Zobrazeno 1 - 10 of 32 pro vyhledávání: '"G. M. Jensen"'
1
Liposomal amphotericin B-the past
Autor: R J Brüggemann, G M Jensen, C Lass-Flörl
Publikováno v: Journal of Antimicrobial Chemotherapy, 77, pp. 3-10
Journal of Antimicrobial Chemotherapy, 77, 3-10
The discovery of amphotericin B, a polyene antifungal compound, in the 1950s, and the formulation of this compound in a liposomal drug delivery system, has resulted in decades of use in systemic fungal infections. The use of liposomal amphotericin B
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::67c67b3d75680fdb317bed7c01816fad
https://pubmed.ncbi.nlm.nih.gov/36426673
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4
Impact of proximal and distal pocket site-directed mutations on the ferric/ferrous heme redox potential of yeast cytochrome c peroxidase
Autor: G. M. Jensen, D. B. Goodin
Publikováno v: Theoretical Chemistry Accounts. 130:1185-1196
Cytochrome c peroxidase (CCP) contains a five-coordinate heme active site. The reduction potential for the ferric to ferrous couple in CCP is anomalously low and pH dependent (Eo = ~−180 mV vs. S.H.E. at pH 7). The contribution of the protein envir
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::98dbb83d7c7563d230416af297a82820
https://doi.org/10.1007/s00214-011-1062-1
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5
trans-1,2-Dicyano-cyclopropane and other cyano-cyclopropane derivatives
Autor: G. M. Jensen, G. J. Jalkanen, Julian D. Gale, Karl J. Jalkanen, A. A. El-Azhary, Douglas F. McIntosh
Publikováno v: Theoretical Chemistry Accounts. 119:211-229
In this work we present the experimental vibrational absorption (VA), vibrational circular dichroism (VCD) and Raman spectra for (+)-trans-1(S),2(S)-dicyanocyclopropane and its dideuterio derivative, trans-1(S),2(S)-dicyano-1(S),2(S)-dideuteriocyclop
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::6c9b21c23eefb6d2a612ec97d3d9fcb1
https://doi.org/10.1007/s00214-007-0391-6
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6
A liposomal dispersion formulation of propofol: formulation, pharmacokinetics, stability, and identification of an oxidative degradant
Autor: G. M. Jensen, S. W. Bunte, H. Pham, C. S. Ashvar, S. Yang, N. Hu, T. H. Bunch, C. R. Skenes, J. Kennavane, C. D. Barzak, R. L. Fahrner
Publikováno v: Theoretical Chemistry Accounts. 119:291-296
Propofol is a common and highly effective anesthetic. Commercially available formulations of propofol, which is only sparingly soluble in aqueous systems, utilize emulsion technology. A liposome based dispersion formulation of propofol has been produ
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::59d37736205b0ce82a7cf27a31c9d6a6
https://doi.org/10.1007/s00214-007-0288-4
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7
Use of vibrational spectroscopy to study protein and DNA structure, hydration, and binding of biomolecules: A combined theoretical and experimental approach
Autor: Frank Herrmann, Michaela Knapp-Mohammady, V. Würtz Jürgensen, K. Frimand, Risto M. Nieminen, C. Jung, Thomas A. Niehaus, A. Rahim, Sándor Suhai, Anetta Claussen, G. M. Jensen, Frederico Nardi, Karl J. Jalkanen, Ivan Degtyarenko, Rebecca C. Wade
Publikováno v: International Journal of Quantum Chemistry. 106:1160-1198
We report on our work with vibrational absorption, vibrational circular dichroism, Raman scattering, Raman optical activity, and surface-enhanced Raman spectroscopy to study protein and DNA structure, hydration, and the binding of ligands, drugs, pes
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::6cd3fb70eada50931fe144d11850d53c
https://doi.org/10.1002/qua.20863
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8
Determination of the Relative Toxicity of Amphotericin B Formulations: A Red Blood Cell Potassium Release Assay
Autor: C. G. S. Eley, C. R. Skenes, A. Satorius, T. H. Bunch, G. M. Jensen, C. A. Weissman, N. Amirghahari, K. L. Moynihan
Publikováno v: Drug Delivery. 6:81-88
Amphotericin B remains the drug of choice for the treatment of life-threatening, systemic fungal infections. Nevertheless, the use of amphotericin B in the traditional deoxycholate formulation (d-AmB) is limited by severe toxic side effects. Several
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::408c6631c3397f4477c0ad1adcfab6e5
https://doi.org/10.1080/107175499266995
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9
Energetics of Cation Radical Formation at the Proximal Active Site Tryptophan of Cytochrome c Peroxidase and Ascorbate Peroxidase
Autor: and Arieh Warshel, D. B. Goodin, S. W. Bunte, G. M. Jensen
Publikováno v: The Journal of Physical Chemistry B. 102:8221-8228
Despite very similar protein structures, ascorbate peroxidase (APX) and yeast cytochrome c peroxidase (CCP) stabilize different radical species during enzyme turnover. Both enzymes contain similar ...
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::91a46f07bb52aa67faf10c78c386e70c
https://doi.org/10.1021/jp9811326
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10
The effect of high altitude and other risk factors on birthweight: independent or interactive effects?
Autor: G M Jensen, Lorna G. Moore
Publikováno v: American Journal of Public Health. 87:1003-1007
OBJECTIVES: This study examined whether the decline in birth-weight with increasing altitude is due to an independent effect of altitude or an exacerbation of other risk factors. METHODS: Maternal, paternal, and infant characteristics were obtained f
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9f50ed4f1d63efb6dcf7899f48f24be5
https://doi.org/10.2105/ajph.87.6.1003
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