Zobrazeno 1 - 10
of 72
pro vyhledávání: '"G. M. Aber"'
Publikováno v:
Clinica Chimica Acta. 259:137-146
This study examined the effect of the angiotensin converting enzyme (ACE) inhibitor, enalaprilat, on mesangial cell (MC) DNA synthesis induced by H2O2, IL-6 and PDGF. MC were incubated with enalaprilat (2.5-100 mumol/l) alone and together with combin
Publikováno v:
Clinical Science. 85:747-751
1. This study examined the influence of H2O2, interleukin-6 and platelet-derived growth factor on the proliferation of rat mesangial cells. Mesangial cells were exposed to either a single pulse or three daily pulses of H2O2 (10−8-10−4 mol/l), alo
Publikováno v:
British Journal of Pharmacology. 108:327-330
1. This study was designed to investigate whether the angiotensin converting enzyme (ACE) inhibitors, captopril, enalapril and fosinopril have a dose-dependent effect on the production of prostaglandin E2 (PGE2), prostaglandin I2 (prostacyclin, PGI2)
Autor:
Richard C. Strange, R. J. D'souza, L. Clayton, Christopher Hiley, Simon J. Davies, G. M. Aber, Peter W. Jones
Publikováno v:
Free Radical Research Communications. 18:107-113
1. The effect of H2O2 (4.7 x 10(-9) -4.7 x 10(-3) M) on prostanoid production by isolated glomeruli from normotensive (WKY) and, spontaneously hypertensive rats (SHR) has been studied. 2. Oxidant stress significantly increased synthesis of prostaglan
Publikováno v:
Hypertension in Pregnancy. 12:103-111
The effect of varying dietary protein intake from 16% to 35% (w/w) on glomerular binding of angiotensin II (AngII) has been studied in virgin and pregnant normotensive and spontaneously hypertensive rats. Although the higher protein diet caused an in
Publikováno v:
Clinical Science. 82:389-395
1. The effect of oestradiol alone and in combination with indomethacin on blood pressure, erythrocyte cation concentration and Na+−K+ flux has been studied in adult female normotensive and spontaneously hypertensive rats. 2. Oestradiol alone result
Autor:
Simon J. Davies, Peter W. Jones, Christopher Hiley, Richard C. Strange, Lisa Clayton, R. J. D'souza, G. M. Aber
Publikováno v:
Free Radical Research Communications. 17:271-278
The sensitivity of isolated glomeruli from normotensive (Wistar-Kyoto, WKY) and spontaneously hypertensive (SHR) strains to oxidant stress was studied by determining the incidence of pyknosis, karyohexis and karyolysis after incubation with different
Publikováno v:
Hypertension in Pregnancy. 9:43-56
The binding characteristics of 125I Angiotensin II (Ang II) by glomeruli has been studied in virgin and pregnant normotensive (NTR) and spontaneously hypertensive rats (SHR).Although pregnancy induced a fall in ANG II binding by glomeruli from both s
Autor:
G. M. Aber, Helen Philips, Simon J. Davies, Richard D'Sousa, Richard C. Strange, Christopher Hiley, John D. Hayes, Derek L. Mattey
Publikováno v:
Biochimica et biophysica acta. 1157(2)
We describe studies in whole kidney, cortical and medullary homogenates and, glomerular cells in culture to determine the relative levels of expression of α (Ya, Yc, Yk), μ (Yb1/Yb2), π (Yf) glutathione S -transferases (GST) and CuZn superoxide di
Publikováno v:
Clinical science (London, England : 1979). 81(4)
1. This study was designed to examine the production of certain eicosanoids (prostaglandin E2), prostacyclin (as 6-keto-prostaglandin F1α) and thromboxane A2 (as thromboxane B2) by glomeruli isolated from normotensive Wistar-Kyoto and spontaneously