Zobrazeno 1 - 10
of 29
pro vyhledávání: '"G. M. Drew"'
Publikováno v:
Journal of Cardiovascular Pharmacology. 33:285-291
The cardioprotective effects of the selective adenosine A1-receptor agonist, GR79236 (N-[(1S, trans)-2-hydroxycyclopentyl]adenosine), were examined in a porcine model of myocardial ischaemia-reperfusion injury. When pigs were subjected to a 50-min co
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e072595e425a19ea4a3ad5655f471156
https://doi.org/10.1097/00005344-199902000-00016
https://doi.org/10.1097/00005344-199902000-00016
Publikováno v:
British Journal of Pharmacology. 124:1467-1474
1. The potential influences of nitric oxide (NO) and prostaglandins on the renal effects of angiotensin II (Ang II) have been investigated in the captopril-treated anaesthetized rat by examining the effect of indomethacin or the NO synthase inhibitor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0a8ccd05fef521651790850e8f3ea9a2
https://doi.org/10.1038/sj.bjp.0702003
https://doi.org/10.1038/sj.bjp.0702003
Publikováno v:
British journal of pharmacology. 163(6)
While arachidonyl ethanolamine (anandamide) produces pharmacological effects mediated by cannabinoid CB1 receptors, it is also an agonist at the transient receptor potential vanilloid type 1 (TRPV1) ion channel. This study examined the cellular actio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::59175eec1d90c843c13cc480c632029f
https://pubmed.ncbi.nlm.nih.gov/21175570
https://pubmed.ncbi.nlm.nih.gov/21175570
Publikováno v:
Journal of Cardiovascular Pharmacology. 17:707-717
We compared the abilities of verapamil and nicardipine to protect the porcine myocardium from the consequences of ischaemia-reperfusion in vivo. Infusion of verapamil (50 micrograms/kg) into the left anterior descending coronary artery LAD (i.c.a.),
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::22a7926144f07276aee3c2172ed0f721
https://doi.org/10.1097/00005344-199105000-00004
https://doi.org/10.1097/00005344-199105000-00004
Publikováno v:
Journal of Cardiovascular Pharmacology. 17:267-276
The aim of this study was to investigate whether the pentobarbitone anesthetized cat is a suitable preparation in which to characterize renal tubular dopamine receptors. Intravenous infusion of dopamine (10-100 micrograms/kg/min) resulted in a dose-r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::28153d6110db9f6f323bbf8f2686f1a1
https://doi.org/10.1097/00005344-199102000-00013
https://doi.org/10.1097/00005344-199102000-00013
Autor:
I K, Anderson, G M, Drew
Publikováno v:
British journal of pharmacology. 122(7)
1. The effect of systemic administration of the nitric oxide synthase inhibitor, N(G)-nitro-L-arginine methyl ester (L-NAME) on the antihypertensive effects of the angiotensin AT1 receptor antagonist, GR138950, the angiotensin-converting enzyme (ACE)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::7d98fa21542a16b185f685cecc5c75cf
https://pubmed.ncbi.nlm.nih.gov/9421286
https://pubmed.ncbi.nlm.nih.gov/9421286
Publikováno v:
Journal of autonomic pharmacology. 17(1)
1. The antagonist activity of the angiotensin AT1 receptor antagonist, GR138950, and its haemodynamic effects have been investigated in beagle dogs. 2. In four anaesthetized dogs, GR138950 (0.1, 1 and 10 mg kg-1 i.v.), displaced dose-response curves
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::17a37f8c746e1f46f7a2aa509c6ab02f
https://pubmed.ncbi.nlm.nih.gov/9201554
https://pubmed.ncbi.nlm.nih.gov/9201554
Autor:
A, Hilditch, A A, Hunt, A, Travers, J, Polley, G M, Drew, D, Middlemiss, D B, Judd, B C, Ross, M J, Robertson
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 272(2)
The antagonist activity of GR138950 (1-[[3-bromo-2-[2-[[(trifluoromethyl)sulphonyl]amino]phenyl]-5- benzofuranyl]methyl]-4-cyclopropyl-2-ethyl-1H-imidazole-5-carboxamide) was investigated at angiotensin AT1 receptors and AT2 receptors in vitro and on
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::1cb3aebb8c206993965b7b8ee04a652d
https://pubmed.ncbi.nlm.nih.gov/7853190
https://pubmed.ncbi.nlm.nih.gov/7853190
Publikováno v:
Journal of cardiovascular pharmacology. 19(4)
Experiments were performed in anesthetized cats to compare the characteristics of angiotensin receptors in the renal and mesenteric vascular beds. Injection of either angiotensin II (Ang II; 0.3-30 ng) or angiotensin III (Ang III; 0.3-30 ng) directly
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::81eb6553a688db44d0df7d6e5a2bbbaf
https://pubmed.ncbi.nlm.nih.gov/1380593
https://pubmed.ncbi.nlm.nih.gov/1380593
Publikováno v:
Journal of hypertension. 9(12)
Experiments were performed in anaesthetized dogs to characterize the renal effects of the selective dopamine DA1-receptor agonist, fenoldopam. Intrarenal artery infusion of fenoldopam (0.01-10 micrograms/kg per min) caused dose-related renal vasodila
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::eb8bd874b71c2d8eafed111ab5040816
https://pubmed.ncbi.nlm.nih.gov/1685741
https://pubmed.ncbi.nlm.nih.gov/1685741