Zobrazeno 1 - 10
of 18
pro vyhledávání: '"G. M. Denning"'
Publikováno v:
Journal of Lipid Research, Vol 23, Iss 4, Pp 584-596 (1982)
We have investigated the extent to which modifications in the essential fatty acid content of mammalian cells can affect prostaglandin production. Swiss mouse 3T3 cells stimulated with the calcium ionophore A23187 produced 1.7 to 7 times more prostag
Externí odkaz:
https://doaj.org/article/68da1b97dd3542ed8b49e85e623d7056
Publikováno v:
Journal of Lipid Research, Vol 20, Iss 4, Pp 536-547 (1979)
The fatty acid composition of human skin fibroblasts grown in 10% dialyzed fetal calf serum can be modified considerably by adding supplemental fatty acids to the culture medium. The degree of modification was dependent on the concentration of added
Externí odkaz:
https://doaj.org/article/22d5cb6a8b3d46769b004303dc7da469
Publikováno v:
Journal of Lipid Research, Vol 24, Iss 8, Pp 993-1001 (1983)
Arachidonic acid was incorporated into triglycerides by cultured bovine endothelial cells in a time- and concentration-dependent manner. At 75 microM or higher, more arachidonic acid was incorporated into triglycerides than into phospholipids. The tr
Externí odkaz:
https://doaj.org/article/8cf9e699bd6e49c0b242b2279f882677
Autor:
G M Denning
Publikováno v:
The Journal of Immunology. 156:4807-4814
IL-4 and IFN-gamma increase release of secretory component (SC), the polymeric IgA (plgA)-binding segment of the plgA receptor (plgAR), by the human intestinal epithelial cell line HT29. Moreover, these two cytokines synergistically increase plgA bin
Autor:
M L, McCormick, G M, Denning, K J, Reszka, P, Bilski, G R, Buettner, G T, Rasmussen, M A, Railsback, B E, Britigan
Publikováno v:
The Biochemical journal.
Because cell-mediated reduction of menadione leads to the generation of reactive oxygen species (ROS), this quinone is widely used to investigate the effects of ROS on cellular functions. We report that A549 human lung epithelial cells exposed to men
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 162(9)
Delivery of IgA to the mucosal surface occurs via transcytosis of polymeric IgA (pIgA) across the epithelium, a process mediated by the pIgR. Several factors increase pIgR expression in human epithelial cells, including IL-4 and IFN-gamma. Using an R
Autor:
G M, Denning, K G, Leidal, V A, Holst, S S, Iyer, D W, Pearson, J R, Clark, W M, Nauseef, R A, Clark
Publikováno v:
Blood. 90(1)
Calreticulin is a soluble endoplasmic reticulum protein comprising the major storage reservoir for inositol trisphosphate-releasable calcium. Although its highly conserved primary structure and a wide range of functions have been well described, less
Publikováno v:
The Journal of biological chemistry. 269(6)
Platelet-activating factor (PAF) is a potent mediator which produces a wide range of biological responses by binding to specific, high affinity receptors on the target cell surface. In addition, we and others have observed cellular responses to PAF w
Publikováno v:
Journal of cell science. Supplement. 17
The cystic fibrosis transmembrane conductance regulator (CFTR) is mutated in patients with cystic fibrosis (CF). The most common CF-associated mutation is deletion of phenylalanine at residue 508, CFTR delta F508. When expressed in heterologous cells
Autor:
G M, Denning, M J, Welsh
Publikováno v:
The Journal of biological chemistry. 266(20)
Bradykinin stimulates Cl- secretion by airway epithelia, but different patterns of secretion result from addition to the mucosal and submucosal surfaces. Earlier work suggested that bradykinin activates two second messenger pathways: increasing inosi