Zobrazeno 1 - 10
of 282
pro vyhledávání: '"G. Lavery"'
Autor:
S. P. Mollan, B. R. Wakerley, Z. Alimajstorovic, J. Mitchell, R. Ottridge, A. Yiangou, M. Thaller, A. Gupta, O. Grech, G. Lavery, K. Brock, A. J. Sinclair
Publikováno v:
The Journal of Headache and Pain, Vol 22, Iss 1, Pp 1-9 (2021)
Abstract Objective Headache is the predominant disabler in idiopathic intracranial hypertension (IIH). The aim was to characterise headache and investigate the association with intracranial pressure. Methods IIH:WT was a randomised controlled paralle
Externí odkaz:
https://doaj.org/article/e861e1d6ffc1479e99c4217ac81bc889
Autor:
S. Mollan, B. Wakerley, Z. Alimajstorovic, J.L. Mitchell, R. Ottridge, A. Yiagnou, M. Thaller, O. Grech, G. Lavery, K. Brock, A. Sinclair
Publikováno v:
Brain and Spine, Vol 1, Iss , Pp 100753- (2021)
Externí odkaz:
https://doaj.org/article/b45ff69886a54fadb38e62b44b4889a5
Autor:
S. Mollan, J.L. Mitchell, R. Ottridge, M. Aguiar, A. Yiangou, Z. Alimajstorovic, D. Cartwright, O. Grech, G. Lavery, C. Westgate, V. Vijay, W. Scotton, B. Wakerley, T. Matthews, A. Ansons, S. Hickman, J. Benzimra, C. Rick, R. Singhal, A. Tahrani, K. Brock, E. Frew, A. Sinclair
Publikováno v:
Brain and Spine, Vol 1, Iss , Pp 100755- (2021)
Externí odkaz:
https://doaj.org/article/39877ecd30e54559b8e614df97d55742
Autor:
Federica Cuozzo, Katrina Viloria, Ali H. Shilleh, Daniela Nasteska, Charlotte Frazer-Morris, Jason Tong, Zicong Jiao, Adam Boufersaoui, Bryan Marzullo, Daniel B. Rosoff, Hannah R. Smith, Caroline Bonner, Julie Kerr-Conte, Francois Pattou, Rita Nano, Lorenzo Piemonti, Paul R.V. Johnson, Rebecca Spiers, Jennie Roberts, Gareth G. Lavery, Anne Clark, Carlo D.L. Ceresa, David W. Ray, Leanne Hodson, Amy P. Davies, Guy A. Rutter, Masaya Oshima, Raphaël Scharfmann, Matthew J. Merrins, Ildem Akerman, Daniel A. Tennant, Christian Ludwig, David J. Hodson
Publikováno v:
Cell Reports, Vol 43, Iss 4, Pp 114047- (2024)
Summary: Using 13C6 glucose labeling coupled to gas chromatography-mass spectrometry and 2D 1H-13C heteronuclear single quantum coherence NMR spectroscopy, we have obtained a comparative high-resolution map of glucose fate underpinning β cell functi
Externí odkaz:
https://doaj.org/article/2e924f2360b54e9dbc6f6da13e566a04
Autor:
Jonathan I. Quinlan, Amritpal Dhaliwal, Felicity R. Williams, Sophie L. Allen, Surabhi Choudhary, Alex Rowlands, Leigh Breen, Gareth G. Lavery, Janet M. Lord, Ahmed M. Elsharkawy, Matthew J. Armstrong, Carolyn A. Greig
Publikováno v:
Experimental Physiology, Vol 108, Iss 8, Pp 1066-1079 (2023)
Abstract Sarcopenia is associated with reduced quality of life and increased mortality in patients with end stage liver disease (ESLD). Historically, sarcopenia identification in ESLD utilised L3 skeletal muscle index (SMI). There are few data on mus
Externí odkaz:
https://doaj.org/article/4246730362f141029109dfd801eee9a9
Autor:
Arnold Tan, Awais Z. Younis, Alexander Evans, Jade V. Creighton, Clare Coveny, David J. Boocock, Craig Sale, Gareth G. Lavery, Amanda S. Coutts, Craig L. Doig
Publikováno v:
Cell Death Discovery, Vol 9, Iss 1, Pp 1-13 (2023)
Abstract The ADP-ribosyltransferase, PARP1 enzymatically generates and applies the post-translational modification, ADP-Ribose (ADPR). PARP1 roles in genome maintenance are well described, but recent work highlights roles in many fundamental processe
Externí odkaz:
https://doaj.org/article/53b6b599c8154c79ab5165547b13a0c9
Autor:
Verena M. Merk, Truong San Phan, Alice Wiedmann, Rowan S. Hardy, Gareth G. Lavery, Thomas Brunner
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
BackgroundExtra-adrenal glucocorticoid (GC) synthesis at epithelial barriers, such as skin and intestine, has been shown to be important in the local regulation of inflammation. However, the role of local GC synthesis in the lung is less well studied
Externí odkaz:
https://doaj.org/article/f2db5356f93f4035922c09efc1c98a24
Autor:
Olivia Grech, Matilde Sassani, Gisela Terwindt, Gareth G. Lavery, Susan P. Mollan, Alexandra J. Sinclair
Publikováno v:
The Journal of Headache and Pain, Vol 23, Iss 1, Pp 1-12 (2022)
Abstract Background Migraine is a highly prevalent disorder with significant economical and personal burden. Despite the development of effective therapeutics, the causes which precipitate migraine attacks remain elusive. Clinical studies have highli
Externí odkaz:
https://doaj.org/article/1250d6f1d88b404195af0c35d2b334d4
Autor:
Congxin Sun, Elena Seranova, Malkiel A. Cohen, Miruna Chipara, Jennie Roberts, Dewi Astuti, Adina M. Palhegyi, Animesh Acharjee, Lucia Sedlackova, Tetsushi Kataura, Elsje G. Otten, Prashanta K. Panda, Samuel Lara-Reyna, Miriam E. Korsgen, Kevin J. Kauffman, Alejandro Huerta-Uribe, Malgorzata Zatyka, Luiz F.S.E. Silva, Jorge Torresi, Shupei Zhang, Georgina W. Hughes, Carl Ward, Erich R. Kuechler, David Cartwright, Sergey Trushin, Eugenia Trushina, Gaurav Sahay, Yosef Buganim, Gareth G. Lavery, Joerg Gsponer, Daniel G. Anderson, Eva-Maria Frickel, Tatiana R. Rosenstock, Timothy Barrett, Oliver D.K. Maddocks, Daniel A. Tennant, Haoyi Wang, Rudolf Jaenisch, Viktor I. Korolchuk, Sovan Sarkar
Publikováno v:
Cell Reports, Vol 42, Iss 5, Pp 112372- (2023)
Summary: Autophagy is a homeostatic process critical for cellular survival, and its malfunction is implicated in human diseases including neurodegeneration. Loss of autophagy contributes to cytotoxicity and tissue degeneration, but the mechanistic un
Externí odkaz:
https://doaj.org/article/b83b8c0b9a4f4ed78cbd46982db1f23d
Publikováno v:
Frontiers in Physiology, Vol 14 (2023)
Methods of isolating mitochondria commonly utilise mechanical force and shear stress to homogenize tissue followed by purification by multiple rounds of ultracentrifugation. Existing protocols can be time-consuming with some physically impairing inte
Externí odkaz:
https://doaj.org/article/191f5d69f4004e6c8b17d6a0a961b7c9