle
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-17 (2024)
Abstract Chimeric antigen receptor-modified T cell (CAR-T) immunotherapy has revolutionised blood cancer treatment. Parsing the genetic underpinnings of T cell quality and CAR-T efficacy is challenging. Transcriptomics inform CAR-T state, but the nat
Externí odkaz:
https://doaj.org/article/99952e45b80a494cbf0a1c52b7763252
Autor:
Ariane Lozac’hmeur, Tyler Danek, Qidi Yang, Mario G. Rosasco, John S. Welch, William Y. Go, Eric W. Ng, Armen Mardiros, David G. Maloney, Edward B. Garon, Kedar Kirtane, Diane M. Simeone, Julian R. Molina, Ameen A. Salahudeen, Michelle M. Stein, J. Randolph Hecht
Publikováno v:
npj Precision Oncology, Vol 8, Iss 1, Pp 1-9 (2024)
Abstract To enable interrogation of tumor HLA LOH as a clinical diagnostic for precision oncology, we developed and validated an assay that detects HLA LOH within the context of an FDA-approved clinical diagnostic test, Tempus xT CDx. Validation was
Externí odkaz:
https://doaj.org/article/b996755a54b34fbbaaef8cbd5b2d5b9a
Publikováno v:
Journal of Food Protection, Vol 87, Iss 10, Pp 100355- (2024)
Giardia duodenalis is a globally distributed intestinal parasite that commonly infects both humans and animals. G. duodenalis is a species complex, which includes eight assemblages that vary both in genetic structure and host specificity. The prevale
Externí odkaz:
https://doaj.org/article/0df86d1393bf4386a9dab41cc881e587
Autor:
Alexandre V. Hirayama, Jocelyn H. Wright, Kimberly S. Smythe, Salvatore Fiorenza, Akira N. Shaw, Jordan Gauthier, David G. Maloney, Kikkeri N. Naresh, Cecilia C. S. Yeung, Cameron J. Turtle
Publikováno v:
HemaSphere, Vol 8, Iss 8, Pp n/a-n/a (2024)
Abstract CD19‐targeted chimeric antigen receptor T‐cell (CAR‐T) immunotherapy has transformed the management of relapsed/refractory large B‐cell lymphoma (LBCL), yet durable remissions are observed in less than half of treated patients. The t
Externí odkaz:
https://doaj.org/article/d90eb54d81b04299bea2339764f07f05
Publikováno v:
Parasites & Vectors, Vol 16, Iss 1, Pp 1-16 (2023)
Abstract Blastocystis is a common microeukaryotic intestinal parasite in humans and other animal hosts globally. However, no large-scale longitudinal study has ever been conducted for Blastocystis. To understand patterns of infection prevalence and s
Externí odkaz:
https://doaj.org/article/e63c4030edd4432dad53e328ad0dc8e2
Autor:
Guillaume Cartron, Christopher P. Fox, Fei Fei Liu, Ana Kostic, Jens Hasskarl, Daniel Li, Ashley Bonner, Yixie Zhang, David G. Maloney, John Kuruvilla
Publikováno v:
Experimental Hematology & Oncology, Vol 11, Iss 1, Pp 1-16 (2022)
Abstract Background There are no head-to-head clinical studies comparing chimeric antigen receptor (CAR) T-cell therapies for the treatment of relapsed or refractory aggressive large B-cell lymphomas. Naive, indirect comparisons may be inappropriate,
Externí odkaz:
https://doaj.org/article/698d9b2a89f14a2195e893f2e8c21cfc
Autor:
David G. Maloney, John Kuruvilla, Fei Fei Liu, Ana Kostic, Yeonhee Kim, Ashley Bonner, Yixie Zhang, Christopher P. Fox, Guillaume Cartron
Publikováno v:
Journal of Hematology & Oncology, Vol 14, Iss 1, Pp 1-17 (2021)
Abstract Background In the absence of randomized studies directly comparing chimeric antigen receptor T cell therapies, this study used matching-adjusted indirect comparisons (MAIC) to evaluate the comparative efficacy and safety of lisocabtagene mar
Externí odkaz:
https://doaj.org/article/2e2c954011864d9b8c4afd4a4a37a31f
Publikováno v:
Microorganisms, Vol 11, Iss 9, p 2171 (2023)
Cyclospora cayetanensis infections are prevalent worldwide, and the parasite has become a major public health and food safety concern. Although important efforts have been dedicated to advance toward preventing and reducing incidences of cyclosporias
Externí odkaz:
https://doaj.org/article/74b11662c7374f279e7fa9ae7916fd68
Autor:
Alyssa Sheih, Valentin Voillet, Laïla-Aïcha Hanafi, Hannah A. DeBerg, Masanao Yajima, Reed Hawkins, Vivian Gersuk, Stanley R. Riddell, David G. Maloney, Martin E. Wohlfahrt, Dnyanada Pande, Mark R. Enstrom, Hans-Peter Kiem, Jennifer E. Adair, Raphaël Gottardo, Peter S. Linsley, Cameron J. Turtle
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-13 (2020)
Understanding factors that impact CAR T cell expansion in the clinic is crucial to improving its therapeutic success. Here the authors document heterogeneity in the clonal dynamics of CAR-T cells by tracking individual clones using the endogenous TCR
Externí odkaz:
https://doaj.org/article/9a5dfb14385d4c6ba59269c0303b6190