Výsledky vyhledávání - "G. M. HOLDER"

SNOM Imaging of a Crypt-Like Feature in Adenocarcinoma Associated with Barrett's Oesophagus

Autor: Tim J. Craig, Andrzej Wolski, Peter Weightman, Andrea Varro, James Ingham, Caroline I. Smith, Andrew D. Smith, Subhasis Chattopadhyay, M. Surman, P Harrison, Michele R.F. Siggel-King, D. Mark Pritchard, Antonio Cricenti, G. M. Holder, David Martin, Steve Barrett, Marco Luce

Publikováno v: Physica status solidi. B, Basic research 255 (2018). doi:10.1002/pssb.201700518
info:cnr-pdr/source/autori:Craig, Timothy; Smith, Andrew D.; Holder, Gareth M.; Ingham, James; Smith, Caroline I.; Varro, Andrea; Pritchard, D. Mark; Barrett, Steve D.; Martin, David S.; Harrison, Paul; Wolski, Andrzej; Cricenti, Antonio; Luce, Marco; Surman, Mark; Chattopadhyay, Swapan; Weightman, Peter; Siggel-King, Michele R. F./titolo:SNOM Imaging of a Crypt-Like Feature in Adenocarcinoma Associated with Barrett's Oesophagus/doi:10.1002%2Fpssb.201700518/rivista:Physica status solidi. B, Basic research/anno:2018/pagina_da:/pagina_a:/intervallo_pagine:/volume:255
PHYSICA STATUS SOLIDI B-BASIC SOLID STATE PHYSICS

The development of more accurate and sensitive diagnostic techniques is a key factor in efforts to improve cancer survival rates. The technique of infrared aperture fibre scanning near-field optical microscopy (IR-SNOM), together with radiation from

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Near-field optical microscopy with an infra-red free electron laser applied to cancer diagnosis

Autor: P Harrison, Marco Luce, David Martin, Andrea Varro, Yuri Saveliev, Antonio Cricenti, Andy Smith, Tim J. Craig, G. M. Holder, Andrzej Wolski, Peter Weightman, M. Surman, D.J.Dunning, Michele R.F. Siggel-King, David M. Pritchard, Subhasis Chattopadhyay, Steve Barrett, Neil Thompson

Publikováno v: Applied physics letters 102 (2013): 053701. doi:10.1063/1.4790436
info:cnr-pdr/source/autori:Smith, A. D.; Siggel-King, M. R. F.; Holder, G. M.; Cricenti, A.; Luce, M.; Harrison, P.; Martin, D. S.; Surman, M.; Craig, T.; Barrett, S. D.; Wolski, A.; Dunning, D. J.; Thompson, N. R.; Saveliev, Y.; Pritchard, D. M.; Varro, A.; Chattopadhyay, S.; Weightman, P./titolo:Near-field optical microscopy with an infra-red free electron laser applied to cancer diagnosis/doi:10.1063%2F1.4790436/rivista:Applied physics letters/anno:2013/pagina_da:053701/pagina_a:/intervallo_pagine:053701/volume:102

We show that the combination of a scanning near field optical microscope and an infra-red free electron laser yields chemical images with sub-cellular spatial resolution that have the potential to provide a diagnostic for oesophageal adenocarcinoma.

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https://publications.cnr.it/doc/273713

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The influence of high intensity terahertz radiation on mammalian cell adhesion, proliferation and differentiation

Autor: D.J.Dunning, Stephen Hill, Neil Thomsen, Peter Williams, David Edgar, G. M. Holder, Julian McKenzie, Michele R.F. Siggel-King, Peter Weightman, DJ Holder, Rachel Williams, J. K. Jones, P Harrison, Frank Jackson, Yuri Saveliev, Amy Schofield, Joan E. Downes, M. Surman

Publikováno v: Physics in medicine and biology. 58(2)

Understanding the influence of exposure of biological systems to THz radiation is becoming increasingly important. There is some evidence to suggest that THz radiation can influence important activities within mammalian cells. This study evaluated th

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https://pubmed.ncbi.nlm.nih.gov/23257566

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Comparative solvolytic reactivity of bay-region diol epoxides derived from dibenz[a,j]anthracene and dibenzacridines

Autor: Subodh Kumar, Herman J. C. Yeh, Roland E. Lehr, G. M. Holder, C. Gibson, J. V. Silverton, H. Yagi, Jane M. Sayer, D M Jerina, Colin C. Duke

Publikováno v: Journal of the American Chemical Society. 112:1177-1185

On propose un mecanisme dicationique pour la solvolyse de l'epoxyde derive de la dibenzo [a,j] acridine

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https://doi.org/10.1021/ja00159a044

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Stereoselective and regioselective hydration of 7-methylbenz[c]acridine-5,6-oxide enantiomers by rodent and human microsomal epoxide hydrolases

Autor: S J, Roberts-Thomson, M E, McManus, C C, Duke, R, Agnew, G M, Holder

Publikováno v: Molecular pharmacology. 49(1)

In the present study, we studied the regioselectivity and stereoselectivity of human microsomal epoxide hydrolase-catalyzed hydration of the enantiomers of the polycyclic aza-aromatic hydrocarbon K-region oxide, 7-methylbenz[c]acridine-5,6-oxide. We

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https://pubmed.ncbi.nlm.nih.gov/8569695

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Metabolism of polycyclic aza-aromatic carcinogens catalyzed by four expressed human cytochromes P450

Autor: S J, Roberts-Thomson, M E, McManus, R H, Tukey, F J, Gonzalez, G M, Holder

Publikováno v: Cancer research. 55(5)

The role of human cytochromes P4501A1, -1A2, -3A4, and -3A5 in the metabolism of the polycyclic aza-aromatic hydrocarbons 7-methylbenz(c)acridine and dibenz(aj)acridine was investigated. The regioselectivity of the reactions was determined, as well a

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https://pubmed.ncbi.nlm.nih.gov/7866988

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ChemInform Abstract: Comparative Solvolytic Reactivity of Bay-Region Diol Epoxides Derived from Dibenz(a,j)anthracene and Dibenzacridines

Autor: Subodh Kumar, Herman J. C. Yeh, H. Yagi, J. V. Silverton, Roland E. Lehr, C. Gibson, G. M. Holder, Jane M. Sayer, D M Jerina, Colin C. Duke

Publikováno v: ChemInform. 21

On propose un mecanisme dicationique pour la solvolyse de l'epoxyde derive de la dibenzo [a,j] acridine

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::53870ec68c837c64ead29c1653875a18
https://doi.org/10.1002/chin.199019080

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Synthetic studies on potential metabolites of carcinogenic aza aromatic hydrocarbons. Part II. Non-k-region oxidised and reduced derivatives of 7-methylbenz[c]acridine

Autor: L. J. Boux, Bui Vinh Lap, G. M. Holder, H. T. A. Cheung

Publikováno v: Journal of Heterocyclic Chemistry. 20:281-284

Two phenolic derivatives of the weakly carcinogenic aza aromatic hydrocarbon 7-methylbenz[c]acridine were prepared as reference compounds for studies of the mammalian metabolism of the carcinogen. Also, 1, 2, 3, 4- and 8, 9, 10, 11-tetrahydro-7-methy

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https://doi.org/10.1002/jhet.5570200205

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Metabolism of benzo[a]pyrene

Autor: Haruhiko Yagi, Anthony Y. H. Lu, Wayne Levin, G. M. Holder, Allan H. Conney, Donald M. Jerina

Publikováno v: Archives of Biochemistry and Biophysics. 170:557-566

The metabolism of [ 14 C]benzo[a]pyrene by liver microsomes from normal and 3-methylcholanthrene-treated mice and rats was quantitatively analyzed by high pressure liquid chromatography. The ratio of dihydrodiols of benzo[a]pyrene to total metabolite

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::98559fdc4d766469d411326d96a2cc59
https://doi.org/10.1016/0003-9861(75)90151-4

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