Zobrazeno 1 - 10 of 70 pro vyhledávání: '"G. M. Segal"'
1
Constitutive and induced expression of hematopoietic growth factor genes by fibroblasts from children with Fanconi anemia
Autor: G C, Bagby, G M, Segal, A D, Auerbach, T, Onega, W, Keeble, M C, Heinrich
Publikováno v: Experimental hematology. 21(11)
The pathophysiological abnormalities leading to marrow failure and leukemogenesis in children with Fanconi anemia (FA) are not understood. We tested the hypothesis that the Fanconi anemia mutation results in insufficient production of hematopoietic g
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::dc6251feafb6ee8142b950498c0e2d76
https://pubmed.ncbi.nlm.nih.gov/7691632
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2
Specific repression of granulocyte-macrophage and granulocyte colony-stimulating factor gene expression in interleukin-1-stimulated endothelial cells with antisense oligodeoxynucleotides
Autor: G M, Segal, T D, Smith, M C, Heinrich, F S, Ey, G C, Bagby
Publikováno v: Blood. 80(3)
Antisense oligodeoxynucleotides (ODNs) have been used to effect the specific inhibition of cellular gene expression. We have evaluated the application of this approach to the inhibition of interleukin-1 (IL-1)-induced granulocyte-macrophage colony-st
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::1554282ce5d6bba14633b85e9376c58e
https://pubmed.ncbi.nlm.nih.gov/1379083
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3
Comparison of granulocyte-macrophage colony stimulating factor and interleukin-1 production from human peripheral blood mononuclear cells as measured by specific radioimmunoassays
Autor: N A, Katzen, G M, Segal, E, Vannier, J L, Nerad, M S, Klempner, C A, Dinarello
Publikováno v: European cytokine network. 3(4)
Attention has focused on cytokine networks in which gene and protein expression of some cytokines is under the influence of other cytokines. In the present studies, we addressed the relationship between the synthesis of granulocyte-macrophage colony
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::246cbc10bdacb65737ceac6c341f5b95
https://pubmed.ncbi.nlm.nih.gov/1421010
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4
Interleukin-1 stimulation stabilizes GM-CSF mRNA in human vascular endothelial cells: preliminary studies on the role of the 3' AU rich motif
Autor: G C, Bagby, G, Shaw, M C, Heinrich, S, Hefeneider, M A, Brown, T G, DeLoughery, G M, Segal, L, Band
Publikováno v: Progress in clinical and biological research. 352
To date, the notion that the AU rich motif in the 3' UT of GM-CSF mRNA can function as an IL-1 response element has not been adequately examined. We suspect that it must play some role because virtually all IL-1 inducible gene have AU rich 3' untrans
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::310aa94f1dd04b8d1e46323ca9146f1b
https://pubmed.ncbi.nlm.nih.gov/2205864
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5
Synthesis of 2-desoxy analogs of rubrosterone
Autor: K. K. Koshoev, I. V. Torgov, G. M. Segal, Zh. S. Sydykov
Publikováno v: Bulletin of the Academy of Sciences of the USSR Division of Chemical Science. 24:547-553
1. δ5,7-Androstadien-3Β,17Β-diol diacetate (VII) was synthesized from 7-ketodehydroepiandrosterone acetate (III). The oxidation of (VII) gave δ7-androsten-3Β,5α,17Βtriol-6-one 3,17-diacetate (VIII) and its 14α-hydroxy analog (XXII), which ser
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::93d98d3179f713d57d62224a9ff8b53d
https://doi.org/10.1007/bf00927475
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8
Interleukin 1 stimulates endothelial cells to release multilineage human colony-stimulating activity
Autor: G M Segal, E McCall, T Stueve, G C Bagby
Publikováno v: The Journal of Immunology. 138:1772-1778
Cultured human umbilical vein endothelial cells, when exposed to soluble products of peripheral blood monocytes, elaborate granulocyte-macrophage colony-stimulating activity (GM-CSA) and erythroid burst-promoting activity (BPA). We have performed stu
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::d60c95ce6ef62d4b1635fd856a9c5f56
https://doi.org/10.4049/jimmunol.138.6.1772
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9
Partial synthesis of 2-desoxyecdysone and 2-desoxyecdysterone, insect molting hormones
Autor: I. V. Torgov, G. M. Segal, Zh. S. Sydykov
Publikováno v: Bulletin of the Academy of Sciences of the USSR Division of Chemical Science. 31:285-292
Starting from the ketone (VIII) and specially synthesized 2-desoxypoststerone, partial syntheses of 2-desoxyecdysone and 2-desoxyecdysterone (insect molting hormones) have been carried out.
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::4da13a6f10b31799dd33908a599bd459
https://doi.org/10.1007/bf00948241
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10
Synthesis of 18-carboxy-D-homoestrone derivatives
Autor: I. V. Torgov, G. M. Segal, V. I. Maslova, K. A. Akopyan
Publikováno v: Bulletin of the Academy of Sciences of the USSR Division of Chemical Science. 23:174-178
The condensation of the thiuronium salt from 1-vinyl-6-methoxy-1-tetralol with 2-(carbethoxymethyl)-dihydroresorcinol smoothly gives the 18-carbethoxysecosteroid (III), from which, depending on the reaction conditions, the 18-carbethoxy derivatives o
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::8a3db8864b5693cb28b20e08a4f8ec5e
https://doi.org/10.1007/bf00922337
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