Výsledky vyhledávání - "G. M. Alekseeva"

Akademický článek

Composition and Technology Development for Obtaining Amorphous Solid Dispersion of Ebastine by Hot Melt Extrusion to Increase Dissolution Rate

Autor: K. A. Gusev, A. R. Aliev, Yu. E. Generalova, N. A. Aksenova, G. V. Rechkalov, D. N. Maimistov, G. M. Alekseeva, E. V. Flisyuk

Publikováno v: Разработка и регистрация лекарственных средств, Vol 12, Iss 4, Pp 126-135 (2023)

Introduction. Ebastine is a second-generation antihistamine drug available in the form of orally disintegrating tablets and film-coated tablets. Ebastine substance exhibits high bioavailability, but low solubility in water and gastrointestinal tract

Externí odkaz: https://doaj.org/article/d33d26183258451a85d80f5ef230f390

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Akademický článek

EXPLORING OF ACID-BASIC PROPERTIES, DEVELOPMENT AND VALIDATION OF THE METHOD OF QUANTITATIVE DETERMINATION OF ORIGINAL PHARMACEUTICAL SUBSTANCE

Autor: G. M. Alekseeva, V. F. Apraksin, Yu. E. Generalova

Publikováno v: Разработка и регистрация лекарственных средств, Vol 8, Iss 1, Pp 66-71 (2019)

Introduction. The object of analysis was a newly synthesized organic substance, a derivative of 4-aminobenzoic acid and malonic ester – 4,4’-(propandiamido) sodium dibenzoate, which has an antisteatotic effect. For the quantitative determination

Externí odkaz: https://doaj.org/article/8c7e4c5cc67f46c2b9496f8f822672c8

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Akademický článek

A COMPARATIVE STUDY OF METHODS OF THE SALICYLIC ACID CHLORINATION FOR FURTHER PRODUCTION OF ANTIHELMINTHIC DRUGS

Autor: V. G. Dudarev, M. R. Kuzminykh, G. M. Alekseeva

Publikováno v: Разработка и регистрация лекарственных средств, Vol 0, Iss 3, Pp 82-87 (2019)

With the help of thin-layer and high-performance liquid chromatography, the change in the composition of the reaction mass during the chlorination of salicylic acid was studied by three methods: molecular chlorine in acetic acid, sodium hypochlorite

Externí odkaz: https://doaj.org/article/2538840126084a9e9c120e8b28476386

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EXPERIENCE IN USING DISTANCE LEARNING SYSTEMS AT UNIVERSITIES OF UKRAINE AND MEXICO

Autor: G. M. Alekseeva, O. G. Kuzminska, L. V. Horbatiuk, N. V. Kravchenko

Publikováno v: Scientific papers of Berdiansk State Pedagogical University Series Pedagogical sciences. 1:11-27

The basic didactic principles of distance and traditional forms of education are considered. The use of learning management systems (Learning Management System) is relevant in the context of the COVID-19 pandemic. In the process of transition of educ

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::53710b5e8463fe60a2ca16d2e21a9d98
https://doi.org/10.31494/2412-9208-2021-1-2-11-27

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Stepwise injection photometric determination of ascorbic acid in drugs

Autor: G. M. Alekseeva, Leonid Moskvin, Andrey Bulatov, T. D. Sineva, U. M. Strashnova, A. L. Moskvin, A. B. Vishnikin

Publikováno v: Journal of Analytical Chemistry. 66:275-279

A procedure is developed for the photometric determination of ascorbic acid in drug preparations. It is based on the rapid and highly selective reaction of ascorbic acid with a novel reagent, the guanidinium salt of 1-bismuto-11-molybdophosphoric het

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::dac3c982d7e40a94a8c66417e177b652
https://doi.org/10.1134/s106193481103004x

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Potentiometric study on acid properties of some 4-hydroxy-6H-1,3-oxazin-6-ones. Structure-biological activity relationship

Autor: O. A. Petina, G. M. Alekseeva, N. N. Kuz’mich, I. P. Yakovlev, V. E. Zakhs, B. Yu. Lalaev

Publikováno v: Russian Journal of General Chemistry. 76:645-648

4-Hydroxy-6H-1,3oxazin-6-ones exhibit properties of weak OH acids. These compounds are readily methylated with diazomethane to give the corresponding 4-methoxy derivatives. According to the potentiometric titration data, the pKa values of 2-methoxy-a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::466bb4e8fc728f71f7c0d4dda5ceafd7
https://doi.org/10.1134/s1070363206040256

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Triamine-type complexes of platinum(II) and their antitumor properties

Autor: G. M. Alekseeva, A. I. Stetsenko, A. L. Konovalova, K. I. Yakovlev

Publikováno v: Theoretical and Experimental Chemistry. 27:308-314

Triamines of platinum(II) (Pt(NH3)2LCl]Cl with a cis-structure (L represents cytosine, cytidine, isocytosine, theobromine, theophylline) and cis- and trans-isomers with theophylline and inosine were synthesized. The coordination formulas were demonst

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::ae9cf3c2b4af2b106e83cfd192a8e5b7
https://doi.org/10.1007/bf01372500

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