Zobrazeno 1 - 10
of 33
pro vyhledávání: '"G. Maclaurin"'
Publikováno v:
Wind Energy Science, Vol 5, Pp 1191-1210 (2020)
We present the first synthetic aperture radar (SAR) offshore wind atlas of the US East Coast from Georgia to the Canadian border. Images from RADARSAT-1, Envisat, and Sentinel-1A/B are processed to wind maps using the geophysical model function (GMF)
Externí odkaz:
https://doaj.org/article/f94cb457fbc146eea0d2df92f43a323f
Autor:
Ruth S. Slack, Jason G. MacLaurin, Devon S. Svoboda, David S. Park, Diane C. Lagace, Mireille Khacho, Alysen Clark
Mitochondrial dysfunction is a common feature of many genetic disorders that target the brain and cognition. However, the exact role these organelles play in the etiology of such disorders is not understood. Here, we show that mitochondrial dysfuncti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4e16165878d08f189f164c8a4a451cee
https://europepmc.org/articles/PMC5886206/
https://europepmc.org/articles/PMC5886206/
Autor:
Margaret Neuspiel, Arezu Jahani-Asl, Ruth S. Slack, Eric C. Cheung, Jason G. MacLaurin, David S. Park, Andre Fortin, Heidi M. McBride
Publikováno v:
Journal of Biological Chemistry. 282:23788-23798
Of the GTPases involved in the regulation of the fusion machinery, mitofusin 2 (Mfn2) plays an important role in the nervous system as point mutations of this isoform are associated with Charcot Marie Tooth neuropathy. Here, we investigate whether Mf
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::14e71a0be3cb5ef131ceadc70af8c0a1
https://doi.org/10.1074/jbc.m703812200
https://doi.org/10.1074/jbc.m703812200
The Retinoblastoma family member p107 regulates the rate of progenitor commitment to a neuronal fate
Autor:
Kelly A. McClellan, Steve M. Callaghan, Jacqueline L. Vanderluit, Jason G. MacLaurin, Crystal A. Wylie, Andre Fortin, David S. Park, Noël Ghanem, Ruth S. Slack
Publikováno v:
The Journal of Cell Biology
The Retinoblastoma protein p107 regulates the neural precursor pool in both the developing and adult brain. As p107-deficient mice exhibit enhanced levels of Hes1, we questioned whether p107 regulates neural precursor self-renewal through the repress
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d04270dd44195758f96bf79c1eb6e4fa
https://doi.org/10.1083/jcb.200703176
https://doi.org/10.1083/jcb.200703176
Autor:
Ruth S. Slack, Devon S. Svoboda, David S. Park, Alysen Clark, Mireille Khacho, Hiromi Sesaki, Jason G. MacLaurin, Joelle Azzi, Cynthia Meghaizel, Diane C. Lagace, Mary-Ellen Harper, Marc Germain
Publikováno v:
Cell stem cell. 19(2)
Regulated mechanisms of stem cell maintenance are key to preventing stem cell depletion and aging. While mitochondrial morphology plays a fundamental role in tissue development and homeostasis, its role in stem cells remains unknown. Here, we uncover
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1e018c3b45533811f60d971c6421969d
https://pubmed.ncbi.nlm.nih.gov/27237737
https://pubmed.ncbi.nlm.nih.gov/27237737
Autor:
Karine Pilon-Larose, Laura Trinkle-Mulcahy, Heidi M. McBride, Mary-Ellen Harper, David S. Park, Ruth S. Slack, Marc Germain, Ryan J. Mailloux, David A. Patten, Jason G. MacLaurin, Mireille Khacho, Jacob Wong, Vincent Soubannier
Publikováno v:
ResearcherID
Cristae, the organized invaginations of the mitochondrial inner membrane, respond structurally to the energetic demands of the cell. The mechanism by which these dynamic changes are regulated and the consequences thereof are largely unknown. Optic at
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0f7157ed8c9f0cea67bed755f96cd9c5
https://europepmc.org/articles/PMC4282575/
https://europepmc.org/articles/PMC4282575/
Autor:
Sophie Roy, Jacqueline L. Vanderluit, Matthew T. W. Simpson, Jason G. MacLaurin, David S. Park, George S. Robertson, Donald W. Nicholson, Kerry L. Ferguson, Daigen Xu, Maria Antonietta Davoli, Ruth S. Slack
Publikováno v:
The Journal of Neuroscience. 21:7089-7098
The retinoblastoma tumor suppressor protein, pRb, is a key regulator of cell cycle and has been implicated in the terminal differentiation of neuronal cells. Mice nullizygous for pRb die by embryonic day 14.5 from hematopoietic and neurological defec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0349464747bc654f23de742300cac9cd
https://doi.org/10.1523/jneurosci.21-18-07089.2001
https://doi.org/10.1523/jneurosci.21-18-07089.2001
Autor:
T F Gendron, Robin J. Parks, Sean P. Cregan, Frank L. Graham, Paul Morley, Steven M. Callaghan, Jason G. MacLaurin, Ruth S. Slack, David S. Park
Publikováno v:
Gene Therapy. 7:1200-1209
Recombinant adenovirus vectors have provided a major advance in gene delivery systems for post-mitotic neurons. However, the use of these first generation vectors has been limited due to the onset of virally mediated effects on cellular function and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::51e9f31b3ca095a74cd29a70442beb79
https://doi.org/10.1038/sj.gt.3301208
https://doi.org/10.1038/sj.gt.3301208
Autor:
George S. Robertson, Jason G. MacLaurin, David S. Park, Sean P. Cregan, Constance Craig, Ruth S. Slack, Donald W. Nicholson
Publikováno v:
The Journal of Neuroscience. 19:7860-7869
p53 is a pivotal molecule regulating the death of neurons both after acute injury and during development. The molecular mechanisms by which p53 induces apoptosis in neuronal cells, however, are not well understood. We have shown previously that adeno
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::26f0d4579e7f76413075861c3c3998a8
https://doi.org/10.1523/jneurosci.19-18-07860.1999
https://doi.org/10.1523/jneurosci.19-18-07860.1999
Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.
K zobrazení výsledku je třeba se přihlásit.