Thromboxane Biosynthesis in Cancer Patients and its Inhibition by Aspirin: A Sub-Study of the Add-Aspirin Trial

Autor: Joharatnam-Hogan, Nalinie, H. Cafferty, Fay, Petrucci, Giovanna, Cameron, David A, Ring, Alistair, G. Kynaston, Howard, C. Gilbert, Duncan, H. Wilson, Richard, A. Hubner, Richard, E. B Swinson, Daniel, Cleary, Siobhan, Robbins, Alex, MacKenzie, Mairead, W.G. Scott-Brown, Martin, Sothi, Sharmila, Dawson, Lesley, M. Capaldi, Lisa, Churn, Mark, Cunningham, David, Khoo, Vincent, C. Armstrong, Anne, L. Ainsworth, Nicola, Horan, Gail, A. Wheatley, Duncan, Mullen, Russell, J. Loftus, Fiona, Walther, Axel, A. Herbertson, Rebecca, D. Eaton, John, O'Callaghan, Ann, Eichholz, Andrew, Mubashir Kagzi, Mohammed, M. Patterson, Daniel, Narahari, Krishna, Bradbury, Jennifer, Stokes, Zuzana, J. Rizvi, Azhar, A. Walker, Georgina, L. Kunene, Victoria, Srihari, Narayanan, Gentry-Maharaj, Aleksandra, Meade, Angela, Patrono, Carlo, Rocca, Bianca, E. Langley, Ruth

Publikováno v: Joharatnam-Hogan, N, H. Cafferty, F, Petrucci, G, Cameron, D A, Ring, A, G. Kynaston, H, C. Gilbert, D, H. Wilson, R, A. Hubner, R, E. B Swinson, D, Cleary, S, Robbins, A, MacKenzie, M, W.G. Scott-Brown, M, Sothi, S, Dawson, L, M. Capaldi, L, Churn, M, Cunningham, D, Khoo, V, C. Armstrong, A, L. Ainsworth, N, Horan, G, A. Wheatley, D, Mullen, R, J. Loftus, F, Walther, A, A. Herbertson, R, D. Eaton, J, O'Callaghan, A, Eichholz, A, Mubashir Kagzi, M, M. Patterson, D, Narahari, K, Bradbury, J, Stokes, Z, J. Rizvi, A, A. Walker, G, L. Kunene, V, Srihari, N, Gentry-Maharaj, A, Meade, A, Patrono, C, Rocca, B & E. Langley, R 2023, ' Thromboxane Biosynthesis in Cancer Patients and its Inhibition by Aspirin: A Sub-Study of the Add-Aspirin Trial ', British Journal of Cancer .

BackgroundPre-clinical models demonstrate that platelet activation is involved in the spread of malignancy. Ongoing clinical trials are assessing whether aspirin, which inhibits platelet activation, can prevent or delay metastases.MethodsUrinary 11-d

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______3094::6af9ec32a7515375649e083ab18e2bfe
https://www.pure.ed.ac.uk/ws/files/364289576/s41416_023_02310_1.pdf