Zobrazeno 1 - 10
of 24
pro vyhledávání: '"G. M. Fulop"'
Publikováno v:
American Journal of Reproductive Immunology. 32:15-25
PROBLEM: Immunodeficient SCID mice on the CB-17 have been used to test the role of “rejection” in a xenogeneic blastocyst transfer model of recurrent miscarriage, but interpretation of the data requires knowing syngeneic within-species matings ha
Publikováno v:
Novartis Foundation Symposia ISBN: 9780470720660
Ciba Foundation Symposium 84-Microenvironments in Haemopoietic and Lymphoid Differentiation
Ciba Foundation Symposium 84-Microenvironments in Haemopoietic and Lymphoid Differentiation
The homeostatic mechanisms which control B lymphocyte renewal in the bone marrow are unknown. Mouse bone marrow produces many small lymphocytes which develop surface IgM and other B lymphocyte properties. Putative precursors show cytoplasmic mu chain
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b723b4367461abcdc0f285e8556b45c8
https://doi.org/10.1002/9780470720660.ch5
https://doi.org/10.1002/9780470720660.ch5
Autor:
Robert A. Phillips, G. M. Fulop
Publikováno v:
Nature. 347:479-482
Mice homozygous for the scid mutation on chromosome 16 have a severe combined immune deficiency as a result of their inability to correctly rearrange their immunoglobulin and T-cell receptor genes. In scid mice, when precursors for B and T lymphocyte
Publikováno v:
The Journal of Experimental Medicine
Mice with severe combined immunodeficiency syndrome (SCID) exhibit an impairment in both T and B cell maturation, whereas myelopoiesis remains unaffected. We report here that spleens from SCID mice have undergone phenotypic expansion of cells bearing
Autor:
G M Fulop, R A Phillips
Publikováno v:
The Journal of Immunology. 136:4438-4443
Mice homozygous for an autosomal recessive mutation for the scid gene exhibit a defect that specifically impairs lymphoid differentiation but not myelopoiesis. Such mice can be cured of their lymphoid deficiency by grafts with normal bone marrow, alt
Autor:
Michelle Letarte, Christian Sirard, John E. Dick, Suzanne Kamel-Reid, Robert A. Phillips, Monica Doedens, Melvin H. Freedman, Tom Grunberger, G. M. Fulop
Publikováno v:
Scopus-Elsevier
A human acute lymphoblastic leukemia (ALL) cell line that was transplanted into immune-deficient SCID mice proliferated in the hematopoietic tissues, invaded various organs, and led to the death of the mice. The distribution of leukemic cells in SCID
Autor:
Pierre Ferrier, Lori R. Covey, George D. Yancopoulos, G. M. Fulop, Roberta R. Pollock, Frederick W. Alt, Robert A. Phillips, T K Blackwell, Barbara A. Malynn
Publikováno v:
The EMBO Journal. 8:735-742
Consistent with an ordered immunoglobulin (Ig) gene assembly process during precursor (pre-) B cell differentiation, we find that most Abelson murine leukemia virus (A-MuLV)-transformed pre-B cells derived from scid (severe combined immune deficient)
Autor:
Susan Farkas, Sandra Cockfield, P Autenried, Robert A. Phillips, Joan Urmson, G. M. Fulop, Philip F. Halloran
Publikováno v:
Transplantation. 46:68S-72S
The ability of lipopolysaccharide to induce major histocompatibility complex hyperexpressionin vivoin a variety of mouse tissues—particularly kidney—and the effect of cyclosporine on this process were studied. MHC expression was measured by a rad
Autor:
Barbara A. Malynn, L. Bruce Heinke, Andrew J.W. Furley, Frederick W. Alt, Robert A. Phillips, T. Keith Blackwell, Pierre Ferrier, George D. Yancopoulos, Gary Rathbun, G. M. Fulop
Publikováno v:
Cell. 54:453-460
Abelson murine leukemia virus-transformed precursor B lymphocytes from scid (severe combined immunodeficient) mice, like A-MuLV transformants from normal mice, actively rearrange segments of their Ig heavy chain variable region gene locus during grow
Autor:
G M, Fulop, D G, Osmond
Publikováno v:
Cellular immunology. 75(1)
To examine the influence of exogenous stimuli on the genesis of lymphocytes in mouse bone marrow, the production rate and subsets of marrow lymphocytes were examined after a systemic injection of sheep red blood cells (SRBC). Radioautographic analysi