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pro vyhledávání: '"G. Joe Stephenson"'
Autor:
Gregory W. Gladish, Mandy Parson, Yining Ye, George R. Blumenschein, Karen L. Reckamp, G. Joe Stephenson, Jesse McGreivy, Timothy J. O'Rourke, Yu Nien Sun, Alan Sandler
Publikováno v:
Clinical Cancer Research. 16:279-290
Purpose: Motesanib is a small-molecule antagonist of vascular endothelial growth factor receptor 1, 2, and 3, platelet-derived growth factor receptor, and Kit. This phase 1b study assessed the safety, maximum tolerated dose (MTD), and pharmacokinetic